Novel series of [ddN]-[TSAO-T] heterodimers as potential bi-functional inhibitors of HIV-1 RT. Studies in the linker and ddN region

Nucleosides and Nucleotides

Volumn 18, Issue 4-5, 1999, Pages 1029-1030

  Velazquez S ^a   Tunon V ^a   Jimeno, M L ^a   Perez Perez M J ^a   San Felix A ^a   Chamorro, C ^a   Lobaton E ^a   Esteban Gamboa, A ^a   De Clercq, E ^b   Balzarini, J ^b   Camarasa, M J ^a  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; CONFERENCE PAPER; DRUG RESEARCH; DRUG STRUCTURE; STRUCTURE ACTIVITY RELATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 2442728889     PISSN: 07328311     EISSN: None     Source Type: Journal    
DOI: 10.1080/15257779908041640     Document Type: Conference Paper

References (4)

1. Richman, D.; Rosenthal, A.S.; Skoog, M.; Eckner, R.I.; Chou, T.-C.; Sabo, J.P.; Merluzzi, V.J. Antimicrob. Agents. Chemother. 1991, 35, 305-308.
2. Balzarini, J.; Karlsson, A.; Pérez-Pérez, M.J.; Camarasa, M.J.; Tarpley, W.G.; De Clercq E. J. Virol. 1993, 67, 5353-5359.
3. Velázquez, S.; Alvarez, R.; San-Félix, A.; Jimeno, M.L.; De Clercq, E.; Balzarini, J.; Camarasa, M.J. J. Med. Chem. 1995, 38, 1641-1649.
4. McGuigan, C.; Cahard, D.; Sheeka, H.M.; De Clercq, E.; Balzarini, J. J. Med. Chem. 1996, 39, 1748-1753.