Effect of Low-Dose Ketamine on Redistribution Hypothermia during Spinal Anesthesia Sedated by Propofol

Journal of Nippon Medical School

Volumn 71, Issue 2, 2004, Pages 92-98

  Kinoshita, Takao ^a,b   Suzuki, Manzo ^a   Shimada, Yoichi ^a   Ogawa, Ryo ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b NIPPON MEDICAL SCHOOL MUSASHI KOSUGI HOSPITAL   (Japan)

Author keywords

Hypothermia; Ketamine; Spinal anesthesia

Indexed keywords

ATROPINE; BUPIVACAINE; EPHEDRINE; HYDROXYZINE; KETAMINE; PENTAZOCINE; PLACEBO; PROPOFOL;

ADULT; AGED; ANESTHESIOLOGICAL TECHNIQUES; ARTICLE; BODY TEMPERATURE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORE TEMPERATURE; DOSE RESPONSE; DRUG EFFECT; DRUG INFUSION; FEMALE; HUMAN; HYPOTHERMIA; MALE; RANDOMIZED CONTROLLED TRIAL; SEDATION; SPINAL ANESTHESIA;

ADULT; AGED; ANESTHESIA, SPINAL; ANTI-INFECTIVE AGENTS; BODY TEMPERATURE; FEMALE; HUMANS; HYPOTHERMIA; KETAMINE; MALE; MIDDLE AGED; PROPOFOL;

EID: 2442489897     PISSN: 13454676     EISSN: None     Source Type: Journal    
DOI: 10.1272/jnms.71.92     Document Type: Article

References (17)

1. Emerick TH, Ozaki M, Sessler DI, Walters K, Schroeder M: Epidural anesthesia increases apparent leg temperature and decreases the shivering threshold. Anesthesiology 1994; 81: 289-298.
2. Arkilic CF, Akca O, Taguchi A, Sessler DI, Kurz A: Temperature monitoring and management during neuraxial anesthesia: an observational study. Anesth Analg 2000; 91: 662-666.
3. Matsukawa T, Kurz A, Sessler DI, Bjoksten AR, Merrifield B, Cheng C: Propofol linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology 1995; 82: 1169-1180.
4. Ikeda T, Kazama T, Sessler DI, Toriyama S, Niwa K, Shimada C, Sato S: Induction of anesthesia with ketamine reduces the magnitude of redistribution hypothermia. Anesth Analg 2001; 93: 934-938.
5. Bowdle TA, Radant AD, Cowley DS, Kharasch ED, Strassman RJ, Roy-Byrne PP: Psychedelic effects of ketamine in healthy volunteers. Relationship to steady-state plasma concentrations. Anesthesiology 1998; 88: 82-88.
6. Chernik DA, Gillings D, Laine H, Hendler J, Silver JM, Davidson AB, Schwam EM, Siegel JL: Validity and reliability of the observer's assessment of alertness/sedation scale: study with intravenous midazolam. J Clin Psycopharmacol 1990; 10: 244-251.
7. Kurz A, Go JC, Sessler DI, Kaser K, Larson MD, Bjorksten AR: Alfentanil slightly increases the sweating thresholds and markedly reduces the vasoconstriction and shivering thresholds. Anesthesiology 1995; 83: 293-299.
8. Kurz A, Sessler DI, Shroeder M, Kurz M: Thermoregulatory response thresholds during spinal anesthesia. Anesth Analg 1993; 77: 721-726.
9. Robinson BJ, Ebert TJ, O'Brien TJ, Collinco MD, Muzi M: Mechanism whereby propofol mediates peripheral vasodilation in humans: Sympathoinhibition or direct vascular relaxation. Anesthesiology 1997; 82: 64-72.
10. Leslie K, Sessler DI, Bjorksten AR, Ozaki M, Matsukawa T, Schroder M: Propofol causes a dose-dependent decrease in the thermoregulatory threshold for vasoconstriction but has little effect on sweating. Anesthesiology 1994; 81: 353-360.
11. Bentley GN, Goodchild CS: Vascular effect of propofol: smooth muscle relaxation in isolated veins and arteries. J Pharm Pharmacol 1989; 41: 797-798.
12. Ikeda T, Ozaki M, Sessler DI, Kazama T, Ikeda K, Sato S: Intra operative phenylephrine infusion decreases the magnitude of redistribution hypothermia. Anesth Analg 1999; 89: 462-465.
13. Kienbaum P, Heuter T, Michel MC, Peters J: Racemic ketamine decreases muscle sympathetic activity nut maintains the neural response to hypotensive challenges in humans. Anesthesiology 2000; 92: 94-101.
14. Lundy PM, Lockwood PA, Thompson G, Frew R: Differential effects of ketamine isomers on neural and extraneural cathecolamine uptake mechanisms. Anesthesiology 1986; 64: 359-363.
15. Kitagawa H, Yamazaki T, Akiyama T, Mori H, Sunagawa K: Effects of ketamine on exocytotic and non-exocytotic noradrenaline release. Neurochemistry International 2003; 42: 261-267.
16. Hemmingsen G, Nielsen JFK: Intravenous ketamine for prevention of severe hypotension during spinal anesthesia Acta Anaesthesiol Scand 1991; 35: 755-757.
17. Frizelle HP, Duranteau J, Samji K: A comparison of propofol with propofol-ketamine combination for sedation during spinal anesthesia. Anesth Analg 1997; 84: 1318-1322.