In-vitro and in-vivo efficacy of zinc acetate against Propionibacteria alone and in combination with erythromycin

Zentralblatt fur Bakteriologie

Volumn 289, Issue 4, 1999, Pages 445-456

  Fluhr, Joachim W ^a   Bösch, Bettina ^a   Gloor, Max ^a   Höffler, Ulrich ^b  

^a Klinikum Karlsruhe   (Germany)

^b KLINIKUM LUDWIGSHAFEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 2442761725     PISSN: 09348840     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0934-8840(99)80084-X     Document Type: Article

References (28)

1. Bojar, R. A., E. A. Eady, C. E. Jones, W. J. Cunliffe, and K. T. Holland: Inhibition of erythromycin-resistant propionibacteria on the skin of acne patients by topical erythromycin with and without zinc. Br. J. Dermatol. 130 (1994) 329-336
2. Chvapil, M.: Effect of zinc on cells and biomembranes. Med. Clin. North Am. 60 (1976) 799-812
3. DIN 58940/DIN 58944. In: DIN-Taschenbuch Medizinische Mikrobiologie und Immunologie. Beuth Verlag, Berlin (1992)
4. Eady, E. A., J. H. Cove, J. Blake, K. T. Holland, and W. J. Cunliffe: Recalcitrant acne vulgaris. Clinical, biochemical and microbiological investigation of patients not responding to antibiotic treatment. Br. J. Dermatol. 118 (1988) 415-423
5. Eady, E. A., J. H. Cove, K. T. Holland, and W. J. Cunliffe: Erythromycin resistant propionibacteria in antibiotic treated acne patients: association with therapeutic failure. Br. J. Dermatol. 121 (1989) 51-57
6. Eady, E. A., C. E. Jones, K. J. Gardner, J. P. Taylor, J. H. Cove, and W. J. Cunliffe: Tetracycline-resistant propionibacteria from acne patients are cross-resistant to doxycycline, but sensitive to minocycline. Br. J. Dermatol. 128 (1993) 556-560
7. Eady, E. A., C. E. Jones, S. Vyarkman, J. F. Cove, and W. J. Cunliffe: Increasing prevalence of antibiotic resistant propionibacteria on the skin of acne patients: Results of a five year study. Br. J. Dermatol. 137 (1997) Suppl. 50, 27-28
8. Farmery, M. R., C. E. Jones, E. A. Eady, and W. J. Cunliffe: In vitro activity of azelaic acid, benzoyl peroxide and zinc acetate against antibiotic-resistant propionibacteria from acne patients. J. Dermatol. Treat. 5 (1994) 63-65
9. Fluhr, J. W., M. Gloor, P. Dietz, and U. Höffler: In vitro activity of 6 antimicrobials against propionibacteria isolates from untreated acne papulopustulosa. Zent. bl. Bakteriol. - Int. J. Med. Microbiol. 289 (1999) 53-61
10. Forssman, Th., M. Gloor und W. Gehring: Antibiotikaresistenzen bei Acne vulgaris - Eine retrospektive Untersuchung an einem antibiotisch vorbehandelten und einem unbehandelten Kollektiv. Z. Hautkr. 69 (1994) 828-832
11. Gollnick, H. und A. Melzer: Erythromycin und eine Erythromycin-Zink-Kombination in der topischen Aknetherapie. Z. f. Dermatologie 183 (1997) 8-18
12. ®) in acne vulgaris: a randomized, double-blind comparative study. Br. J. Dermatol. 121 (1989) 497-502
13. Höffler, U., H. L. Ko, and G. Pulverer: Antimicrobial susceptibility of Propionibacterium acnes and related microbial species. Antimicrob. Agents Chemother. 10 (1976) 387-394
14. Höffler, U., W. Niederau, and G. Pulverer: Susceptibility of cutaneous propionibacteria to newer antiobiotics. Chemother. 26 (1980) 7-11
15. Höffler, U.: Resistenzinduktion nach topischer antimikrobieller Akne-Therapie? Hautarzt 36 (1985) Suppl. VIII, 175-177
16. Holland, K. T., C. D. Roberts, W. J. Cunliffe, and M. Williams: A technique for sampling micro-organisms from the pilo-sebaceous ducts. J. appl. Bact. 37 (1974) 289-308
17. Holland, K. T., R. A. Bojar, W. J. Cunliffe, A. G. Cucliffe, E. A. Eady, L. Farooq, A. M. Farrell, E. M. Gribbon, and D. Taylor: The effect of zinc and erythromycin on the growth of erythromycin-resistant and erythromycin-sensitive isolates of Propionibacterium acnes: an in-vitro study. Br. J. Dermatol. 126 (1992) 505-509
18. Krogstadt, D. J. and R. C. Moellering: Combination of antibiotics, mechanisms of interaction against bacteria. In: Antibiotics in laboratory medicine. Ed.: Lorian V., Williams & Wilkins, Baltimore, London (1986) pp. 537-594
19. Kurokawa, I., S. Nishijima, and Y. Asada: The antibiotic susceptibility of Propionibacterium acnes: a 15 year bacteriological study and retrospective evaluation: J. Dermatol. 15 (1988) 149-154
20. Leyden, J. J., K. J. Mc Ginley, S. Cavalieri, G. F. Webster, O. H. Mills, and A. M. Kligman: Propionibacterium acnes resistance to antibiotics in acne patients. J. Am. Acad. Dermatol. 8 (1983) 41-45
21. Maurer, W., L. Hothorn, and W. Lehmacher: Multiple comparison in drug clinical trials and preclinical assays. In: Vollmar, J.: Biometrie in der chemisch-pharmazeutischen Industrie. Vol. 6, p. 3-21, Fischer, Stuttgart 1995
22. ®. Clin. Exp. Dermatol. 18 (1993) 410-413
23. Plewig, G. und M. Kligman: Akne und Rosazea. Springer-Verlag, Berlin, Heidelberg, (1994) p. 36
24. Schachner, L., W. Eaglstein, C. Kittles, and P. Mertz: Topical erythromycin and zinc therapy for acne. J. Am. Acad. Dermatol. 22 (1990) 253-260
25. Schachner, L., A. Pestana, and C. Kittles: A clinical trial comparing the savety and efficacy of a topical erythromycin-zinc formulation with a topical clindamycin formulation. J. Am. Acad. Dermatol. 22 (1990) 489-495
26. Stamatiadis, D., M. C. Bulteau-Portois, and I. Mowszowics: Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid. Br. J. Dermatol 119 (1988) 627-632
27. Strauss, J. S. and A. M. Stranieri: Acne treatment with topical erythromycin and zinc: Effect on propionibacterium acnes and free fatty acid composition. J. Am. Acad. Dermatol. 11 (1984) 86-89
28. Sugimoto, Y., I. López-Solache, and F. Labrie: Cations inhibit specifically type I 5α-reductase found in human skin. J. Invest. Derm. 104 (1995) 775-778