Differential diagnosis and management of neonatal hypoglycemia

Pediatric Clinics of North America

Volumn 51, Issue 3, 2004, Pages 703-723

  Sperling, Mark A ^a,b,e   Menon, Ram K ^c,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOLAMINE; FATTY ACID; FRUCTOSE; GALACTOSE; GLUCOSE; GLYCEROL; GLYCOGEN; MANNOSE PHOSPHATE ISOMERASE; PROTEIN DERIVATIVE; TRIACYLGLYCEROL;

ANXIETY; APNEA; AUTOSOMAL DOMINANT DISORDER; CATECHOLAMINE SYNTHESIS; CLINICAL FEATURE; COMA; CONVULSION; CORRELATION ANALYSIS; CYANOSIS; DEVELOPMENTAL DISORDER; DIET RESTRICTION; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; FEEDING DISORDER; FOOD DEPRIVATION; GALACTOSEMIA; GENE MUTATION; GESTATION PERIOD; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; GLYCOGEN METABOLISM; GLYCOLYSIS; HEART PALPITATION; HEMOCONCENTRATION; HEREDITARY FRUCTOSE INTOLERANCE; HUMAN; HYPOGLYCEMIA; HYPOPITUITARISM; INFANCY; INFANT; INTRAARTERIAL DRUG ADMINISTRATION; KETOGENESIS; LOW BIRTH WEIGHT; METABOLIC ACIDOSIS; MOLECULAR MECHANICS; MORBIDITY; MYOCLONUS SEIZURE; NEWBORN; OXIDATION; PATHOGENESIS; RESPIRATORY DISTRESS; REVIEW; SEPSIS; SOMNOLENCE; STATISTICAL SIGNIFICANCE; SWEATING; TACHYCARDIA; WILTING;

DIAGNOSIS, DIFFERENTIAL; HUMANS; HYPOGLYCEMIA; INFANT, NEWBORN; METABOLISM, INBORN ERRORS;

EID: 2442442843     PISSN: 00313955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pcl.2004.01.014     Document Type: Review

References (49)

