Comparative investigation of the desensitizing efficacy of a new dentifrice containing 5.5% potassium citrate: An eight-week clinical study

Journal of Clinical Dentistry

Volumn 15, Issue 1, 2004, Pages 6-10

  Hu, Deyu ^a   Zhang, Yun Po ^b   Chaknis, Patricia ^b   Petrone, Margaret E ^b   Volpe, Anthony R ^b   DeVizio, William ^b  

^a SICHUAN UNIVERSITY   (China)

^b Global Personal Care and Skin Health R D   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE POTASSIUM; FLUORIDE SODIUM; FLUOROPHOSPHATE; POTASSIUM CHLORIDE; SILICON DIOXIDE; TOOTHPASTE; TRICLOSAN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENTIN; DESENSITIZATION; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; THERMOSTABILITY; TOOTH BRUSHING; TOUCH;

DENTIFRICES; DENTIN SENSITIVITY; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; FEMALE; FLUORIDES; HUMANS; MALE; MIDDLE AGED; NITRATES; PHOSPHATES; POTASSIUM CITRATE; SILICON DIOXIDE;

EID: 2442544710     PISSN: 08958831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Gysi A: An attempt to explain the sensitiveness of dentine. Br J Dent Res 43:865, 1900.
2. Brannstrom M: Dentin sensitivity and aspiration of odontoblasts. JADA 66:366-370, 1963.
3. Pashley DH: Mechanisms of dentin sensitivity. Dent Clin North Am 34: 449-473, 1990.
4. Narhi M, Yamamoto H, Ngassapa D, Hirvohen T: The neurophysiological basis and the role of inflammatory reactions in dentine hypersensitivity. Arch Oral Biol 39:23S-30S, 1994.
5. Matthews B, Andrew D, Amess TR, Ikeda H, Vongsavan N: The functional properties of intradental nerves. In: Proceedings of the International Conference on Dentin/Pulp Complex, Shimono M, Maeda T, Suda H, Takahashi K, eds., Quintessence Pub. Co. Ltd, Tokyo, pp. 146-153, 1996.
6. Orachardson R, Gillam DG: The efficacy of potassium salts as agents for treating dentin hypersensitivity. J Orofac Pain 14:9-19, 2000.
7. Hodosh M: A superior desensitizer - Potassium nitrate. JADA 88:831-832, 1974.
8. Kim S: Hypersensitive teeth; Desensitization of pulpal sensory nerves. J Endod 12:482-485, 1986.
9. Tarbet WJ, Silverman G, Stolman JM, Fratarcangelo PA: Clinical evaluation of a new treatment for dentinal hypersensitivity. J Periodontol 51:535-540, 1980.
10. Tarbet WJ, Silverman G, Fratarcangelo PA, Kanapka JA: Home treatment for dentinal hypersensitivity: A comparative study. JADA 105:227-230, 1982.
11. Silverman G: The sensitivity-reducing effect of brushing with a potassium nitrate-sodium monofluorophosphate dentifrice. Compend Cont Educ Dent 6:131-133, 136, 1985.
12. Gillam DG: Clinical trial designs for testing of products for dentine hypersensitivity - A review. Periodont Abstr. 45:37-46, 1997.
13. Chesters R, Kaufman HW, Wolff MS, Huntington E, Kleinberg I: Use of multiple sensitivity measurements and logit statistical analysis to assess the effectiveness of a potassium citrate-containing dentifrice in reducing dentinal hypersensitivity. J Clin Periodontol 19:256-261, 1992.
14. Clark GE, Troullos ES: Designing hypersensitivity clinical studies. Dent Clin North Am 34:531-544, 1990.
15. Gillam DG, Bulman JS, Jackson RJ, Newman HN: Efficacy of a potassium nitrate mouthwash in alleviating cervical dentine sensitivity (CDS). J Clin Periodontol 23:993-997, 1996.
16. Schiff T, Dotson M, Cohen S, DeVizio W, McCool J, Volpe A: Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM/MA copolymer, and sodium fluoride on dentifrice hypersensitivity: A twelve-week clinical study. J Clin Dent 5 (Spec Iss):87-92, 1994.
17. Greenhill JD, Pashley DH: The effects of desensitizing agents on the hydraulic conductance of human dentin in vitro. J Dent Res 60:686-698, 1981.
18. Peacock JM, Orchardson R: Action potential conduction block of nerves in vitro by potassium citrate, potassium tartrate and potassium oxalate. J Clin Periodontol 26:33-37, 1999.