An efficient and highly selective deprotection of N-Fmoc-α-amino acid and lipophilic N-Fmoc-dipeptide methyl esters with aluminium trichloride and N,N-dimethylaniline

Journal of Peptide Research

Volumn 63, Issue 4, 2004, Pages 383-387

  Di Gioia, M L ^a   Leggio, A ^a   Le Pera, A ^a   Siciliano, C ^a   Sindona, G ^a   Liguori, A ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Aluminium trichloride; Amino acids; Dipeptides; Fmoc group; Methyl esters; N,N dimethylaniline

Indexed keywords

ALUMINUM; AMINO ACID DERIVATIVE; CARBOXYL GROUP; CHLORIDE; ESTER DERIVATIVE; METHYL GROUP; N,N DIMETHYLANILINE; NITROGEN DERIVATIVE; PEPTIDE DERIVATIVE;

ARTICLE; CHIRALITY; DEPROTECTION REACTION; LIPOPHILICITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; OPTICS; PRIORITY JOURNAL; PROTEIN PURIFICATION; SYSTEM ANALYSIS;

ALUMINUM COMPOUNDS; AMINO ACIDS; ANILINE COMPOUNDS; CHLORIDES; DIPEPTIDES; ESTERS; FLUORENES; STEREOISOMERISM;

EID: 2442586703     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2004.00104.x     Document Type: Article

References (10)

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9. 2 cleavage of esters and lactones. J. Org. Chem. 13, 2605-2610.
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