Trypanocidal Activity of Chemical Constituents from Lychnophora salicifolia Mart

Phytotherapy Research

Volumn 18, Issue 4, 2004, Pages 332-334

  Jordão, Christiane Oliveira ^a   Vichnewski, Walter ^a   Petto De Souza, Glória Emília ^a   Albuquerque, Sérgio ^a   Callegari Lopes, João Luis ^a,b  

^a Faculdade Cie Farmaceuticas R   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Flavonoids; Lychnophora salicifolia; Sesquiterpenoids; Trypanocidal activity; Writhing test

Indexed keywords

3,5 DIHYDROXY 3',4',7 TRIMETHOXYFLAVONE; ACETIC ACID; ACETIC ACID ETHYL ESTER; ANTINOCICEPTIVE AGENT; ANTITRYPANOSOMAL AGENT; CRYSTAL VIOLET; FLAVONOID; LYCHNOPHOLIC ACID; LYCHNOPHORA SALICIFOLIA EXTRACT; PLANT EXTRACT; SESQUITERPENOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; ASTERACEAE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; CHAGAS DISEASE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; INFLORESCENCE; LYCHNOPHORA SALICIFOLIA; MALE; MOUSE; NONHUMAN; PLANT LEAF; PROTON NUCLEAR MAGNETIC RESONANCE; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE; WRITHING TEST;

ANIMALS; ASTERACEAE; CHAGAS DISEASE; PARASITIC SENSITIVITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

LYCHNOPHORA;

EID: 2442535954     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1366     Document Type: Article

References (13)

1. Brener Z. 1962. Therapeutic activity and criterion of cure on mice experimentally infected with Trypanosoma cruzi. Rev Inst Med Trop São Paulo 4: 389-396.
2. Cerqueira MBS, Souza JT, Amado Júnior R, Peixoto ABF. 1987. Ação analgésica do extrato bruto aquoso do caule e das folhas de Lychnophora ericoides Mart. (arnica). Cienc e Cult 39: 551-553.
3. Chiari E, Duarte DS, Raslan DA, et al. 1996. In vitro screening of Asteraceae plant species against T. cruzi. Phytother Res 10: 636-638.
4. Hamilton MA, Russo RC, Thurston RV. 1978. Trimmed Spearman-Karber method for estimating median lethal concentrations in toxicity bioassays. Environ Sci Technol 12: 417.
5. Koster R, Anderson M, Beer EJ. 1959. Acetic acid for analgesic screening. Fed Proc 18: 412.
6. Le Quesne PW, Menachery MD, Raffauf RF. 1979 Antitumor plants. Part IX. Structural reassigments for three flavonoids from Lychnophora affinis Gardn. J Nat Prod 42: 320-321.
7. Le Quesne PW, Menachery MD, Pastore MP, et al. 1982. Antitumor plants 12. Further sesquiterpenoid constituents of Lychnophora affinis Gardn. (Compositae). X-ray structure analysis of Lychnophorolide A. J Org Chem 47: 1519-1521.
8. Nussenweig V, Sonntag R, Biancalana A, et al. 1953. Ação de corantes tri-fenil-metânicos sobre Trypanosoma cruzi in vitro. Emprego de violeta genciana na profilaxia da transmissão da moléstia de Chagas' por transfusao de sangue. O Hospital 44: 731-744.
9. Ribeiro A, Piló-Veloso D, Romanha AJ, Zani CL. 1997. Trypanocidal flavonoids from Trixis vauthieri. J Nat Prod 60: 836-838.
10. Robinson H. 1999. Generic and subtribal classification of American Vernonieae. Smithsonian Contributions to Botany 89: 116.
11. Rojas de Arias A, Ferro E, Inchausti A, et al. 1995. Mutagenecity, insecticidal and trypanocidal activity of some Paraguayan Asteraceae. J Ethnopharmacol 45: 35-41.
12. Souza HM. 1989. Quimioprofilaxia da Doença de Chagas' transfusional. Rev Soc Bras Med Trop 22: 1-3.
13. Valesi AG, Rodriguez E, Velde GV, Mabry TJ. 1972. Methylated flavonols in Larrea cuneifolia. Phytochemistry 11: 2821-2826.