Delays and treatment interruptions: Difficulties in administering radiotherapy in an ideal time-period;Retrasos e interrupciones: la dificultad para irradiar en el tiempo ideal

Clinical and Translational Oncology

Volumn 7, Issue 2, 2005, Pages 47-54

  San Segundo, Carmen González ^a   Calvo Manuel, Felipe A ^a   Santos Miranda, Juan Antonio ^a  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

Delay; Interruption; Radiotherapy; Total time treatment

Indexed keywords

HUMAN; METHODOLOGY; RADIOTHERAPY; REVIEW; STANDARD; TIME;

HUMANS; RADIOTHERAPY; TIME FACTORS;

EID: 24344457709     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/BF02710009     Document Type: Review

References (75)

1. Wyatt RM, Beddoe AH, Dale RG. The effects of delays in radiotherapy treatment on tumour control. Phys Med Biol. 2003;48:139-55.
2. Fowler J, Lindstrom MJ. Loss of local control with prolongation in radiotherapy. Int J Radiat Oncol Biol Phys. 1992;23:457-67.
3. Schiff PB, Harrison LB, Strong EW, et al. Impact of the time interval between surgery and postoperative radiation therapy on locoregional control in advanced head and neck cancer. J Surg Oncol. 1990;43:203-8.
4. Allal AS, de Pree C, Dulguerov P, Bieri S, Maire D, Kurtz JM. Avoidance of treatment interruption: an unrecognized benefit of accelerated radiotherapy in orop-haryngeal carcinomas? Int J Radiat Oncol Biol Phys. 1999;45:41-5.
5. Jones TM, Hargrove O, Lancaster J, Fenton J, Shenoy A, Roland NJ. Waiting times during the management of head and neck tumours. J Laryngol Otol. 2002;116:275-9.
6. Chatani M, Matayoshi Y, Masaki N, Teshima T, Inoue T. Radiation therapy for early glottic carcinoma (T1N0M0). The adverse effect of treatment interruption. Strahlent-her Onkol. 1997;173:502-6.
7. Duncan W, MacDougall H, Kerr G, Downing D. The adverse effect of treatment gaps in the outcome of radiotherapy for laryngeal cancer. Radiother Oncol. 1996; 41:203-7
8. James ND, Robertson G, Squire CJ, et al. A national audit of radiotherapy in head and neck cancer. Clin Oncol. 2003;15:41-6.
9. Petereit DG, Sarkaria N, Chappell R, et al. The adverse effect of treatment prolongation in cervical carcinoma. Int J Radiat Oncol Biol Phys. 1995;32:1301-7
10. Girinsky T, Rey A, Roche B, et al. Overall treatment time in advanced cervical carcinomas. A critical parameter in treatment outcome. Int J Radiat Oncol Biol Phys. 1994; 27:1051-6.
11. Chen SW, Liang JA, Yang SN, Ko HL, Lin FJ. The adverse effect of treatment prolongation in cervical cancer by high-dose-rate intracavitary brachytherapy. Radiother Oncol. 2003;67:69-76.
12. Erridge SC, Kerr GR, Downing D, Duncan W, Price A. The effect of overall treatment time on the survival and toxicity of radical radiotherapy for cervical carcinoma. Radiother Oncol. 2002;63:59-66.
13. Benk V, Joseph L, Fortin P, et al. Effect of delay in initiating radiotherapy for patients with early stage breast cancer. Clin Oncol. 2004;16:6-11.
14. Metz JM, Schultz DJ, Fox K, Mathews A, Glick J, Solin LJ. Analysis of outcomes for high-risk breast cancer based on interval from surgery to postmastectomy radiation therapy. Cancer J. 2000;6:324-30.
15. Meek AG, Park TL, Weiss TA, et al. Effect of delayed radiation therapy on local control in breast conservation therapy. Radiology. 1996;200:615-9.
16. Harari PM, Fowlwe JF. Idealised versus realised overall treatment times. Int J Radiat Oncol Biol Phys. 1994;29: 209-11.
17. Skadowski K, Law MG, Maciejewski B, Steel GG. Planned and unplanned gaps in radiotherapy: the importance of gap position and gap duration. Radiother Oncol. 1994;30:109-20.
