Abrin poisoning

Toxicological Reviews

Volumn 22, Issue 3, 2003, Pages 137-142

  Dickers, Kirsten J ^a   Bradberry, Sally M ^a   Rice, Paul ^b   Griffiths, Gareth D ^b   Vale, J Allister ^a  

^a CITY HOSPITAL   (United Kingdom)

^b DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABRIN; ABRUS PRECATORIUS EXTRACT; ACTIVATED CARBON; ASCORBIC ACID; CASTOR OIL; CHEMICAL WARFARE AGENT; PLANT TOXIN; RICIN; RICIN ANTIBODY; TOXOID;

ABRUS; ACUTE PANCREATITIS; ASCITES; BEAN; CAPILLARY PERMEABILITY; CELL DAMAGE; CELL DEATH; DIABETES MELLITUS; EDEMA; ENDOTHELIUM CELL; ERYTHROCYTE AGGREGATION; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL TOXICITY; HUMAN; HYPOCALCEMIA; INGESTION; INTOXICATION; LETHAL DOSE; LUNG EDEMA; NEUROTOXICITY; NONHUMAN; PLANT SEED; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; REVIEW; TOXICOKINETICS; VASCULAR LESION; WEAPON;

ABRIN; ADOLESCENT; ANIMALS; CHEMICAL WARFARE; HUMANS; MALE; TISSUE DISTRIBUTION;

ABRUS; ABRUS PRECATORIUS; CASTOR; PHASEOLUS (ANGIOSPERM);

EID: 2442646397     PISSN: 11762551     EISSN: None     Source Type: Journal    
DOI: 10.2165/00139709-200322030-00002     Document Type: Review

References (39)

