Regulation of enzymes involved in methionine biosynthesis in Corynebacterium glutamicum

Journal of Microbiology and Biotechnology

Volumn 14, Issue 2, 2004, Pages 373-378

  Yeom, Hye Jin ^a   Hwang, Byung Joon ^a   Lee, Myong Sok ^b   Kim, Younhee ^c   Lee, Heung Shick ^a  

^a Korea University   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Semyung University   (South Korea)

Author keywords

synthase; Corynebacterium glutamicum; Cystathionine; Cystathionine lyase; Homoserine acetyltransferase; Methionine

Indexed keywords

CYSTATHIONINE BETA SYNTHASE; CYSTEINE; HOMOSERINE ACETYLTRANSFERASE; ISOLEUCINE; LYSINE; METHIONINE; S ADENOSYLMETHIONINE; THREONINE;

ARTICLE; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME REPRESSION; ENZYME SYNTHESIS; GENE CONTROL; GENE EXPRESSION; GENETIC CODE; NONHUMAN;

CORYNEBACTERIUM; CORYNEBACTERIUM GLUTAMICUM;

EID: 2442466798     PISSN: 10177825     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Bradford, M. M. 1976. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
2. Bright, S. W. J., P. J. Lea, and B. J. Miflin. 1979. The regulation of methionine biosynthesis and metabolism in plants and bacteria. Ciba Found. Symp. 72: 101-117.
3. de Graaf, A. A., L. Eggeling, and H. Sahm. 2001. Metabolic engineering for L-lysine production by Corynebacterium glutamicum. Adv. Biochem. Eng. Biotechnol. 73: 9-29.
4. Foglino, M., F. Borne, M. Bally, G. Ball, and J. C. Patte. 1995. A direct sulfhydrylation pathway is used for methionine biosynthesis in Pseudomonas aeruginosa. Microbiology 141: 431-439.
5. Follettie, M. T., O. P. Peoples, C. Agoropoulou, and A. J. Sinskey. 1993. Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon. J. Bacteriol. 175: 4096-4103.
6. Follettie, M. T. and A. J. Sinskey. 1986. Recombinant DNA technology for Corynebacterium glutamicum. Food Technol. 40: 88-94.
7. Giovanelli, J., S. H. Mudd, and A. H. Datko. 1978. Homocysteine biosynthesis in green plants. Physiological importance of the transsulfuration pathway in Chlorella sorokiniana growing under steady state conditions with limiting sulfate. J. Biol. Chem. 253: 5665-5677.
8. Herrman, T. 2003. Industrial production of amino acids by coryneform bacteria. J. Biotechnol. 104: 155-172.
9. Hwang, B.-J., Y. Kim, H.-B. Kim, H.J. Hwang, J.-H. Kim, and H.-S. Lee. 1999. Analysis of Corynebacterium glutamicum methionine biosynthetic pathway: Isolation and analysis of metB encoding cystathionine γ-synthase. Mol. Cells 9: 300-308.
10. Hwang B.-J., H.-J. Yeom, Y. Kim, and H.-S. Lee 2002. Corynebacterium glutamicum utilizes both transsulfuration and direct sulthydrylation pathways for methionine biosynthesis. J. Bacteriol. 184: 1277-1286.
11. Jetten, M. S. M. and A. J. Sinskey. 1993. Characterization of phosphoenolpyruvate carboxykinase from Corynebacterium glutamicum. FEMS Microbiol. Lett. 111: 183-188.
12. Jetten, M. S. and A. J. Sinskey. 1995. Recent advances in the physiology and genetics of amino acid-producing bacteria. Crit. Rev. Biotechnol. 15: 73-103.
13. Kase, H. and K. Nakayama. 1974. Production of O-acetyl-L-homoserine by methionine analog-resistant mutants and regulation of homoserine-O-transacetylase in Corynebacterium glutamicum. Agric. Biol. Chem. 38: 2021-2030.
14. Kase, H. and K. Nakayama. 1974b. The regulation of L-methionine synthesis and the properties of cystathionine γ -synthase and β-cystathionase in Corynebacterium glutamicum. Agric. Biol. Chem. 38: 2235-2242.
15. Kase, H. and K. Nakayama. 1975. Isolation and characterization of S-adenosylmethionine-requiring mutants and role of S-adenosylmethionine in the regulation of methionine biosynthesis in Corynebacterium glutamicum. Agric. Biol. Chem. 39: 161-168.
