Synthesis of new carbo- and heterocyclic analogues of 8-HETE and evaluation of their activity towards the PPARs

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4421-4426

  Caijo, Frédéric ^a   Mosset, Paul ^a   Grée, René ^b   Audinot Bouchez, Valérie ^d   Boutin, Jean ^d   Renard, Pierre ^c   Caignard, Daniel Henri ^d   Dacquet, Catherine ^c  

^a UNIV RENNES   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

^d INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

8 HETE; Dual agonists; PPARs; Quinoline

Indexed keywords

CARBOHYDRATE DERIVATIVE; HETEROCYCLIC COMPOUND; HYDROXYICOSATETRAENOIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIRINIXIC ACID; QUINOLINE DERIVATIVE; ROSIGLITAZONE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; COS CELLS; DRUG EVALUATION, PRECLINICAL; HYDROXYEICOSATETRAENOIC ACIDS; PPAR ALPHA; PPAR GAMMA;

EID: 24344502706     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.07.049     Document Type: Article

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