Is haloperidol or a benzodiazepine the safest treatment for acute psychosis in the critically ill patient?

Interactive Cardiovascular and Thoracic Surgery

Volumn 3, Issue 2, 2004, Pages 233-236

  Khasati, Noman ^a   Thompson, Jacqueline ^b   Dunning, Joel ^b  

^a WYTHENSHAWE HOSPITAL   (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Diazepam; Evidence based medicine; Haloperidol; Lorazepam; Thoracic surgery

Indexed keywords

BENZODIAZEPINE; CHLORPROMAZINE; DIAZEPAM; HALOPERIDOL; LORAZEPAM;

ACUTE PSYCHOSIS; AGITATION; ARTICLE; ATAXIA; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONFUSION; CRITICAL ILLNESS; DOSE RESPONSE; DRUG EFFECT; DRUG SAFETY; EXTRAPYRAMIDAL SYNDROME; HEART SURGERY; HUMAN; HYPOTENSION; MEDICAL LITERATURE; MENTAL PATIENT; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PSYCHIATRIC TREATMENT; QUESTIONNAIRE; SEDATION; SIDE EFFECT; TORSADE DES POINTES;

EID: 2442532675     PISSN: 15699293     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.icvts.2003.11.005     Document Type: Article

References (10)

1. Dunning J., Prendergast B., Mackway-Jones K. Towards evidence-based medicine in cardiothoracic surgery: best BETS. Interac Cardiovasc Thorac Surg. 2:2003;405-409
2. Hassaballa H.A., Balk R.A. Torsade de pointes associated with the administration of intravenous haloperidol [Review] [29 refs]. Am J Ther. 10:2003;58-60
3. Tisdale J.E., Rasty S., Padhi I.D., Sharma N.D., Rosman H. The effect of intravenous haloperidol on QT interval dispersion in critically ill patients: comparison with QT interval prolongation for assessment of risk of Torsades de Pointes [erratum appears in J Clin Pharmacol 42(5):577-9]. J Clin Pharmacol. 41:2002;1310-1318
4. Breitbart W., Platt M.M., Deverenco M., Grau C., Corbera K., Raymond S., Lund S., Jacobson P. A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. Am J Psychiat. 153:1996;231-237
5. Shapiro B.A., Warren J., Egol A.B., Greenbaum D.M., Jacobi J., Nasraway S.A., Schein R.M., Spevetz A., Stone J.R. Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. Soc Crit Care Med [comment]. Crit Care Med. 23:1995;1596-1600
6. Huyse F., van Schijndel R.S. Haloperidol and cardiac arrest. Lancet. 2:1988;568-569
7. Tesar G.E., Stern T.A. Rapid tranquilization of the agitated intensive care unit patient. J Intensive Care Med. 3:1988;195-201
8. Adams F. Emergency intravenous sedation of the delirious, medically ill patient. J Clin Psychiat. 49:(Suppl 7):1988
9. Tesar G.E., Murray G.B., Cassem N.H. Use of high-dose intravenous haloperidol in the treatment of agitated cardiac patients. J Clin Psychopharmacol. 5:1985;344-347
10. Rao S., Sherbaniuk R.W., Prasad K., Lee S.J., Sproule B.J. Cardiopulmonary effects of diazepam. Clin Pharmacol Ther. 14:1973;182-189