16. Kim, H.-J., J.-S. Park, H.-S. Lee, and Y. Kim. 2002. Utilization of lacZ to isolate regulatory genes from Corynebacterium glutamicum. J. Microbiol. Biotechnol. 12: 336-339.
17. Kim, J.-W, H.-J. Kim, Y. Kim, M.-S. Lee, and H.-S. Lee. 2001. Properties of the Corynebacterium glutamicum metC gene encoding cystathionine β-lyase. Mol. Cells 11: 220-225.
18. Lee, J., A. Goel, M. M. Ataai, and M. M. Domach. 2002. Flux regulation patterns and energy audit of E. coli B/r and K-12. J. Microbiol. Biotechnol. 12: 258-267.
19. Nagai, S. and M. Flavin. 1971. Synthesis of O-acetylhomoserine. Methods Enzymol. 17B: 423-424.
20. Ozaki, H. and I. Shiio. 1982. Methionine biosynthesis in Brevibacterium flavum: Properties and essential role of O-acetylhomoserine sulfhydrylase. J. Biochem. 91: 1163-1171.
21. Park, S.-D., J.-Y. Lee, Y. Kim, J.-H. Kim, and H.-S. Lee. 1998. Isolation and analysis of metA, a methionine biosynthetic gene encoding homoserine acetyltransferase in Corynebacterium glutamicum. Mol. Cells 8: 286-294.
22. Paszewski, A., W. Prazmo, J. Nadolska, and M. Regulski. 1984. Mutations affecting the sulphur assimilation pathway in Aspergillus nidulans: Their effect on sulphur amino acid metabolism. J. Gen. Microbiol. 130: 1113-1121.
23. Ravanel, S., M. Droux, and R. Douce. 1995. Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine γ-synthase from spinach chloroplasts. Arch. Biochem. Biophys. 316: 572-584.
24. Rey D. A., A. Pühler, and J. Kalinowski. 2003. The putative transcriptional repressor McbR, member of the TetR-family, is involved in the regulation of the metabolic metwork directing the synthesis of sulfur containing amino acids in Corynebacterium glutamicum. J. Biotechnol. 103: 51-65.
25. Rossol, I. and A. Pühler. 1992. The Corynebacterium glutamicum aecD gene encodes a C-S lyase with α,β-elimination activity that degrades aminoethylcysteine. J. Bacteriol. 174: 2968-2977.
26. Rückert, C., A. Pühler, and J. Kalinowski. 2003. Genomewide analysis of the L-methionine biosynthetic pathway in Corynebacterium glutamicum by targeted gene deletion and homologous complementation. J. Biotechnol. 104: 213-228.
27. Sahm, H., L. Eggeling, and A. A. de Graaf. 2000. Pathway analysis and metabolic engineering in Corynebacterium glutamicum. Biol. Chem. 381: 899-910.
28. Sahm, H., L. Eggeling, B. Eikmanns, and R. Krämer. 1995. Metabolic design in amino acid producing bacterium Corynebacterium glutamicum. FEMS Microbiol. Rev. 16: 243-252.
29. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, U.S.A.
30. Schrumpf, B., A. Schwarzer, J. Kalinowski, A. Pühler, L. Eggeling, and H. Sahm. 1991. A functionally split pathway for lysine synthesis in Corynebacterium glutamicum. J. Bacteriol. 173: 4510-4516.
31. Vermeij, P. and M. A. Kertesz. 1999. Pathways of assimilative sulfur metabolism in Pseudomonas putida. J. Bacteriol. 181: 5833-5837.
32. von der Osten, C. H., C. Gioannetti, and A. J. Sinskey. 1989. Design of a defined medium for growth of Corynebacterium glutamicum in which citrate facilitates iron uptake. Biotechnol. Lett. 11: 11-16.
33. Wada, M., N. Awano, K. Haisa, H. Takagi, and S. Nakamori. 2002. Purification, characterization and identification of cysteine desulfhydrase of Corynebacterium glutamicum, and its relationship to cysteine production. FEMS Microbiol. Lett. 217: 103-107.
34. Wiebers, J. L. and H. R. Garner. 1967. Homocysteine and cysteine synthetases of Neurospora crassa. Purification, properties, and feedback control of activity. J. Biol. Chem. 242: 12-23.
35. Yamagata, S. 1989. Roles of O-acetyl-L-homoserine sulfhydrylases in microorganisms. Biochimie 71: 1125-1143.