Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: Cluster randomised controlled trial

British Medical Journal

Volumn 331, Issue 7515, 2005, Pages 478-481

  Crump, John A ^a   Otieno, Peter O ^b   Slutsker, Laurence ^b   Keswick, Bruce H ^c   Rosen, Daniel H ^b   Hoekstra, R Michael ^a   Vulule, John M ^d   Luby, Stephen P ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c PROCTER AND GAMBLE COMPANY   (United States)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORINE; DISINFECTANT AGENT;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISINFECTION; ESCHERICHIA COLI; HOUSEHOLD; HUMAN; HUMAN TISSUE; INFANT; INFECTION PREVENTION; INTERMETHOD COMPARISON; KENYA; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; TURBIDITY; WATER CONTAMINATION;

ADOLESCENT; ADULT; AGED; CLUSTER ANALYSIS; DIARRHEA; DISINFECTANTS; FEMALE; FLOCCULATION; HUMANS; INFANT; INFANT, NEWBORN; KENYA; MALE; MIDDLE AGED; PREVALENCE; RURAL HEALTH; SODIUM HYPOCHLORITE; WATER PURIFICATION; WATER SUPPLY;

EID: 24344507360     PISSN: 09598146     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.38512.618681.E0     Document Type: Article

References (13)

1. Quick RE, Venczel LV, Mintz ED, Soleto L, Aparicio J, Gironaz M, et al. Diarrhoea prevention in Bolivia through point-of-use water treatment and safe storage: a promising new strategy. Epidemiol Infect 1999;122:83-90.
2. Quick RE, Kimura A, Thevos A, Tembo M, Shamputa I, Hutwagner L, et al. Diarrhea prevention through household-level water disinfection and safe storage in Zambia. Am J Trop Med Hyg 2002;66:584-9.
3. Reller ME, Mendoza CE, Lopez MB, Alvarez M, Hoekstra RM, Olson CA, et al. A randomized controlled trial of household based flocculent-disinfectant drinking water treatment for diarrhea prevention in rural Guatemala. Am J Trop Med Hyg 2003;69:411-9.
4. Semenza JC, Roberts L, Henderson A, Bogan J, Rubin CH. Water distribution system and diarrheal disease transmission: a case study in Uzbekistan. Am J Trop Med Hyg 1998;59:941-6.
5. Crump JA, Okoth GO, Slutsker L, Ogaja DO, Keswick BH, Luby SP. Effect of point-of-use disinfection, flocculation, and combined flocculation-disinfection on drinking water quality in western Kenya. J Appl Microbiol 2004;97:225-31.
6. Meinhardt PL, Casemore DP, Miller KB. Epidemiologic aspects of human cryptosporidiosis and the role of waterborne transmission. Epidemiol Rev 1996;18:118-36.
7. Rangel JM, Lopez B, Mejia MA, Mendoza C, Luby S. A novel technology to improve drinking water quality: a microbiological evaluation of in-home flocculation and chlorination in rural Guatemala. J Water Health 2003;1:15-22.
8. Souter PF, Cruickshank GD, Tankerville MZ, Keswick BH, Ellis BD, Langworthy DE, et al. Evaluation of a new water treatment for point-of-use household applications to remove microorganisms and arsenic from drinking water. J Water Health 2003;1:73-84.
9. Phillips-Howard PA, Nahlen BL, Kolczak MS, Hightower AW, Ter Kuile FO, Alaii JA, et al. Efficacy of permethrin-treated bed nets in the prevention of mortality in young children in an area of high perennial malaria transmission in western Kenya. Am J Trop Med Hyg 2003;68(suppl 4):23-9.
10. Makutsa P, Nzaku K, Ogutu P, Barasa P, Ombeki S, Mwaki A, et al. Challenges to implementing a point-of-use water quality intervention in rural Kenya. Am J Public Health 2001;91:1571-3.
11. Morris SS, Cousens SN, Kirkwood BR, Arthur P, Ross DA. Is prevalence of diarrhea a better predictor of subsequent mortality and weight gain than diarrhea incidence? Am J Epidemiol 1996;144:582-8.
12. Mintz ED, Reiff FM, Tauxe RV. Safe water treatment and storage in the home: a practical new strategy to prevent waterborne disease. JAMA 1995;273:948-53.
13. Stanton B, Black RE, Engle P, Pelto G. Theory-driven behavioral intervention research in the control of diarrheal diseases. Soc Sci Med 1992;35:1405-20.