Relationship between Differentiation-inducing Activity and Hypercalcemic Activity of Hexafluorotrihydroxyvitamin D3 Derivatives

Anticancer Research

Volumn 24, Issue 2 B, 2004, Pages 683-689

  Unten, Senwa ^a   Ishihara, Mariko ^a   Sakagami, Hiroshi ^a  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Differentiation; Hexafluorotrihydroxyvitamin D3 derivatives; Hydrophobicity; Hypercalcemic activity; Log P; Structure activity relationship

Indexed keywords

24 HOMO 26,26,26,27,27,27 HEXAFLUORO 1,24,25 TRIHYDROXYCOLECALCIFEROL; COLECALCIFEROL DERIVATIVE; DD 003; DD 004; DD 005; DD 006; DD 007; DD 008; DD 009; DD 010; DD 011; DD 014; DD 015; HEXAFLUOROTRIHYDROXYVITAMIN D3 DERIVATIVE; MVD 1235; MVD 1400; MVD 3400; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM BLOOD LEVEL; CELL DIFFERENTIATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG STRUCTURE; FLUORINATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; ISOMERISM; LEUKEMIA CELL LINE; MALE; NONHUMAN; NUDE MOUSE; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELL DIFFERENTIATION; CHOLECALCIFEROL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HT29 CELLS; HUMANS; HYDROCARBONS, FLUORINATED; HYPERCALCEMIA; MALE; MICE; RATS; RATS, WISTAR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 2442547710     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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