Understanding experimental biology of skin equivalent: From laboratory to clinical use in patients with burns and chronic wounds

American Journal of Surgery

Volumn 187, Issue 5 SUPPL. 1, 2004, Pages S29-S33

  Ehrlich, H Paul ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 3; TRANSFORMING GROWTH FACTOR BETA; TRYPSIN;

BACTERIOLOGY; BASEMENT MEMBRANE; BIOLOGY; BURN; CELL CULTURE; CELL DIFFERENTIATION; CELL POPULATION; CELL VIABILITY; DONOR SITE; EPIDERMIS CELL; FIBROBLAST; HUMAN; KERATINOCYTE; POLYMERIZATION; PREPUCE; PRIORITY JOURNAL; REVIEW; SKIN AUTOGRAFT; SKIN GRAFT; SURGICAL TECHNIQUE; TISSUE CULTURE; WOUND CARE; WOUND CLOSURE;

EID: 2442595109     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9610(03)00301-5     Document Type: Article

References (15)

1. Burke J.F., Bondoc C.C., Quinby W.C. Primary burn excision and immediate grafting a method shortening illness. J Trauma. 14:1974;389-395
2. Burke J.F. Observations on the development and clinical use of artificial skin - an attempt to employ regeneration rather than scar formation in wound healing. Jpn J Surg. 17:1987;431-438
3. Burke J.F., Yannas I.V., Quinby W.C. Jr, Bondoc C.C., Jung W.K. Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg. 194:1981;413-428
4. Gallico G.G. III, O'Connor N.E., Compton C.C., Kehinde O., Green H. Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med. 311:1984;448-451
5. Bell E., Ehrlich H.P., Buttle D.J., Nakatsuji T. Living tissue formed in vitro and accepted as skin-equivalent tissue of full thickness. Science. 211:1981;1052-1054
6. Bell E., Ivarsson B., Merrill C. Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc Natl Acad Sci U S A. 76:1979;1274-1278
7. Ehrlich H.P., Rajaratnam J.B. Cell locomotion forces versus cell contraction forces for collagen lattice contraction an in vitro model of wound contraction. Tissue Cell. 22:1990;407-417
8. Ehrlich H.P., Rittenberg T. Differences in the mechanism for high- versus moderate-density fibroblast-populated collagen lattice contraction. J Cell Physiol. 185:2000;432-439
9. Ehrlich H.P., Buttle D.J., Bernanke D.H. Physiological variables affecting collagen lattice contraction by human dermal fibroblasts. Exp Mol Pathol. 50:1989;220-229
10. Ehrlich H.P., Rockwell W.B., Cornwell T.L., Rajaratnam J.B. Demonstration of a direct role for myosin light chain kinase in fibroblast-populated collagen lattice contraction. J Cell Physiol. 146:1991;1-7
11. Harris A.K., Wild P., Stopak D. Silicone rubber substrata a new wrinkle in the study of cell locomotion. Science. 208:1980;177-179
12. Gullberg D., Tingstrom A., Thuresson A.C., et al. Beta 1 integrin-mediated collagen gel contraction is stimulated by PDGF. Exp Cell Res. 186:1990;264-272
13. Montesano R., Orci L. Transforming growth factor beta stimulates collagen-matrix contraction by fibroblasts implications for wound healing. Proc Natl Acad Sci U S A. 85:1988;4894-4897
14. Ehrlich H.P. The modulation of contraction of fibroblast populated collagen lattices by types I, II, and III collagen. Tissue Cell. 20:1988;47-50
15. Rittenberg T., Ehrlich H.P. Free fatty acids and dialyzed serum alterations of fibroblast populated collagen lattice contraction. Tissue Cell. 24:1992;243-251