Inhibitory effect of a novel bisphosphonate, TRK-530, on dental calculus formation in rats

Journal of Periodontology

Volumn 75, Issue 4, 2004, Pages 537-545

  Haq Sikder, M N ^a   Itoh, Masatoshi ^b   Iwatsuki, Naofumi ^a   Shinoda, Hisashi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TORAY INDUSTRIES INC   (Japan)

Author keywords

Animal studies; Bisphosphonates therapeutic use; Dental calculus prevention and control

Indexed keywords

[4 (METHYLTHIO)PHENYLTHIO]METHANE BISPHOSPHNIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM PHOSPHATE; DRINKING WATER; TRK 530; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; DRUG ABSORPTION; DRUG DOSE REGIMEN; DRUG MECHANISM; IN VITRO STUDY; INTESTINE ABSORPTION; MALE; NONHUMAN; OSTEOLYSIS; PATHOGENESIS; PRECIPITATION; RAT; TOOTH CALCULUS; X RAY DIFFRACTION;

ADMINISTRATION, TOPICAL; ANALYSIS OF VARIANCE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DENTAL CALCULUS; DIPHOSPHONATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; DURAPATITE; MALE; PRECIPITATION; RATS; RATS, WISTAR; WATER;

EID: 2442619114     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2004.75.4.537     Document Type: Article

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