Further Insights into Quinone Cofactor Biogenesis: Probing the Role of mauG in Methylamine Dehydrogenase Tryptophan Tryptophylquinone Formation

Biochemistry

Volumn 43, Issue 18, 2004, Pages 5494-5502

  Pearson, Arwen R ^a   De La Mora Rey, Teresa ^a   Graichen, M Elizabeth ^b   Wang, Yongting ^b   Jones, Limei H ^b   Marimanikkupam, Sudha ^a   Agger, Sean A ^a   Grimsrud, Paul A ^a   Davidson, Victor L ^b   Wilmot, Carrie M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; ELECTROPHORESIS; GENETIC ENGINEERING; HYDROXYLATION;

BIOGENESIS; MUTANTS; MUTATION;

BIOCHEMISTRY;

AMINE DEHYDROGENASE; CYTOCHROME; CYTOCHROME C PEROXIDASE; HEME DERIVATIVE; HISTIDINE; POLYPEPTIDE; QUINONE COFACTOR; QUINONE DERIVATIVE; TRYPTOPHAN DERIVATIVE; TRYPTOPHAN TRYPTOPHYLQUINONE; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CHEMICAL REACTION KINETICS; COVALENT BOND; CROSS LINKING; ELECTROPHORESIS; GENE FUNCTION; GENE MUTATION; MASS SPECTROMETRY; NONHUMAN; PARACOCCUS DENITRIFICANS; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; CHYMOTRYPSIN; COENZYMES; CYTOCHROME-C PEROXIDASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HISTIDINE; HYDROLYSIS; INDOLEQUINONES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PARACOCCUS DENITRIFICANS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRYPSIN; TRYPTOPHAN; VALINE;

PARACOCCUS DENITRIFICANS;

EID: 2442582496     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049863l     Document Type: Article

References (23)

1. van der Palen, C. J., Slotboom, D. J., Jongejan, L., Reijnders, W. N., Harms, N., Duine, J. A., and van Spanning, R. J. (1995) Mutational analysis of mau genes involved in methylamine metabolism in Paracoccus denitrificans, Eur. J. Biochem. 230, 860-871.
2. Davidson, V. L. (2001) Pyrroloquinoline quinone (PQQ) from methanol dehydrogenase and tryptophan tryptophylquinone (TTQ) from methylamine dehydrogenase, Adv. Protein Chem. 58, 95-140.
3. Husain, M., and Davidson, V. L. (1985) An inducible periplasmic blue copper protein from Paracoccus denitrificans. Purification, properties, and physiological role, J. Biol. Chem. 260, 14626-14629.
4. Davidson, V. L., and Kumar, M. A. (1989) Cytochrome c-550 mediates electron transfer from inducible periplasmic c-type cytochromes to the cytoplasmic membrane of Paracoccus denitrificans, FEBS Lett. 245, 271-273.
5. Husain, M., and Davidson, V. L. (1986) Characterization of two inducible periplasmic c-type cytochromes from Paracoccus denitrificans, J. Biol. Chem. 261, 8577-8580.
6. Schwartz, B., and Klinman, J. P. (2001) Mechanisms of biosynthesis of protein-derived redox cofactors, Vitam. Horm. 61, 219-239.
7. Okeley, N. M., and van der Donk, W. A. (2000) Novel cofactors via posttranslational modifications of enzyme active sites, Chem. Biol. 7, R159-171.
8. Cai, D., and Klinman, J. P. (1994) Evidence of a self-catalytic mechanism of 2,4,5-trihydroxyphenylalanine quinone biogenesis in yeast copper amine oxidase, J. Biol. Chem. 269, 32039-32042.
9. Ruggiero, C. E., Smith, J. A., Tanizawa, K., and Dooley, D. M. (1997) Mechanistic studies of topa quinone biogenesis in phenylethylamine oxidase, Biochemistry 36, 1953-1959.
10. Matsuzaki, R., Fukui, T., Sato, H., Ozaki, Y., and Tanizawa, K. (1994) Generation of the topa quinone cofactor in bacterial monoamine oxidase by cupric ion-dependent autooxidation of a specific tyrosyl residue, FEBS Lett. 351, 360-364.
11. McIntire, W. S., Wemmer, D. E., Chistoserdov, A., and Lidstrom, M. E. (1991) A new cofactor in a prokaryotic enzyme: tryptophan tryptophylquinone as the redox prosthetic group in methylamine dehydrogenase, Science 252, 817-824.
12. Pearson, A. R., Jones, L. H., Higgins, L., Ashcroft, A. E., Wilmot, C. M., and Davidson, V. L. (2003) Understanding quinone cofactor biogenesis in methylamine dehydrogenase through novel cofactor generation, Biochemistry 42, 3224-3230.
13. Chistoserdov, A. Y., Boyd, J., Mathews, F. S., and Lidstrom, M. E. (1992) The genetic organization of the mau gene cluster of the facultative autotroph Paracoccus denitrificans, Biochem. Biophys. Res. Commun. 184, 1181-1189.
14. Chistoserdov, A. Y., Chistoserdova, L. V., McIntire, W. S., and Lidstrom, M. E. (1994) Genetic organization of the mau gene cluster in Methylobacterium extorquens AMI: complete nucleotide sequence and generation and characteristics of mau mutants, J. Bacteriol. 176, 4052-4065.
15. van der Palen, C. J., Reijnders, W. N., de Vries, S., Duine, J. A., and van Spanning, R. J. (1997) MauE and MauD proteins are essential in methylamine metabolism of Paracoccus denitrificans, Antonie van Leeuwenhoek 72, 219-228.
16. Wang, Y., Graichen, M. E., Liu, A., Pearson, A. R., Wilmot, C. M., and Davidson, V. L. (2003) MauG, a novel dibeme protein required for tryptophan tryptophylquinone biogenesis, Biochemistry 42, 7318-7325.
17. Graichen, M. E., Jones, L. H., Sharma, B. V., van Spanning, R. J., Hosler, J. P., and Davidson, V. L. (1999) Heterologous expression of correctly assembled methylamine dehydrogenase in Rhodobacter sphaeroides, J. Bacteriol. 181, 4216-4222.
18. Zhu, Z., Jones, L. H., Graichen, M. E., and Davidson, V. L. (2000) Molecular basis for complex formation between methylamine dehydrogenase and amicyanin revealed by inverse mutagenesis of an interprotein salt bridge, Biochemistry 39, 8830-8836.
19. Mather, M. W., McReynolds, L. M., and Yu, C. A. (1995) An enhanced broad-host-range vector for gram-negative bacteria: avoiding tetracycline phototoxicity during the growth of photosynthetic bacteria, Gene 156, 85-88.
20. Davidson, V. L. (1990) Methylamine dehydrogenases from methylotrophic bacteria, Methods Enzymol. 188, 241-246.
21. Davidson, V. L., and Jones, L. H. (1992) Cofactor-directed inactivation by nucleophilic amines of the quinoprotein methylamine dehydrogenase from Paracoccus denitrificans, Biochim. Biophys. Acta 1121, 104-110.
22. Davidson, V. L., and Sun, D. (2002) Lysozyme-osmotic shock methods for localization of periplasmic redox proteins in bacteria, Methods Enzymol. 353, 121-130.
23. Simon, R., Priefer, U., and Puhler, A. (1983) A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria, Bio/Technology 1, 784-791.