Heritability estimates for beta cell function and features of the insulin resistance syndrome in UK families with an increased susceptibility to Type 2 diabetes

Diabetologia

Volumn 47, Issue 4, 2004, Pages 732-738

  Mills, G W ^a,b   Avery, P J ^b   McCarthy, M I ^c,d   Hattersley, A T ^e   Levy, J C ^d   Hitman, G A ^f   Sampson, M ^g   Walker, M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF EXETER   (United Kingdom)

^f QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^g NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Genetic susceptibility; Heritability; Insulin resistance syndrome; Quantitative traits; Risk of Type 2 diabetes

Indexed keywords

GLUCOSE; INSULIN; LIPID;

ADULT; AGE; ANTHROPOMETRIC PARAMETERS; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CELL FUNCTION; CLINICAL OBSERVATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIET RESTRICTION; DISEASE PREDISPOSITION; FAMILY; FEMALE; GENETIC SUSCEPTIBILITY; GLUCOSE BLOOD LEVEL; HERITABILITY; HOMEOSTASIS; HUMAN; INSULIN SENSITIVITY; LIPID BLOOD LEVEL; MALE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; PANCREAS ISLET BETA CELL; PEDIGREE ANALYSIS; POPULATION RESEARCH; PRIORITY JOURNAL; PROGENY; SEX DIFFERENCE; SIBLING; STATISTICAL SIGNIFICANCE; SYSTOLIC BLOOD PRESSURE; UNITED KINGDOM;

ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE TOLERANCE TEST; GREAT BRITAIN; HOMEOSTASIS; HUMANS; INSULIN RESISTANCE; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; PANCREATIC FUNCTION TESTS; PEDIGREE; REGISTRIES;

EID: 2442670514     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-004-1338-2     Document Type: Article

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