메뉴 건너뛰기




Volumn 14, Issue 12, 2004, Pages 3103-3107

Conformationally restricted analogs of deoxynegamycin

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DEOXYNEGAMYCIN; UNCLASSIFIED DRUG;

EID: 2442600065     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.04.036     Document Type: Article
Times cited : (17)

References (35)
  • 29
    • 2442519020 scopus 로고    scopus 로고
    • note
    • 2. The stereochemistry of these analogs at cyclopropane juncture cannot be assigned by NMR due to the presence of rotomers
  • 32
    • 2442585122 scopus 로고    scopus 로고
    • note
    • 5 cfu/mL
  • 33
    • 2442417319 scopus 로고    scopus 로고
    • note
    • Inhibition of protein synthesis was measured with a cell-free transcription/translation coupled assay (E. coli S30 Extract System, Promega, Madison, WI) using pGEMbgal as a DNA template. Compounds were pre-incubated with the reaction mixture for 10 min prior to the addition of template. After 1 h incubation, ONPG was added and β-galactosidase activity was monitored at 420 nm
  • 34
    • 2442591384 scopus 로고    scopus 로고
    • note
    • 50=2.3 mg/kg)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.