18. Palacios A, Escó R, López C, Petschen I. Situación de la Asistencia Oncológica: Oncología Radioterápica. En: Biete A, Muñoz A, editores. Tercer Libro Blanco de la Oncología en España. FESEO. Madrid: Ed. Ergon; 2002. p.61-91.
19. Porter A, Aref A, Chodounsky Z, et al. A global strategy for radiotherapy: a WHO consultation. Clin Oncol. 1999; 11:368-70.
20. Biete A, Palacios A, Calvo FA, editores. Gestión Clínica en Oncología Radioterápica. Madrid: AERO; 2003.
21. Carceller JA, López J, Petschen I, et al. Situación y re-cursos de la Oncología Radioterápica en España. En: Escó R, Palacios A, editores. Situación y recursos de la Oncología Radioterápica en España. Madrid: 2002.
22. Carroquino M, Escó R. Cálculo de costes de los tratamien-tos de radioterapia con unidades de megavoltaje basados en las actividades. Zaragoza: Proceso Gráfico Total; 1998.
23. Benk V, Levinton C, Fortin PR, et al. Effect of delay in initiating radiotherapy for patients with early stage breast cancer: results of a natural experiment. Int J Radiat Oncol Biol Phys. 1999;45:305-6.
24. Vujovic O, Perera F, Dar AR, et al. Does delay in breast irradiation following conservative breast surgery in node-negative breast cancer patients have an impact on risk of recurrence? Int J Radiat Oncol Biol Phys. 1998; 40:869-74.
25. Harstell WF, Recine DC, Griem KL, et al. Delaying the initiation of intact breast irradiation for patients with lymph node positive breast cancer increases the risk of local recurrence. Cancer. 1995;76:2497-503.
26. Froud PJ, Mates D, Jackson JS, et al. Effect of time interval between breast-conserving surgery and radiation therapy on ipsilateral breast recurrence. Int J Radiat Oncol Biol Phys. 2000;46:363-72.
27. Nixon AJ, Recht A, Neuberg D, et al. The relation between the surgery-radiotherapy interval and treatment outcome in patients treated with breast-conserving surgery and radiation therapy without systemic therapy. Int J Radiat Oncol Biol Phys. 1994;30:17-21.
28. Ampil FL, Burton GV, Li BD, et al. Radiotherapy with and without chemotherapy after breast conservation surgery for early stage breast cancer: a review of timing. Eur J Gynaecol Oncol. 1999;20:254-7
29. Kajanti M, Holsti LR, Holsti P. Radical surgery and postoperative split-course radiotherapy in squamous cell carcinoma of the mobile tongue: factors influencing local control and the time to recurrence. Radiother Oncol. 1991;22:174-9.
30. Bastit L, Blot E, Debourdeau P, et al. Influence of the delay of adjuvant postoperative radiation therapy on relapse and survival in oropharyngeal and hypopharyngeal cancers. Int J Radiat Oncol Biol Phys. 2001;49:139-46.
31. Huang J, Barbera L, Brouwers M, Browman G, Macki-llop WJ. Does delay in starting treatment affect the outcomes of radiotherapy? A systematic review. J Clin Oncol. 2003;21:555-63.
32. Ampil FL, Sanghani SV. Timing of radiotherapy in asymptomatic patients with inoperable non-small cell lung cancer: a survival analysis and literature review. Radiat Med. 1996;14:211-4.
33. Wurschmidt F, Bunemann H, Ehnert M, et al. Is the time interval between surgery and radiotherapy important in operable non-small cell lung cancer? A retrospective analysis of 340 cases. Int J Radiat Oncol Biol Phys. 1997; 39:553-9.
34. Ballo MT, Zagars GK, Cormier JN, et al. Interval between surgery and radiotherapy: effect on local control of soft tissue sarcoma. Int J Radiat Oncol Biol Phys. 2004; 58:1461-7
