Neuroendocrine Control of Larval Ecdysis Behavior in Drosophila: Complex Regulation by Partially Redundant Neuropeptides

Journal of Neuroscience

Volumn 24, Issue 17, 2004, Pages 4283-4292

  Clark, Anthony C ^a,b   Del Campo, Marta L ^a,c   Ewer, John ^a  

^a Department of Obstetrics Gynecology   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BINGHAMTON UNIVERSITY   (United States)

Author keywords

CCAP; cGMP; Ecdysis triggering hormone; Eclosion hormone; Molt; Neurohormone; Neurosecretion

Indexed keywords

CRUSTACEAN CARDIOACTIVE PEPTIDE; CYCLIC GMP; ECDYSIS TRIGGERING HORMONE; ECLOSION HORMONE; NEUROHORMONE; NEUROPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CUTICLE; DROSOPHILA; INSECT; LARVA; MOLTING; NEUROENDOCRINE SYSTEM; NEUROSECRETION; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; REGULATORY MECHANISM; STEREOTYPY; TRACHEA; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BEHAVIOR, ANIMAL; DROSOPHILA MELANOGASTER; INSECT HORMONES; LARVA; MOLTING; NEUROPEPTIDES; NEUROSECRETORY SYSTEMS; TIME FACTORS;

EID: 2442546690     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4938-03.2004     Document Type: Article

References (29)

1. Baker JD, McNabb SL, Truman JW (1999) The hormonal coordination of behavior and physiology at adult ecdysis in Drosophila melanogaster. J Exp Biol 202:3037-3048.
2. Edelman GM, Gally JA (2001) Degeneracy and complexity in biological systems. Proc Natl Acad Sci USA 98:13763-13768.
3. Eldridge R, Horodyski FM, Morton DB, O'Reilly DR, Truman JW, Riddiford LM, Miller LK (1991) Expression of an eclosion hormone gene in insect cells using baculovirus vectors. Insect Biochem 21:341-351.
4. Ewer J, Reynolds S (2002) Neuropeptide control of molting in insects. In: Hormones, brain and behavior (Pfaff DW, Arnold AP, Fahrbach SE, Etgen AM, Rubin RT, eds), pp 1-92. San Diego: Academic.
5. Ewer J, Truman JW (1996) Increases in cyclic 3′,5′-guanosine monophosphate (cGMP) occur at ecdysis in an evolutionarily conserved crustacean cardioactive peptide-immunoreactive insect neuronal network. J Comp Neurol 370:330-341.
6. Ewer J, Gammie SC, Truman JW (1997) Control of insect ecdysis by a positive-feedback endocrine system: roles of eclosion hormone and ecdysis triggering hormone. J Exp Biol 200:869-881.
7. Gammie SC, Truman JW (1997) Neuropeptide hierarchies and the activation of sequential motor behaviors in the hawkmoth, Manduca sexta. J Neurosci 17:4389-4397.
8. Greenspan RJ (2001) The flexible genome. Nat Rev Genet 2:383-387.
9. Horodyski FM, Ewer J, Riddiford LM, Truman JW (1993) Isolation, characterization and expression of the eclosion hormone gene of Drosophila melanogaster. Eur J Biochem 215:221-228.
10. Husain QM, Ewer J (2004) Use of targetable gfp-tagged neuropeptide for visualizing neuropeptide release following execution of a behavior. J Neurobiol 59:181-191.
11. Kingan TG, Adams ME (2000) Ecdysteroids regulate secretory competence in inka cells. J Exp Biol 203:3011-3018.
12. Kingan TG, Gray W, Zitnan D, Adams ME (1997) Regulation of ecdysis-triggering hormone release by eclosion hormone. J Exp Biol 200:3245-3256.
13. Kingan TG, Cardullo RA, Adams ME (2001) Signal transduction in eclosion hormone-induced secretion of ecdysis-triggering hormone. J Biol Chem 276:25136-25142.
14. McNabb SL, Baker JD, Agapite J, Steller H, Riddiford LM, Truman JW (1997) Disruption of behavioral sequence by targeted death of peptidergic neurons in Drosophila. Neuron 19:813-823.
15. Meng X, Wahlstrom G, Immonen T, Kolmer M, Tirronen M, Predel R, Kalkkinen N, Heino T, Sariola H, Roos C (2002) The Drosophila hugin gene codes for myostimulatory and ecdysis-modifying neuropeptides. Mech Dev 117:5-13.
16. Miller MW, AA, Cropper EC, Vilim FS, Karagogeos D, Kupfermann I, Weiss KR (1991) Localization of myomodulin-like immunoreactivity in the central nervous system and peripheral tissues of Aplysia californica. J Comp Neurol 314:627-644.
17. Nässel DR (2000) Functional roles of neuropeptides in the insect central nervous system. Naturwissenschaften 87:439-449.
18. Nässel DR (2002) Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones. Prog Neurobiol 68:1-84.
19. O'Brien MA, Taghert PH (1998) A peritracheal neuropeptide system in insects: release of myomodulin-like peptides at ecdysis. J Exp Biol 201:193-209.
20. Park J, Schroeder AJ, Helfrich-Förster C, Jackson FR, Ewer J (2003) Targeted ablation of CCAP neuropeptide-containing neurons of Drosophila causes specific defects in execution and circadian timing of behavior. Development 130:2645-2656.
21. Park Y, Zitnan D, Gill SS, Adams ME (1999) Molecular cloning and biological activity of ecdysis-triggering hormones in Drosophila melanogaster. FEBS Lett 463:133-138.
22. Park Y, Filippov V, Gill SS, Adams ME (2002) Deletion of the ecdysis-triggering hormone gene leads to a lethal ecdysis deficiency. Development 129:493-503.
23. Predel R, Eckert M (2000) Neurosecretion: peptidergic systems in insects. Naturwissenschaften 87:343-350.
24. Strand FL (1999) Neuropeptides: regulators of physiological processes. Cambridge, MA: MIT.
25. Truman JW, Mumby SM, Welch SK (1979) Involvement of cyclic GMP in the release of stereotyped behavior patterns in moths by a peptide hormone. J Exp Biol 84:201-212.
26. Zitnan D, Kingan TG, Hermesman JL, Adams ME (1996) Identification of ecdysis-triggering hormone from epitracheal endocrine system. Science 271:88-91.
27. Zitnan D, Ross LS, Zitnanova I, Hermesman JL, Gill SS, Adams ME (1999) Steroid induction of a peptide hormone gene leads to orchestration of a defined behavioral sequence. Neuron 23:523-535.
28. Zitnan D, Hollar L, Spalovska II, Takac P, Zitnanova II, Gill SS, Adams ME (2002) Molecular cloning and function of ecdysis-triggering hormones in the silkworm Bombyx mori. J Exp Biol 205:3459-3473.
29. Zitnan D, Zitnanova I, Spalovska II, Takac P, Park Y, Adams ME (2003) Conservation of ecdysis-triggering hormone signaling in insects. J Exp Biol 206:1275-1289.