Comparative in vitro activity of telithromycin against macrolide-resistant and -susceptible Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae

Journal of Antimicrobial Chemotherapy

Volumn 53, Issue 5, 2004, Pages 793-796

  Walsh, Fiona ^a   Carnegy, Francis ^a   Willcock, Joanne ^b   Amyes, Sebastian ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b Aventis Pharma Ltd   (United Kingdom)

Author keywords

Erm(B); Ketolides; Resistance

Indexed keywords

ANTIINFECTIVE AGENT; AZITHROMYCIN; CARBON DIOXIDE; CLINDAMYCIN; ERYTHROMYCIN; GEMIFLOXACIN; LINEZOLID; MACROLIDE; MOXIFLOXACIN; TELITHROMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENETICS; BACTERIAL STRAIN; BACTERIUM ISOLATION; CONTROLLED STUDY; DILUTION; HAEMOPHILUS INFLUENZAE; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; NONHUMAN; PATHOGENESIS; RESPIRATORY SYSTEM; STREPTOCOCCUS PNEUMONIAE; UNITED KINGDOM;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CARBON DIOXIDE; DRUG RESISTANCE, BACTERIAL; GENES, BACTERIAL; HAEMOPHILUS INFLUENZAE; HUMANS; KETOLIDES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MORAXELLA (BRANHAMELLA) CATARRHALIS; STREPTOCOCCUS PNEUMONIAE;

EID: 2442682929     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkh178     Document Type: Article

References (14)

1. Felmingham, D. (2002). Evolving resistance patterns in community-acquired respiratory tract pathogens: first results from the PROTEKT global surveillance study. Journal of Infection 44, 3-10.
2. Barry, A. L., Fuchs, P. C. & Brown, S. D. (1998). In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae. Antimicrobial Agents and Chemotherapy 42, 2138-40.
3. Wootton, M., Bowker, K. E., Janowska, A. et al. (1999). In vitro activity of HMR 3647 against Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and β-haemolytic streptococci. Journal of Antimicrobial Chemotherapy 44, 445-53.
4. Andrews, J. M. (2001). Determination of minimum inhibitory concentrations. Journal of Antimicrobial Chemotherapy 48, Suppl. S1, 5-16.
5. MacGowan, A. P. & Wise, R. (2001). Establishing MIC breakpoints and the interpretation of in vitro susceptibility tests. Journal of Antimicrobial Chemotherapy 48 Suppl. S1, 17-28.
6. Bearden, B. T., Neuhauser, M. M. & Garey, K. M. (2001). An oral ketolide for respiratory infections. Pharmacotherapy 21, 1204-22.
7. Sutcliffe, J., Grebe, T., Tait-Kamradt, A. et al. (1996). Detection of erythromycin-resistant determinants by PCR. Antimicrobial Agents and Chemotherapy 40, 2562-6.
8. Tait-Kamradt, A., Clancy, J., Cronan, M. et al. (1997). mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy 41, 2251-5.
9. Members of the SFM Antibiogram Committee. (2003). Comité de l'Antibiogramme de la Societé Française de Microbiologie Report 2003. International Journal of Antimicrobial Agents. 21 364-91.
10. Bemer-Melchoir, P., Juvin, M. E., Tassin, S. et al. (2000). In vitro activity of the new ketolide telithromycin compared with those of macrolides against Streptococcus pyogenes: influences of resistance mechanisms and methodological factors. Antimicrobial Agents and Chemotherapy 44, 2999-3002.
11. BSAC Working Party. (2003). BSAC Disc Diffusion Method for Antimicrobial Susceptibility Testing Version 2.1.4 [Online.] http://www.bsac.org.uk (5 March 2004, date last accessed).
12. Felmingham, D., Grüneberg, R. N. & the Alexander Project Group. (2000). The Alexander Project 1996-1997: latest susceptibility data from this international study of bacterial pathogens from community-acquired lower respiratory tract infections. Journal of Antimicrobial Chemotherapy 45, 191-203.
13. Johnson, A. P., Henwood, C. J., Tysall, L. et al. (2001). Activity of the ketolide telithromycin (HMR-3647) against erythromycin-susceptible and -resistant pneumococci isolated in the UK. International Journal of Antimicrobial Agents 18, 73-6.
14. Reinert, R. R., Wild, A., Appelbaum, A. et al. (2003). Ribosomal mutations conferring resistance to macrolides in Streptococcus pneumoniae clinical strains isolated in Germany. Antimicrobial Agents and Chemotherapy 47, 2319-22.