1. Menon R.K., Sperling M.A. Carbohydrate metabolism in neonatal adaptation: the transition to post-natal life. Semin Perinatol. 12:1988;157-162
2. nd edition:2002;135-159 WB Saunders Co. Philadelphia
3. th edition:2004;505-518 WB Saunders Co. Philadelphia
4. Kalhan S.C., Parimi P., Van Beek R., et al. Estimation of gluconeogenesis in newborn infants. Am J Physiol Endocrinol Metab. 281:2001;E991-E997
5. Hume R., McGeechan A., Burchell A. Developmental disorders of glucose metabolism in infants. Child Care Health Dev. 28(Suppl 1):2002;45-47
6. Bazaes R.A., Salazar T.E., Pittaluga E., et al. Glucose and lipid metabolism in small for gestational age infants at 48 hours of age. Pediatrics. 111:2003;804-809
7. Stanley C.A. Dissecting the spectrum of fatty acid oxidation disorders. J Pediatr. 132:1998;384-386
8. Hawdon J.M. Hypoglycaemia and the neonatal brain. Eur J Pediatr. 158(Suppl 1):1999;S9-S12
9. Menni F., deLonlay P., Sevin C., Touati G., Peigne C., Barbier V., et al. Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia. Pediatrics. 3:2001;476-479
10. Stanley C.A., Baker L. The causes of neonatal hypoglycemia. N Engl J Med. 340:1999;1200-1201
11. Sperling M.A., Menon R.K. Hyperinsulinemic hypoglycemia of infancy: recent insights into ATP-sensitive potassium channels, sulfonylurea receptors, molecular mechanisms, and treatments. Endocrinol Metab Clin North Am. 4:1999;695-708
12. Fraser R. Managing diabetes in pregnancy. Practitioner. 246:2002;325-330
13. Clark W., O'Donovan D. Transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. Am J Perinatol. 4:2001;175-178
14. Bhowmick S.K., Lewandowski C. Prolonged hyperinsulinism and hypoglycemia in an asphyxiated, small for gestation infant: case management and literature review. Clin Pediatr. 12:1989;575-578
15. ATP channel or glutamate dehydrogenase. Pediatr Res. 53:2003;155A
16. Wolfsdorf J.I., Holm I.A., Weinstein D.A. Glycogen storage disease: phenotypic, genetic and biochemical characteristics, and therapy. Endocrinol Metab Clin North Am. 4:1999;801-823
17. Wolfsdorf J.I., Weinstein D.A. Glycogen storage diseases. Rev Endocr Metab Disord. 4:2003;95-102
18. deLonlay-Debeney P., Poggi-Travert F., Fournet J.C., Sempoux C., Vici C.D., Brunelle F., et al. Clinical features of 52 neonates with hyperinsulinism. N Engl J Med. 15:1999;1169-1175
19. deLonlay P., Fournet J.C., Touati G., Groos M.S., Martin D., Sevin C., et al. Heterogeneity of persistent hyperinsulinemic hypoglycaemia: a series of 175 cases. Eur J Pediatr. 1:2002;37-48
20. Aguilar-Bryan L., Nichols C.G., Wechsler S.W., et al. Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. Science. 268:1995;423-426
21. + channels. Science. 268:1995;372-373
22. + conduction and selectivity. Science. 280:1998;69-77
23. Thomas P.M., Cote G.J., Wohlik N., et al. Mutations in sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science. 268:1995;426-429
24. Thomas P., Ye Y., Lightner E. Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy. Hum Mol Genet. 5:1996;1809-1812
25. deLonlay P., Touati G., Robert J.J., Saudubray J.M. Persistent hyperinsulinaemic hypoglycaemia. Semin Neonatol. 1:2002;95-100
26. Ferry R.J., Kelly A., Grimberg A., et al. Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism. J Pediatr. 137:2000;239-246
27. Kelly A., Ng D., Ferry R.J. Jr., Grimberg A., Koo-McCoy S., Thornton P.S., et al. Acute insulin responses to leucine in children with hyperinsulinism/hyperammonemia syndrome. J Clin Endocrinol Metab. 8:2001;3724-3728
28. Stanley C.A., Thornton P.S., Ganguly A., et al. Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation. J Clin Endocrinol Metab. 89:2004;288-296
29. Beiervert C., Schroeder B.C., Kubisch C., et al. A potassium channel mutation in neonatal human epilepsy. Science. 279:1998;403-406
30. Marban E. The surprising role of vascular K (ATP) channels in vasospastic angina. J Clin Invest. 2:2002;153-154
31. Yamada K., Ji J.J., Yuan H., Miki T., Sato S., Horimoto N., et al. Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science. 292:2001;1543-1546
32. Aguilar-Bryan L., Bryan J. Molecular biology of adenosine triphosphate-sensitive potassium channels. Endocr Rev. 2:1999;101-135
33. Aguilar-Bryan L., Bryan J., Nakazaki M. Of mice and men: K(ATP) channels and insulin secretion. Recent Prog Horm Res. 56:2001;47-68
34. de Lonlay P., Cuer M., Vuillaumier-Barrot S., Beaune G., Castelnau P., Kretz M., et al. Hyperinsulinemic hypoglycemia as a presenting sign in phosphomannose isomerase deficiency: a new manifestation of carbohydrate- deficient glycoprotein syndrome treatable with mannose. J Pediatr. 3:1999;379-383
35. Menon R.K., Sperling M.A. Insulin as a growth factor. Endocrinol Metab Clin North Am. 3:1996;633-647
36. Levitt Katz L.E., Satin-Smith M.S., Collett-Solberg P., Thornton P.S., Baker L., Stanley C.A., et al. Insulin-like growth factor binding protein-1 levels in diagnosis of hypoglycemia caused by hyperinsulinism. J Pediatr. 2:1997;171-173
37. Chigot V., DeLonlay P., Nassogne M.C., Laborde K., Delagne V., Fournet J.C., et al. Pancreatic arterial calcium stimulation in the diagnosis and localization of persistent hyperinsulinemic hypoglycaemia of infancy. Pediatr Radiol. 9:2001;650-655
38. Verkarre V., Fournet J.C., deLonlay P., Gross-Morand M.D., Devillers M., Rahier J., et al. Paternal mutation of the sulfonylurea receptor (SUR1) gene and maternal loss of 11p15 imprinted genes lead to persistent hyperinsulinism in focal adenomatous hyperplasia. J Clin Invest. 7:1998;1286-1291
39. DeLonlay P., Fournet J.C., Rahier J., Gross-Morand M.S., Poggi-Travert F., Foussier V., et al. Somatic deletion of the imprinted 11p15 region in sporadic persistent hyperinsulinemic hypoglycemia of infancy is specific of focal adenomatous hyperplasia and endorses partial pancreatectomy. J Clin Invest. 4:1997;802-807
40. Seino S., Iwanaga T., Nagashima K., Miki T. Diverse roles in K(ATP) channels learned from Kir6.2 genetically engineered mice. Diabetes. 3:2000;311-318
41. Huopio H., Reimann F., Ashfield R., Komulainen J., Lenko H.L., Rahier J., et al. Dominantly inherited hyperinsulinism caused by a mutation in sulfonylurea receptor type 1. J. Clin Invest. 7:2000;897-906
42. Straub S.G., Cosgrove K.E., Ammala C., Shepherd R.M., O'Brein R.E., Barnes P.D., et al. Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways. Diabetes. 2:2001;329-339
43. Clayton P.T., Eaton S., Aynley-Green A., Edginton M., Hussain K., Krywawych S. Hyperinsulinism in short-chain 1-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion. J Clin Invest. 3:2001;457-465
44. Thorton P.S., Satin-Smith M.S., Herold K., Glaser B., Chiu K.C., Nestorowicz A., et al. Familial hyperinsulinism with apparent autosomal dominant inheritance: clinical and genetic differences from autosomal recessive variant. J Pediatr. 1:1998;9-14
45. Polychronakos C. New insights into the genetics of neonatal diabetes. Rev Endocr Metab Disord. 1:2003;19-22
46. Glaser B., Kesavan P., Heyman M., Davis E., Cuesta A., Buchs A., et al. Familial hyperinsulinism caused by an activating glucokinase mutation. N Engl J Med. 4:1998;226-230
47. Stanley C.A., Lieu Y.K., Hsu B.Y., et al. Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene. N Engl J Med. 19:1998;1352-1357
48. Huijmans J.G., Duran M., deKlerk J.B., Rovers M.J., Scholte H.R. Functional hyperactivity of hepatic glutamate dehydrogenase as a cause of the hyperinsulinism/hyperammonemia syndrome: effect of treatment. Pediatrics. 3:2000;596-600
49. Miller B.S., Freeze H.H. New disorders in carbohydrate metabolism: congenital disorders of glycosylation and their impact on the endocrine system. Rev Endocr Metab Disord. 1:2003;103-113