35. Schwartz DL, Einck J, Hunt K, et al. The effect of delayed postoperative irradiation on local control of soft tissue sarcomas of the extremity and torso. Int J Radiat Oncol Biol Phys. 2002;52:1352-9.
36. Do V, Gebski V, Barton MB. The effect of waiting for radiotherapy for grade III/IV gliomas. Radiother Oncol. 2000;57:131-6.
37. González C, Santos JA, Cuesta P. Comment on: The effect of waiting for radiotherapy for grade III/IV gliomas. Radiother Oncol. 2001;60:333-6.
38. McGowan DG. The influence of treatment delay in carcinoma of the prostate treated by external beam radiation therapy. Clin Invest Med. 2000;23:32-6
39. The Medical Research Council Prostate Cancer Working Party Investigators Group. Inmediate versus deferred treatment for advanced prostatic cancer: initial results of the Medical Research Council trial. Br J Urol. 1997; 79:235-46.
40. Jeremic B, Shibamoto Y, Acinovic L, et al. Initial vs. delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited stage small-cell lung cancer: a randomised study. J Clin Oncol. 1997;15:893-900.
41. Del Valle ML, Sanz A, Garavis M, Rey P, López-Lara F. Radioterapia en el cáncer microcítico de pulmón: ¿cuánto antes mejor? Oncología. 2000;23:117-25.
42. Takada M, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the Japan Clinical Oncology Group Study 9104. J Clin Oncol. 2002;20:3054-60
43. Real Decreto sobre Control de Calidad en Radioterapia 1566/1598 de 17 de julio de 1998.
44. Parker C, Warde P, Catton C. Salvage radiotherapy for PSA failure after radical prostatectomy. Radiother Oncol. 2001;61:107-16.
45. Van Cangh P, Richard F, Lorge F, et al. Adjuvant radiation therapy does not cause urinary incontinence after radical prostatectomy: Results of a prospective randomized study. J Urol. 1998;159:164-6.
46. Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer. Lancet. 2000;355:949-55
47. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials. Neoad-juvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration. Eur J Cancer. 2003;39:2470-86.
48. a ed. Madrid: McGraw-Hill Interamericana; 1998.p.341-56.
49. Coles CE, Burgess L, Tan LT. An audit of delays before and during radical radiotherapy for cervical cancer: effect on tumour cure probability. Clin Oncol. 2003;15:47-54.
50. Lindberg RD, Jones K, Garner HH, Jose B, Spanos WJ, Bhatnaga S. Evaluation of unplanned interruptions in radiotherapy treatment schedules. Int J Radiat Oncol Biol Phys. 1988;14:811-5.
51. Khalil AA, Bentzen SM, Bernier J et al. Compliance to the prescribed dose and overall treatment time in five randomized clinical trials of altered fractionation in radiotherapy for head-and-neck carcinomas. Int J Radiat Oncol Biol Phys. 2003;55:568-75.
52. Buchanan R. Guidelines for the management of the unscheduled interruption or prolongation of a radical course of Radiotherapy. 2nd ed. The Royal College of Radiologists; 2002.p.1-23.
53. Macia M, Solé J, Cambra M, Peraire M, Pardo J, Macias V. Evaluation of unplanned interruptions in curative radiotherapy: a GICOR descriptive study on compilanse to the prescribed overall treatment time in normal radiotherapy practice. Int J Radiat Oncol Biol Phys. 2003;57, (suppl. 2): S444
54. Procedimientos recomendados para la dosimetría de fo-tones y electrones de energías comprendidas entre 1 MeV y 50 MeV en radioterapia de haces externos. Socie-dad Española de Física Médica. Publicación n° 1, 1984
55. Suplemento al documento SEFM n° 1, 1984. Sociedad Española de Física Médica. Publicación n° 1, 1987
