Randomized comparison of granulocyte colony-stimulating factor versus granulocyte-macrophage colony-stimulating factor plus intensive chemotherapy for peripheral blood stem cell mobilization and autologous transplantation in multiple myeloma

Biology of Blood and Marrow Transplantation

Volumn 10, Issue 6, 2004, Pages 395-404

  Arora, Mukta ^a   Burns, Linda J ^a   Barker, Juliet N ^a   Miller, Jeffrey S ^a   Defor, Todd E ^a   Olujohungbe, Adebayo B ^a   Weisdorf, Daniel J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Autologous PBSC transplantation; Multiple myeloma; Randomized clinical trial

Indexed keywords

ALKYLATING AGENT; ALPHA INTERFERON; CD34 ANTIGEN; CIPROFLOXACIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOXANTRONE; PENICILLIN G;

ADULT; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CANCER COMBINATION CHEMOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CAUSE OF DEATH; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG RESPONSE; ELECTROLYTE DISTURBANCE; FEMALE; FEVER; FLU LIKE SYNDROME; HEADACHE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; INFECTION; INFECTION PREVENTION; LEUKAPHERESIS; LYMPHOCYTE COUNT; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; NAUSEA AND VOMITING; NEUTROPHIL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; STEM CELL MOBILIZATION; THROMBOCYTE; THROMBOCYTOPENIA; TREATMENT OUTCOME; WHOLE BODY RADIATION;

ADULT; ANTIGENS, CD34; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; FEMALE; GRAFT SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; MALE; MIDDLE AGED; MULTIPLE MYELOMA; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; REMISSION INDUCTION; SURVIVAL ANALYSIS; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 2442582965     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbmt.2004.02.001     Document Type: Article

References (13)

1. Attal M. Harousseau J.L. Stoppa A.M. et al. A prospective randomized trial of autologous transplantation and chemotherapy in multiple myeloma N Engl J Med. 335 1996 91-97
2. Bjorkstrand B. European Group for Blood and Marrow Transplantation Registry studies in multiple myeloma Semin Hematol. 38 2001 219-225
3. 2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial Blood 99 2002 731-735
4. Barlogie B. Jagannath S. Desikan K.R. Total therapy with tandem transplants for newly diagnosed multiple myeloma Blood 93 1999 55-65
5. Attal M. Harousseau J.-L. Facon T. et al. Double autologous transplantation improves survival of multiple myeloma patients: final analysis of a prospective randomized study of the Intergroupe Francophone du Myelome (IFM 94) Blood 100 2002 7a
6. Tricot G. Spencer T. Sawyer J. et al. Predicting long term (> or = 5 years) event free survival in multiple myeloma patients following planned tandem autotransplants Br J Haematol. 116 2002 211-217
7. Kaplan E.L. Meier P. Nonparametric estimation from incomplete observations J Am Stat Assoc. 53 1958 457-481
8. Cox D.R. Regression models and life tables J R Stat Soc B. 34 1972 187-220
9. Lin D.Y. Non-parametric inference for cumulative incidence functions in competing risks studies Stat Med. 16 1997 901-910
10. Desikan R. Barlogie B. Sawyer J. et al. Results of high-dose therapy for 1000 patients with multiple myeloma: durable complete remissions and superior survival in the absence of chromosome 13 abnormalities Blood 95 2000 4008-4010
11. Child J.A. Morgan G.J. Davies F.E. et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma N Engl J Med. 348 2003 1875-1883
12. Bjorkstrand B. Svensson H. Goldschmidt H. Alpha interferon maintenance treatment is associated with improved survival after high-dose treatment and autologous stem cell transplantation in patients with multiple myeloma: a retrospective registry study from the European Group for Blood and Marrow Transplantation (EBMT) Bone Marrow Transplant 27 2001 511-515
13. Toor A.A. van Burik J.A. Weisdorf D.J. Infections during mobilizing chemotherapy and following autologous stem cell transplantation Bone Marrow Transplant 28 2001 1129-1134