Functional Properties of Recombinant Factor V Mutated in a Potential Calcium-Binding Site

Biochemistry

Volumn 43, Issue 19, 2004, Pages 5803-5810

  Sørensen, Kristoffer W ^a,b   Nicolaes, Gerry A F ^b   Villoutreix, Bruno O ^c   Yamazaki, Tomio ^a,d   Tans, Guido ^b   Rosing, Jan ^b   Dahlbäck, Bjöm ^a  

^a LUND UNIVERSITY   (Sweden)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c INSERM   (France)

^d NATIONAL HOSPITAL ORGANIZATION NAGOYA MEDICAL CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CALCIUM; CATALYSIS; CHEMICAL ACTIVATION; IONIC STRENGTH; LIQUID CHROMATOGRAPHY; PHOSPHOLIPIDS;

HEAVY CHAIN (HC); INCUBATION; PROTHROMBIN ACTIVATION; RECOMBINANT FACTORS;

BIOCHEMISTRY;

ASPARAGINE; ASPARTIC ACID; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5; CALCIUM; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; PROTHROMBIN; RECOMBINANT FACTOR 5; THROMBIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHROMATOGRAPHY; DISSOCIATION; DOSE RESPONSE; ENZYME ACTIVE SITE; IONIC STRENGTH; NUCLEOTIDE SEQUENCE; PHOSPHOLIPID VESICLE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; ASPARAGINE; BINDING SITES; BLOOD COAGULATION TESTS; CALCIUM-BINDING PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; DIMERIZATION; FACTOR V; FACTOR VA; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN SUBUNITS; PROTHROMBIN; RECOMBINANT PROTEINS; SOLUTIONS;

EID: 2442425637     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0361362     Document Type: Article

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