Alteration of β-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes

Molecular and Cellular Endocrinology

Volumn 219, Issue 1-2, 2004, Pages 77-82

  Novelli, M ^a   Pocai, A ^a   Lajoix, A D ^b   Beffy, P ^c   Bezzi, D ^a   Marchetti, P ^a   Gross, R ^b   Masiello, P ^a  

^a UNIVERSITY OF PISA   (Italy)

^b CNRS   (France)

^c INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

Author keywords

Arginine; Constitutive nitric oxide synthase; Experimental diabetes; Insulin secretion; Isolated islets

Indexed keywords

ARGININE; GLUCOSE; INSULIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; IN VITRO STUDY; INSULIN RELEASE; INSULIN RESPONSE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; ARGININE; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GLUCOSE; INSULIN; ISLETS OF LANGERHANS; ISOENZYMES; MALE; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR;

EID: 2442419666     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2004.01.010     Document Type: Article

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