Strategies for replacing lost cochlear hair cells

NeuroReport

Volumn 15, Issue 7, 2004, Pages 1089-1092

  Minoda, Ryosei ^a   Izumikawa, Masahiko ^a   Kawamoto, Kohei ^a   Raphael, Yehoash ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Adenovirus; BHLH; Cochlea; Deafness; Gene therapy; Hair cell; Stem cell

Indexed keywords

BIOCHEMICAL MARKER;

CELL BASED GENE THERAPY; CELL DIFFERENTIATION; CELL FUNCTION; CELL REGENERATION; CELL RENEWAL; CELL STRUCTURE; CELL TYPE; COCHLEA; CORTI ORGAN; EPITHELIUM; GENE INSERTION; HAIR CELL; HUMAN; MOSAICISM; NEUROEPITHELIUM; NONHUMAN; PERCEPTION DEAFNESS; PRIORITY JOURNAL; REVIEW; STEM CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; COCHLEA; HAIR CELLS; HEARING LOSS, SENSORINEURAL; HUMANS; TRANSCRIPTION FACTORS;

EID: 2442660101     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200405190-00001     Document Type: Review

References (42)

1. Chen P, Johnson JE, Zoghbi HY and Segil N. The role of Math1 in inner ear development: uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 2002; 129:2495-2505.
2. Lawoko-Kerali G, Rivolta MN and Holley M. Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear. J Comp Neurol 2002; 442:378-391.
3. Dong Y, Nakagawa T, Endo T, Kim TS, Iguchi F, Yamamoto N et al. Role of the F-box protein Skp2 in cell proliferation in the developing auditory system in mice. Neuroreport 2003; 14:759-761.
4. Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL et al. The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development 2003; 130:221-232.
5. Zine A, Van De Water TR and de Ribaupierre F. Notch signaling regulates the pattern of auditory hair cell differentiation in mammals. Development 2000; 127:3373-3383.
6. Ryan AF. Molecular studies of hair cell development and survival. Audiol Neurootol 2002; 7:138-140.
7. Liu M, Pereira FA, Price SD, Chu M, Shope C, Himes D et al. Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. Genes Dev 2000; 14:2839-2854.
8. Zine A, Aubert A, Qui J, Therianos S, Guillemot F, Kageyama R et al. Hes1 and Hes5 activities are required for the normal development of the hair cells in the mammalian inner ear. J Neurosci 2001; 21:4712-4720.
9. Lumpkin EA, Collison T, Parab P, Omer-Abdulla A, Haeberle M, Chen P et al. Math1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expr Patterns 2003; 3:389-395.
10. Brown NL, Patel S, Brzezinski J and Glaser T. Math5 is required for retinal ganglion cell and optic nerve formation. Development 2001; 128:2497-2508.
11. Vetter ML and Brown NL. The role of basic helix-loop-helix genes in vertebrate retinogenesis. Semin Cell Dev Biol 2001; 12:491-498.
12. Jensen J et al. Control of endodermal endocrine development by Hes-1. Nature Genet 2000; 24:36-44.
13. Novitch BG, Chen AI and Jessell TM. Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH represser Olig2. Neuron 2001; 31:773-789.
14. Zine A. Molecular mechanisms that regulate auditory hair-cell differentiation in the mammalian cochlea. Mol Neurobiol 2003; 27: 223-238.
15. Lewis J and Davies A. Planar cell polarity in the inner ear: how do hair cells acquire their oriented structure? J Neurobiol 2002; 53:190-201.
16. Stroeva OG and Mitashov VI. Retinal pigment epithelium: proliferation and differentiation during development and regeneration. Int Rev Cytol 1983; 83:221-293.
17. Ikegami Y, Mitsuda S and Araki M. Neural cell differentiation from retinal pigment epithelial cells of the newt: an organ culture model for the urodele retinal regeneration. J Neurobiol 2002; 50:209-220.
