Complete cycles of bloodstream trypanosome RNA editing in vitro

RNA

Volumn 10, Issue 6, 2004, Pages 914-920

  Halbig, Kari ^a   De Nova Ocampo, Monica ^a   Cruz Reyes, Jorge ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Bloodstream form; RNA editing; Trypanosoma brucei

Indexed keywords

GUIDE RNA; MESSENGER RNA; MITOCHONDRIAL RNA; URIDINE PHOSPHATE;

ARTICLE; CATALYSIS; DIAGNOSTIC VALUE; GENE DELETION; GENE INSERTION; IN VITRO STUDY; INSECT DEVELOPMENT; LIFE CYCLE; MAMMAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; REGULATORY MECHANISM; RNA EDITING; SPECIES COMPARISON; TRYPANOSOMA BRUCEI;

ANIMALS; MALE; RATS; RATS, WISTAR; RNA EDITING; RNA, PROTOZOAN; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS; TSETSE FLIES;

INSECTA; INSERTION SEQUENCES; KINETOPLASTIDA; MAMMALIA; PROTISTA; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 2442670275     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5157704     Document Type: Article

References (43)

1. Bhat, G.J., Souza, A.E., Feagin, J.E., and Stuart, K. 1992. Transcript-specific developmental regulation of polyadenylation in Trypanosoma brucei mitochondria. Mol. Biochem. Parasitol. 52: 231-240.
2. Blum, B., Bakalara, N., and Simpson, L. 1990. A model for RNA editing in kinetoplastid mitochondria: 'Guide' RNA molecules transcribed from maxicircle DNA provide the edited information. Cell 60: 189-198.
3. Burgess, M.L.K. and Stuart, K. 2000. Sequence bias in edited kineto-plastid RNAs. RNA 6: 1492-1497.
4. Byrne, E.M., Connell, G.J., and Simpson, L. 1996. Guide RNA-directed uridine insertion RNA editing in vitro. EMBO J. 15: 6758-6765.
5. Corell, R.A., Read, L.K., Riley, G.R., Nellissery, J.K., Allen, T.E., Kable, M.L., Wachal, M.D., Seiwert, D.S., Myler, P.J., and Stuart, K.D. 1996. Complexes from Trypanosoma brucei that exhibit deletion editing and other editing-associated properties. Mol. Cell. Biol. 16: 1410-1418.
6. Cruz-Reyes, J. and Sollner-Webb, B. 1996. Trypanosome U-deletional RNA editing involves gRNA-directed endonuclease cleavage, terminal U-exonuclease and RNA ligase activities. Proc. Natl. Acad. Sci. 93: 8901-8906.
7. Cruz-Reyes, J., Rusché, L., Piller, K., and Sollner-Webb, B. 1998a. Trypanosoma brucei RNA editing: Adenosine nucleotides inversely affect U deletion and U insertion reactions at mRNA cleavage. Mol. Cell 1: 401-409.
8. Cruz-Reyes, J., Rusché, L.N., and Sollner-Webb, B. 1998b. Trypanosoma brucei U insertion and U deletion activities co-purify with an enzymatic editing complex but are differentially optimized. Nucleic Acids Res. 26: 3634-3639.
9. Cruz-Reyes, J., Zhelonkina, A., Rusché, L., and Sollner-Webb, B. 2001. Trypanosome RNA editing: Simple guide RNA features enhance U deletion 100-fold. Mol. Cell. Biol. 21: 884-892.
10. Cruz-Reyes, J., Zhelonkina, A., Huang, C., and Sollner-Webb, B. 2002. Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes. Mol. Cell. Biol. 22: 4652-4660.
11. Doering, T.L., Raper, J., Buxbaum, L.U., Hart, G.W., and Englund, P.T. 1990. Biosynthesis of glycosyl phosphatidylinositol protein anchors. Methods 1: 288-296.
12. Domingo, G.J., Palazzo, S.S., Wang, B., Pannicucci, B., Salavati, R., and Stuart, K. 2003. Dyskinetoplastic Trypanosoma brucei contains functional editing complexes. Eukariot. Cell. 2: 569-577.
13. Gull, K. 2001. The biology of kinetoplastid parasites: Insights and challenges from genomics and post-genomics. Int. J. Parasitol. 31: 443-452.
14. Harris, M.E. and Hajduk, S.L. 1992. Kinetoplastid RNA editing: In vitro formation of cytochrome b gRNA-mRNA chimeras from synthetic substrate RNAs. Cell 20: 1091-1099.
15. Huang, C.E., Cruz-Reyes, J., Zhelonkina, A.G., O'Hearn, S., Wirtz, E., and Sollner-Webb, B. 2001. Roles for ligases in the RNA editing complex of Trypanosoma brucei: Band IV is needed for U-deletion and RNA repair. EMBO J. 20: 4694-4703.
16. Igo Jr., R.P., Lawson, S.D., and Stuart, K. 2002a. RNA sequence and base pairing effects on insertion editing in Trypanosoma brucei. Mol. Cell. Biol. 22: 1567-1576.
17. Igo Jr., R.P., Weston, D.S., Ernst, N.L., Panigrahi, A.K., Salavati, R., and Stuart, K. 2002b. Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editing. Eukaryot. Cell. 1: 112-118.
18. Kable, M.L., Seiwert, S.D., Heidmann, S., and Stuart, K. 1996. RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA. Science 273: 1189-1195.
