Hepatoprotective Effect of Sabina przewalskii against Menadione-induced Toxicity

Phytotherapy Research

Volumn 18, Issue 4, 2004, Pages 329-331

  Ip, Siu Po ^a   Woo, Ka Yan ^a   Lau, Oi Wah ^a   Che, Chun Tao ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Free radical scavenger; Hepatotoxicity; Lipid peroxidation; Menadione; Sabina przewalskii

Indexed keywords

ACETIC ACID ETHYL ESTER; ALANINE AMINOTRANSFERASE; ALCOHOL; CHLOROFORM; GLUTATHIONE; HEXANE; HYDROPEROXIDE; LIVER PROTECTIVE AGENT; LUCIGENIN; MENADIONE; METHANOL; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SABINA PRZEWALSKII EXTRACT; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG ISOLATION; FEMALE; IN VITRO STUDY; LIPID PEROXIDATION; LIVER CELL; LIVER PROTECTION; LIVER TOXICITY; MEDICINAL PLANT; MOUSE; NONHUMAN; SABINA PRZEWALSKII; THIN LAYER CHROMATOGRAPHY;

ALANINE TRANSAMINASE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATITIS, TOXIC; HEPATOCYTES; JUNIPERUS; LIPID PEROXIDATION; MICE; MICE, INBRED BALB C; NAD; PHYTOTHERAPY; PLANT EXTRACTS; PROTECTIVE AGENTS; VITAMIN K 3;

SABINA; SABINA PRZEWALSKII;

EID: 2442546509     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1326     Document Type: Article

References (16)

1. Adams RP. 2000. Systematics of the one seeded Juniperus of the eastern hemisphere based on leaf essential oils and random amplified polymorphic DNAs (RAPDs). Biochem Syst Ecol 28: 529-543.
2. Aherne SA, O'Brien NM. 2000. Mechanism of protection by the flavonoids, quercetin and rutin, against tert-butylhydroperoxide- and menadione-induced DNA single strand breaks in Caco-2 cells. Free Rad Biol Med 29: 507-514.
3. Chen Y, Chan PH, Swanson RA. 2001. Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury. GLIA 33: 343-347.
4. Chiou TJ, Chou YT, Tzeng WF. 1998. Menadione-induced cell degeneration is related to lipid peroxidation in human cancer cells. Proc Natl Sci Council Republic China B 22: 13-21.
5. Guzik TJ, West NE, Black E, et al. 2000. Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors. Circ Res 86: E85-E90.
6. Ip SP, Ko KM. 1996. The crucial antioxidant action of schisandrin B in protecting against carbon tetrachloride hepatotoxicity in mice: a comparative study with butylated hydroxytoluene. Biochem Pharmacol 52: 1687-1693.
7. Ip SP, Yiu HY, Ko KM. 2000. Schisandrin B protects against menadione-induced hepatotoxicity by enhancing DT-diaphorase activity. Mol Cell Biochem 208: 151-155.
8. Kappus H. 1986. Overview of enzyme systems involved in bioreduction of drugs and in redox cycling. Biochem Pharmacol 35: 1-6.
9. Ko KM, Yick PK, Poon MK, Ip SP. 1994. Prooxidant and antioxidant effects of Trolox on ferric ion-induced oxidation of erythrocyte membrane lipids. Mol Cell Biochem 141: 65-70.
10. Luo DS. 1997. Zhong Hua Zang Ben Cao (Chinese Tibetan Medicines), 1st edn. Minzu Chubanshe: Beijing.
11. Margolin KA, Akman SA, Leong LA, et al. 1995. Phase I study of mitomycin C and menadione in advanced solid tumors. Cancer Chemother Pharmacol 36: 293-298.
12. Tzeng WF, Lee JL, Chiou TJ. 1995. The role of lipid peroxidation in menadione-mediated toxicity in cardiomyocytes. J Mol Cell Cardiol 27: 1999-2008.
13. Zong YY, Che CT. 1995. Glucosides from Lagotis brevituba. Planta Med 61: 585-586.
14. Zong YY, Lowell K, Jiang P, Che CT, Pezzuto JM, Fong HHS. 1991. Phenolic constituents of Rhodiola coccinea, a Tibetan folk medicine. Planta Med 57: 589.
15. Zong YY, Yu MT, Huang LC, Chang YP, Che CT. 1994. Studies of Tibetan medicinal plants. II. Antitumor activity of Saussurea eopygmaea. Int J Pharmacogn 32: 284-293.
16. Zong YY, Dang HQ, Luo GF, Zhang XF, Che CT. 2000. Antitumor screening research from 110 Tibetan medicines. J Pharm Practice (China) 18: 290-291.