The epidermal lamellar body: A fascinating secretory organelle

Journal of Investigative Dermatology

Volumn 122, Issue 5, 2004, Pages

  Fartasch, Manigé ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

SKIN LIPID;

CELL ORGANELLE; EDITORIAL; EPIDERMIS; HUMAN; LAMELLAR BODY; NONHUMAN; PRIORITY JOURNAL; SKIN CELL; SKIN PERMEABILITY; STRATUM CORNEUM;

EID: 2442618883     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.22541.x     Document Type: Editorial

References (12)

1. Elias PM, Cullander C, Mauro T, Rassner U, Komuves L, Brown BE, Menon GK: The secretory granular cell: The outermost granular cell as a specialized secretory cell. J Investig Dermatol Symp Proc 3:87-100, 1998
2. Elias PM, Fartasch M, Crumrine D, Behne M, Uchida Y, Holleran WM: Origin of the corneocyte lipid envelope (CLE): Observation in harlequin ichthyosis and cultured human keratinocytes. J Invest Dermatol 115:765-769, 2000
3. Elias PM, Feingold KR (ed): Cutaneous Barrier Function. New York: Marcel Dekker, 2004
4. Fartasch M, Bassukas ID, Diepgen TL: Disturbed extruding mechnism of lamellar bodies in dry non-eczematous skin of atopics. Br J Dermatol 221-227, 1992
5. Fartasch M, Williams ML, Elias PM: Altered lamellar body secretion and stratum corneum membrane structure in Netherton syndrome: Differentiation from other infantile erythrodermas and pathogenic implications. Arch Dermatol 135:823-632, 1999
6. Grayson S, Johnson-Winegar AG, Wintroub BU, Isseroff RR, Epstein EH, Elias PM: Lamellar body-enriched fractions from neonatal mice: Preparative techniques and partial characterization. J Invest Dermatol 85:289-294, 1985
7. Madison KC: Barrier function of the skin: "La Raison d'Etre" of the epidermis. J Invest Dermatol 121:231-241, 2003
8. Menon GK, Ghadially R, Williams ML, Elias PM: Lamellar bodies as delivery systems of hydrolytic enzymes: Implications for normal and abnormal desquamation. Br J Dermatol 126:337-345, 1992
9. Norlen L: Skin barrier formation: The membrane folding model. J Invest Dermatol 117:823-829, 2001
10. Oren A, Ganz T, Liu L, Meerloo T: In human epidermis, beta-defensin 2 is packaged in lamellar bodies. Exp Mol Path 74:180-182, 2003
11. Sando GN, Zhu H, Weis JM, Richman JT, Wertz PW, Madison KC: Caveolin Expression and localization in human keratinocytes suggest a role in lamellar granule biogenesis. J Invest Dermatol 120:531-541, 2003
12. Wolff K, Holubar K: Keratinosomes as epidermal lysosomes. Arch Klin Exp Dermatol 231:1-19, 1967