Synthesis of fluorescent derivatization reagents: Reaction of isatin with 3-aryl-7-diethylamino-coumarins and their fluorescent properties

Heterocycles

Volumn 63, Issue 5, 2004, Pages 1083-1091

  Nishizono, Naozumi ^a   Oda, Kazuaki ^a   Kato, Yutaka ^a   Ohno, Kosei ^a   Minami, Masaru ^a   Machida, Minoru ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 DIETHYLAMINOCOUMARIN DERIVATIVE; COUMARIN DERIVATIVE; FLUORESCENT DYE; ISATIN; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; FLUORESCENCE; SYNTHESIS;

EID: 2442511023     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-04-10021     Document Type: Article

References (10)

1. Fluorescent Labeling Reagents. Part 6. Part 5. N. Nishizono, K. Oda, K. Ohno, M. Minami, and M. Machida, Heterocycles, 2001, 55, 1897.
2. a) N. Hamaue, M. Minami, M. Hirafuji, M. Terado, M. Machida, N. Yamazaki, M. Yoshioka, A. Ogata, and K. Tashiro, CNS Drug Reviews, 1999, 5, 331.;
3. N. Hamaue, M. Minami, M. Terado, M. Hirafuji, T. Endo, M. Machida, T. Hiroshige, A. Ogata, K. Tashiro, H. Saito, and S. H. Parvez, Neurotoxicology, 2004, 25, 205.
4. K. Niume, S. Kurosawa, F. Toda, M. Hasegawa, and Y. Iwakura, Bull. Chem. Soc. Jpn., 1982, 55, 2293.
5. E. M. Beccalli and A. Marchesini, Tetrahedron, 1993, 49, 4741.
6. H. N. Song, H. J. Lee, H. R. Kim, E. K. Ryu, and J. N. Kim, Syn. Commun., 1999, 29, 3303.
7. P. Hewawasam and M. Erway, Tetrahedron Lett., 1998, 39, 3981.
8. F. H. Osman and F. A. El-Samahy, Tetrahedron, 2000, 56, 1863.
9. The compound (8b) as an internal standard for HPLC was prepared by the coupling of 2c with N-methylisatin.
10. H. Takechi, Y. Oda, N. Nishizono, K. Oda, and M. Machida, Chem. Pharm. Bull., 2000, 48, 1702.