1. Locock RA. Abrus precatorious: precatory bean. Can Pharm J 1992; 125: 502-14
2. University of Warwick. Molecular structure of abrin [online]. Available from URL: http://www.bio.warwick.ac.uk/toxin/molecules/abrin.html [Accessed 2003 Sep 1]
3. Sandvig K, Olsnes S, Pihl A. Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells. J Biol Chem 1976; 251: 3977-84
4. Niyogi SK, Rieders F. Toxicity studies with fractions from Abrus precatorius seed kernels. Toxicon 1969; 7: 211-6
5. Olsnes S. Toxic and nontoxic lectins from Abrus precatorius. Methods Enzymol 1978; 50: 323-30
6. Olsnes S. Abrin and ricin: structure and mechanism of action of two toxic lectins. Bull Inst Pasteur 1976; 74: 85-99
7. Lin J-Y, Lee T-C, Hu S-T, et al. Isolation of four isotoxic proteins and one agglutinin from jequiriti bean (Abrus precatorius). Toxicon 1981; 19: 41-51
8. Olsnes S, Refsnes K, Pihl A. Mechanism of action of the toxic lectins abrin and ricin. Nature 1974; 249: 627-31
9. Hughes JN, Lindsay CD, Griffiths GD. Morphology of ricin and abrin exposed endothelial cells is consistent with apoptotic cell death. Hum Exp Toxicol 1996; 15: 443-51
10. Griffiths GD, Leek MD, Gee DJ. The toxic plant proteins ricin and abrin induce apoptotic changes in mammalian lymphoid tissues and intestine. J Pathol 1987; 151: 221-9
11. Griffiths GD, Lindsay CD, Upshall DG. Examination of the toxicity of several protein toxins of plant origin using bovine pulmonary endothelial cells. Toxicology 1994; 90: 11-27
12. Baluna R, Rizo J, Gordon BE, et al. Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome. Proc Natl Acad Sci U S A 1999; 96: 3957-62
13. Deshpande VR, Dubey PN, Joshi Rao MK. Toxicity of Abrus precatorius. Indian J Med Sci 1961; 15: 195-7
14. Frohne D, Schmoldt A, Pfänder HJ. Die Paternotererbse: keineswegs harmlos. Dtsch Apoth Ztg 1984; 124: 2109-13
15. Toxicity of jequirity beans. JAMA 1955; 157: 779
16. Lin J-Y, Kao C-L, Tung T-C. Study on the effect of tryptic digestion on the toxicity of abrin. J Formos Med Assoc 1970; 69: 61-3
17. Fodstad Ø, Olsnes S, Pihl A. Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice. Br J Cancer 1916; 34: 418-25
18. 131-labeled abrin in vivo. Toxicon 1970; 8: 197-201
19. Houston LL. Protection of mice from ricin poisoning by treatment with antibodies directed against ricin. J Toxicol Clin Toxicol 1982; 19: 385-9
20. Davis JH. Abrus precatorius (rosary pea). The most common lethal plant poison. J Florida Med Assoc 1978; 65: 188-91
21. Kinamore PA, Jaeger RW, de Castro FJ. Abrus and ricinus ingestion: management of three cases. J Toxicol Clin Toxicol 1980; 17: 401-5
22. Swanson-Biearman B, Dean BS, Krenzelok EP. Failure of whole bowel irrigation to decontaminate the GI tract following massive jequirity bean ingestion [abstract]. Vet Hum Toxicol 1992; 34: 352
23. Hart M. Hazards to health: jequirity-bean poisoning. N Engl J Med 1963; 268: 885-6
24. Fernando C. Poisoning due to Abrus precatorius (jequirity bean). Anaesthesia 2001; 56: 1178-80
25. Kobert R. Lehrbuch der Intoxikationen. 2nd ed. Stuttgart: Ferdinand Enke, 1906
26. Guggisberg M. A propos d'une curieuse intoxication par des grains de chapelet (Abrus precatorius). Rev Med Suisse Romande 1968; 88: 206-8
27. Byam W, Archibald RG, editors. The practice of medicine in the tropics. London: Henry Frowde and Hodder & Stoughton, 1921
28. Gill DM. Bacterial toxins: a table of lethal amounts. Microbiol Rev 1982; 46: 86-94
29. Fodstad Ø, Johannessen JV, Schjerven L, et al. Toxicity of abrin and ricin in mice and dogs. J Toxicol Environ Health 1979; 5: 1073-84
30. el-Shabrawy OA, el-Gengaihi S, Ali Ibrahim N. Toxicity and teratogenicity of abrin. Egyptian J Vet Sci 1987; 24: 135-42
31. Routh BC, Lahiri SC. Some actions of the seeds of Abrus precatorius. Bull Calcutta School Trop Med 1971; 19: 46-7
32. Lin J-Y, Chen C-C, Lin L-T, et al. Studies on the toxic action of abrin. J Formosan Med Assoc 1969; 68: 322-4
33. Niyogi SK. Elevation of enzyme levels in serum due to Abrus precatorius (jequirity bean) poisoning. Toxicon 1977; 15: 577-80
34. Griffiths GD, Rice P, Allenby AC, et al. Inhalation toxicology and histopathology of ricin and abrin toxins. Inhal Toxicol 1995; 7: 269-88
35. Grant WM, Schuman JS. Toxicology of the eye: effects on the eyes and visual system from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. 4th ed. Springfield (IL): Charles C. Thomas, 1993
36. Godal A, Olsnes S, Pihl A. Radioimmunoassays of abrin and ricin in blood. J Toxicol Environ Health 1981; 8: 409-17
37. Griffiths GD, Lindsay CD, Allenby AC, et al. Protection against inhalation toxicity of ricin and abrin by immunisation. Hum Exp Toxicol 1995; 14: 155-64
38. Clark CE, Keplinger JL, Riddle MR, et al. Time dependency of ascorbate compound administration to alter the mean survival time of abrin intoxication [abstract]. Fed Proc 1981; 40: 865
39. Poli MA, Rivera VR, Pitt ML, et al. Aerosolized specific antibody protects mice from lung injury associated with aerosolized ricin exposure. Toxicon 1996; 34: 1037-44