19. Koslowsky, D.J. and Yahampath, G. 1997. Mitochondrial mRNA 3' cleavage/polyadenylation and RNA editing in Trypanosoma brucei are independent events. Mol. Biochem. Parasitol. 90: 81-94.
20. Lukes, J., Guilbride, D.L., Votypka, J., Zikova, A., Benne, R., and Englund, P.T. 2002. Kinetoplast DNA network: Evolution of an improbable structure. Eukaryot. Cell 4: 495-502.
21. Madison-Antenucci, S., Sabatini, R.S., Pollard, V.W., and Hajduk, S.L. 1998. Kinetoplastid RNA-editing-associated protein 1 (REAP-1): A novel editing complex protein with repetitive domains. EMBO J. 1: 6368-6376.
22. Madison-Antenucci, S., Grams, J., and Hajduk, S.L. 2002. Editing machines: The complexities of trypanosome RNA editing. Cell 108: 435-438.
23. McManus, M.T., Shimamura, M., Grams, J., and Hajduk, S.L. 2000. Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei. RNA 7: 167-175.
24. Michelotti, E.F., Harris, M.E., Adler, B., Torri, A.F., and Hajduk, S.L. 1992. Trypanosoma brucei mitochondrial ribosomal RNA synthesis, processing and developmentally regulated expression. Mol. Biochem. Parasitol. 54: 31-42.
25. Militello, K.T. and Read, L.K. 1999. Coordination of kRNA editing and polyadenylation in Trypanosoma brucei mitochondria: Complete editing is not required for long poly(A) tract addition. Nucleic Acids Res. 27: 1377-1385.
26. Pai, R.D., Oppegard, L.M., and Connell, G.J. 2003. Sequence and structural requirements for optimal guide RNA-directed insertional editing within Leishmania tarentolae. RNA 9469-9483.
27. Pelletier, M. and Read, L.K. 2003. RBP16 is a multifunctional gene regulatory protein involved in editing and stabilization of specific mitochondrial mRNAs in Trypanosoma brucei. RNA 9: 457-468.
28. Pollard, V.W., Harris, M.E., and Hajduk, S.L. 1992. Native mRNA editing complexes from Trypanosoma brucei mitochondria. EMBO J. 11: 4429-4438.
29. Priest, J.W. and Hajduk, S.L. 1994. Developmental regulation of mitochondrial biogenesis in Trypanosoma brucei. J. Bioenerg. Biomembr. 2: 179-191.
30. Read, L.K., Stankey, K.A., Fish, W.R., Muthiani, A.M., and Stuart, K. 1994. Developmental regulation of RNA editing and polyadenylation of four life cycle stages of Trypanosoma congolense. Mol. Biochem. Parasitol. 68: 297-306.
31. Rusché, L.N., Cruz-Reyes, J., Piller, K.J., and Sollner-Webb, B. 1997. Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria. EMBO J. 16: 4069-4081.
32. Rusché, L.N., Huang, C.E., Piller, K.J., Hemann, M., Wirtz, E., and Sollner-Webb, B. 2001. The two RNA ligases of the Trypanosoma brucei RNA editing complex: Cloning the essential band IV gene and identifying the band V gene. Mol. Cell. Biol. 21: 979-989.
33. Sabatini, R. and Hajduk, S.L. 1995. RNA ligase and its involvement in guide RNA/mRNA chimera formation. Evidence for a cleavage-ligation mechanism of Trypanosoma brucei mRNA editing. J. Biol. Chem. 270: 7233-7240.
34. Schnaufer, A., Panigrahi, A.K., Panicucci, B., Igo Jr., R.P., Salavati, R., and Stuart, K. 2001. An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science 291: 2159-2162.
35. Schnaufer, A., Lewis Ernst, N., Palazzo, S.S., O'Rear J., Salavati, R., and Stuart, K. 2003. Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol. Cell 12: 307-319.
36. Seiwert, S.D. and Stuart, K. 1994. RNA editing: Transfer of genetic information from gRNA to precursor mRNA in vitro. Science 266: 114-117.
37. Seiwert, S.D., Heidmann, S., and Stuart, K. 1996. Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing. Cell 84: 831-841.
38. Simpson, L., Aphasizhev, R., Gao, G., and Kang, X. 2004. Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion and U-deletion RNA editing. RNA 10: 159-170.
39. Sollner-Webb, B., Rusche, L.N., and Cruz-Reyes, J. 2001. Ribonuclease activities of trypanosome RNA editing complex directed to cleave specifically at a chosen site. Methods Enzymol. 341: 154-174.
40. Stuart, K. and Panigrahi, A.K. 2002. RNA editing: Complexity and complications. Mol. Microbiol. 45: 591-596.
41. Stuart, K., Allen, T.E., Heidmann, S., and Seiwert, S.D. 1997. RNA editing in kinetoplastid protozoa. Microbiol. Mol. Biol. Rev. 61: 105-120.
42. Vickerman, K. 1985. Developmental cycles and biology of pathogenic trypanosomes. Br. Med. Bull. 41m: 105-114.
43. Wirtz, E., Hoek M., and Cross, G.A.M. 1998. Regulated processive transcription of chromatin by T7 RNA polymerase in Trypanosoma brucei. Nucleic Acids Res. 26: 4626-4634.