Application of DNA chip techniques for Yq microdeletion analysis in infertile males

Experimental and Molecular Medicine

Volumn 36, Issue 2, 2004, Pages 179-184

  Lee, Suman ^a   Joo, Hyun Suk ^b   Lee, Sook Hwan ^a   Park, Jung Eun ^b   Kim, Jong Man ^b   Hwang, Jae Hoon ^b   Cho, Key Seung ^b   Hwang, Seung Yong ^b  

^a CHA University   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

DNA chip; Male infertility; Microdeletion; Molecular diagnosis; STS

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; CHROMOSOME DELETION; CHROMOSOME MICRODELETION; CHROMOSOME YQ; CONTROLLED STUDY; DNA MICROARRAY; DNA SEQUENCE; GEL ELECTROPHORESIS; HUMAN; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; MARKER GENE; OLIGOATHENOTERATOZOOSPERMIA; OLIGOSPERMIA; POLYMERASE CHAIN REACTION; SEQUENCE TAGGED SITE;

EID: 2442719189     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2004.25     Document Type: Article

References (14)

1. Bor P, Hindkjaer J, Ingerslev HJ, Kolvraa S. Multiplex PCR for screening of microdeletions on the Y chromosome. J Assist Reprod Genet 2001;18:291-8
2. Chandley AC, Cooke HJ. Human male fertility-Y-linked genes and spermatogenesis. Hum Mol Genet 1994;3:1449-52
3. Dohle GR, Halley DJ, Van Hemel JO, van den Ouwel AM, Pieters MH, Weber RF, Govaerts LC. Genetic risk factors in infertile men with severe oligozoospermia and azoo spermia. Hum Reprod 2002;17:13-6
4. Foresta C, Ferlin A, Garolla A, Moro E, Pistorello M, Barbaux S, Rossato M. High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome. Hum Reprod 1998;13:302-7
5. Foresta C, Moro E, Ferlin A. Y chromosome microdeletions and alterations of spermatogenesis. Endocr Rev 2001;22:226-39
6. Fortina P, Surrey S, Kricka LJ. Molecular diagnostics: hurdles for clinical implementation. Trends Mol Med 2002;8:264-6
7. Hwang SY, Lim GB. DNA chip technologies. Biotech Biopro Eng 2000;5:159-63
8. Kamp C, Huellen K, Fernandes S, Sousa M, Schlegel PN, Mielnik A, Kleiman S, Yavetz H, Krause W, Kupker W. High deletion frequency of the complete AZFa sequence in men with Sertoli-cell-only syndrome. Mol Hum Reprod 2001;7:987-94
9. Kim JR, Lee SR, Chung HJ, Kim SY, Baek SW, Kim JH, Kim YS. Identification of amyloid β-peptide responsive genes by cDNA chip technology: Involvement of RTP801 in amyloid β-peptide toxicity. Exp Mol Med 2003;35:403-11
10. Lee S, Kim NK, Kim HJ, Lee SH, Jeong HJ, Cha KY. Genetic analysis of three polymorphic sites of LH β-subunit gene in infertile Korean men with nonobstructive azoospermia. Fertil Steril 2003;79:517-21
11. Maurer B, Simoni M. Y chromosome microdeletion screening in infertile men. J Endocrinol Invest 2000;23:664-70
12. Sawai H, Komori S, Koyama K. Molecular analysis of the Y chromosome AZFc region in Japanese infertile males with spermatogenic defects. J Reprod Immunol 2002;53:37-44
13. van der Ven K, Montag M, Peschka B, Leygraaf J, Schwanitz G, Haidl G, Krebs D, van der Ven H. Combined cytogenetic and Y chromosome microdeletion screening in males undergoing intracytoplasmic sperm injection. Mol Hum Reprod 1997;3:699-704
14. Wallace RW. DNA on a chip: serving up the genome for diagnostics and research. Mol Med Today 1997;3:384-9