Further evidence supporting the use of sodium oxybate for the treatment of cataplexy: A double-blind, placebo-controlled study in 228 patients

Sleep Medicine

Volumn 6, Issue 5, 2005, Pages 415-421

  Ahmed, Mansoor ^a,b   Bassetti, Claudio ^a,c   Becker, Philip ^a,d   Michael, Biber ^a,e   Black, Jed ^a,f   Bogan, Richard ^a,g   Chesson Jr , Andrew ^a,h   Cook, James ^a,i   Duntley, Stephen ^a,j   Emsellem, Helene ^a,k   Ermine, Milton ^a,l   Hayduk, Roza ^a,l   Feldman, Neil ^a,m   Fleming, John ^a,n   Geisler, Peter ^a,o   Hagaman, Martha ^a,p   Hill, Dennis ^a,q   Houghton, William C ^a   Hornfeldt, Carl S ^a   Husain, Aatif M ^a,r   Kaelin, Thomas ^a,s   Lammers, Gert Jan ^a,t   Lankford, D Alan ^a,u   Leech, Judith ^a,v   Mamelak, Mortimer ^a,w   Mayer, Geert ^a,x   Moldofsky, Harvey ^a,y   Montplaisir, Jacques ^a,z   Morehouse, Rachel ^a,aa   Moscovitch, Adam ^a,ab   Nevsimalova, Sona ^a,ac   Sonka, Karel ^a,ac   Orr, William ^a,ad   Pascualy, Ralph ^a,ae   Pegram, Vernon ^a,af   Perkins, Thomas ^a,ag   Phadke, Jayant ^a,ah   Ristanovic, Ruzica ^a,ai   Shneerson, John ^a,aj   Stevens, James ^a,ak   Swick, Todd ^a,al   Walsleben, Joyce ^a,am   Walter, Timothy ^a,an   Ware, J Catesby ^a,ao   Whitten, Patrick ^a,ak   Winslow, David ^a,ap   more..

^a JAZZ PHARMACEUTICALS   (United States)

^b Cleveland Sleep Research Center   (United States)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d Sleep Medicine Associates of Texas PA   (United States)

^e Center for Sleep Diagnostics   (United States)

^f STANFORD UNIVERSITY   (United States)

^g Baptist Medical Center   (United States)

^h LOUISIANA STATE UNIVERSITY   (United States)

ⁱ The Center for Sleep and Wake Disorders   (United States)

^j WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k Center for Sleep and Wake Disorders   (United States)

^l Pacific Sleep Medicine Services   (United States)

^m St Petersburg Sleep Disord Center   (United States)

ⁿ VANCOUVER GENERAL HOSPITAL   (Canada)

^o UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^p Children's Sleep Institute   (United States)

^q Central Carolina Neurology and Sleep   (United States)

^r DUKE UNIVERSITY   (United States)

^s Lowcountry Lung and Critical Care PA   (United States)

^t LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^u Sleep Disorders Center of Georgia   (United States)

^v UNIVERSITY OF OTTAWA   (Canada)

^w Brain and Sleep Diagnostic Center   (Canada)

^x Hephata Klinik   (Germany)

^y Centre for Sleep and Chronobiology   (Canada)

^z Sleep Disorder Centre   (Canada)

^aa SAINT JOHN REGIONAL HOSPITAL   (Canada)

^ab Canadian Sleep Institute   (Canada)

^ac CHARLES UNIVERSITY   (Czech Republic)

^ad LYNN HEALTH SCIENCE INSTITUTE   (United States)

^ae Swedish Sleep Medicine Institute   (United States)

^af Sleep Disorders Center of Alabama   (United States)

^ag Raleigh Neurology Associates   (United States)

^ah SAINT VINCENT HOSPITAL   (United States)

^ai EVANSTON HOSPITAL   (United States)

^aj PAPWORTH HOSPITAL   (United Kingdom)

^ak The Houston Sleep Center ^*

^al The Houston Sleep Center   (United States)

^am BELLEVUE HOSPITAL CENTER   (United States)

^an Grove City Sleep Diagnostic Center   (United States)

^ao Sleep Disorders Center   (United States)

^ap Sleep Medicine Specialists   (United States)

more..

Author keywords

Cataplexy; Gamma hydroxybutyrate; Narcolepsy; Sodium oxybate

Indexed keywords

OXYBATE SODIUM; PLACEBO; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BACKACHE; CATAPLEXY; CHILL; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONTUSION; DISEASE SEVERITY; DIZZINESS; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG ELIMINATION; DRUG FEVER; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; DRUG USE; DRUG WITHDRAWAL; DRUNKENNESS; DYSARTHRIA; DYSPNEA; ENURESIS; EYE IRRITATION; FALLING; FEMALE; HUMAN; LIVER TOXICITY; MAINTENANCE DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MUSCLE CRAMP; NARCOLEPSY; NAUSEA; PATIENT MONITORING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SLEEP WALKING; SNORING; SOMNOLENCE; STATISTICAL SIGNIFICANCE; TITRIMETRY; TREATMENT OUTCOME; TREMOR; VERTIGO;

EID: 24344500187     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2005.03.010     Document Type: Article

References (8)

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2. M. Scharf D. Brown M. Woods et al. The effects and effectiveness of γ-hydroxybutyrate in patients with narcolepsy J Clin Psychol 46 1985 222-225
3. L. Scrima P.G. Hartman F.H. Johnson Jr F.C. Hiller Efficacy of gamma-hydroxybutyrate versus placebo in treating narcolepsy-cataplexy: double-blind subjective measures Biol Psychol 26 1989 331-343
4. G.J. Lammers J. Arends A.C. Declerck et al. Gamma-hydroxybutyrate and narcolepsy: A double-blind placebo-controlled study Sleep 16 1993 216-220
5. US Xyrem® Multicenter Study Group A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy Sleep 25 2002 42-49
6. US Xyrem® Multicenter Study Group Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy Sleep Med 5 2004 119-123
7. US Xyrem® Multicenter Study Group A 12-month, open-label, multi-center extension trial of orally administered sodium oxybate for the treatment of narcolepsy Sleep 26 2003 31-35
8. C. Bassetti M.S. Aldrich Narcolepsy Neurol Clin 14 1996 545-571