18. Forge A, Li L and Nevill G. Hair cell recovery in the vestibular sensory epithelia of mature guinea pigs. J Comp Neurol 1998; 397:69-88.
19. Cotanche DA. Structural recovery from sound and aminoglycoside damage in the avian cochlea. Audiol Neurootol 1999; 4:271-285.
20. Roberson DW, Kreig CS and Rubel EW. Light microscopic evidence that direct transdifferentiation gives rise to new hair cells in regenerating avian auditory epithelium. Audit Neurosci 1996; 2:195-205.
21. Adler HJ and Raphael Y. New hair cells arise from supporting cell conversion in the acoustically damaged chick inner ear (published erratum appears in Neurosci Lett 1996; 210:73). Neurosci Lett 1996; 205:17-20.
22. Raphael Y. Reorganization of the chick basilar papilla after acoustic trauma. J Comp Neurol 1993; 330:521-532.
23. Rivolta MN, Grix N, Lawlor P, Ashmore JF, Jagger DJ and Holley MC. Auditory hair cell precursors immortalized from the mammalian inner ear. Proc R Soc Lond B Biol Sci 1998; 265:1595-1603.
24. Barald KF, Lindberg KH, Hardiman K, Kavka AI, Lewis JE, Victor JC et al. Immortalized cell lines from embryonic avian and murine otocysts: tools for molecular studies of the developing inner ear. Int J Dev Neurosci 1997; 15:523-540.
25. Li H, Roblin G, Liu H and Heller S. Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc Natl Acad Sci USA 2003; 100:13495-13500.
26. Li H, Liu H and Heller S. Pluripotent stem cells from the adult mouse inner ear. Nature Med 2003; 9:1293-1299.
27. Dazert S, Aletsee C, Brors D, Sudhoff H, Ryan AF and Muller AM. Regeneration of inner ear cells from stem cell precursors - a future concept of hearing rehabilitation? DNA Cell Biol 2003; 22:565-570.
28. Parker MA and Cotanche DA. The potential use of stem cells for cochlear repair. Audiol Neurootol 2004; 9:72-80.
29. Zheng JL and Gao WQ. Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nature Neurosci 2000; 3:580-586.
30. Shou J, Zheng JL and Gao WQ. Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1. Mol Cell Neurosci 2003; 23:169-179.
31. Costantini LC, Bakowska JC, Breakefield XO and Isacson O. Gene therapy in the CNS. Gene Ther 2000; 7:93-109.
32. Walsh CE. Gene therapy for the hemophilias. Curr Opin Pediatr 2002; 14:12-16.
33. Hsich G, Sena-Esteves M and Breakefield XO. Critical issues in gene therapy for neurologic disease. Hum Gene Ther 2002; 13:579-604.
34. Balicki D and Beutler E. Gene therapy of human disease. Medicine (Baltimore) 2002; 81:69-86.
35. Ishimoto S, Kawamoto K, Kanzaki S and Raphael Y. Gene transfer into supporting cells of the organ of Corti. Hear Res 2002; 173: 187-197.
36. Brough DE, Hsu C, Kúlesa VA, Lee GM, Cantolopo LJ, Lizonova A et al. Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo. J Virol 1997; 71:9206-9213.
37. Kawamoto K, Ishimoto S, Minoda R, Brough DE and Raphael Y. Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo. J Neurosci 2003; 23:4395-4400.
38. Stone JS, Oesterle EC and Rubel EW. Recent insights into regeneration of auditory and vestibular hair cells. Curr Opin Neurol 1998; 11:17-24.
39. Rubel EW and Stone JS. Stimulating hair cell regeneration: on a wing and a prayer. Nature Med 1996; 2:1082-1083.
40. Corwin JT and Oberholtzer JC. Fish n' chicks: model recipes for hair-cell regeneration? Neuron 1997; 19:951-954.
41. Raphael Y. Cochlear pathology, sensory cell death and regeneration. Br Med Bull 2002; 63:25-38.
42. Bermingham-McDonogh O and Rubel EW. Hair cell regeneration: winging our way towards a sound future. Curr Opin Neurobiol 2003; 13:119-126.