56. Milecki P, Kruk-Zagajewska A. Time factors in postoperative radiotherapy in the years 1986-1999 and 2000-2002. Otoraryngol Pol. 2003;57:483-7
57. Leon X, de Vega M, Orus C, Moran J, Verges J, Quer M. The effect of waiting time on local control and survival in head and neck carcinoma patients treated with radiotherapy. Radiother Onco. 2003;66:277-81.
58. Kwong Dl, Sham JS, Chua DT, Choy DT, Au GK, Wu PM. The effect of interruption and prolonged treatment time in radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 1997;39:703-10.
59. Milecki P, Kruk-Zagajewska A, Stryczynska G. Timing and duration of postoperative radiotherapy in patients with laryngeal cancer. Otoraryngol Pol. 2002;56:307-11.
60. Bhattathiri VN. Cumulative interfraction interval analysis of time and fraction size in radiotherapy. Clin Oncol. 2003;15:394-9.
61. Nag S, Erickson B, Thomadsen B, et al. The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys. 2000;48:201-11.
62. Jeremic B, Shibamoto Y, Milicic B, et al. Impact of treatment interruptions due to toxicity on outcome of patients with early stage (I/II) non-small-cell luna cancer (NSCLC) treated with hyperfractionated radiation therapy alone. Lung Cancer. 2003;40:317-23.
63. Chen M, Jiang GL, Fu XL, et al. The impact of overall treatment time on outcome in radiation therapy for non-small cell lung cancer. Lung Cancer. 2000;28:11-9.
64. Vidatic GM, Fung K, Tomiak AT, et al. Using treatment interruptions to palliate the toxicity from concurrent chemoradiation for limited small cell lung cancer decreases survival and disease control. Lung Cancer. 2001;33:259-58.
65. Moonen L, Vd Voet H, de Nijs R, Horenblas S, Hart AA, Bartelink H. Muscle-invasive bladder cancer treated with external beam radiation: influence of total dose, overall treatment time, and treatment interruption on local control. Int J Radiat Oncol Biol Phys. 1998;42:525-30.
66. Leighton C, Fisher B, Bauman G, et al. Supratentorail low-grade glioma in adults: an analysis of prognostic factors and timing of radiation. J Clin Oncol. 1997; 15:1294-301.
67. Fein DA, Lee WR, Lanciano RM, et al. Management of extremity soft tissue sarcomas with limb-sparing surgery and postoperative irradiation: do total dose, overall treatment time, and the surgery-radiotherapy interval impact on local control? Int J Radiat Oncol Biol Phys. 1995;32:969-76.
68. Lehman M, Jacob S, Delaney G, et al. Waiting times for radiotherapy-a survey of patients' attitudes. Radiother Oncol. 2004;70:283-9.
69. Fowler JF. The linear-quadratic model and progress in radiotherapy. Br J Radiol. 1989;62:679-94.
70. Waaijer A, Terhaard CH, Dehnad H, et al. Waiting times for radiotherapy: consequences of volume increase for the TCP in oropharyngeal carcinoma. Radiother Oncol. 2003;66:271-6.
71. Dale RG, Hendry JH, Jones B, Robertson AG, Deehan C, Sinclair JA. Practical methods for compensating for missed treatment days in radiotherapy with particular reference to head and neck schedules. Clin Oncol. 2002; 14:382-93.
72. Baumann M, Herrman T. Management of the unscheduled interruption or prolongation of a radical course of radiotherapy. Strahlenther Onkol. 1999;174:491-3.
73. Hendry JH, Bentzen SM, Dale RG, et al. A modelled comparison of the effects of using different ways to compensate for missed treatment days in radiotherapy. Clin Oncol. 1996;8:297-307
74. Dale RG. Time dependent tumour repopulation factors in linear-quadratic quations. Implications for treatment strategies. Radiother Oncol. 1989;15:371-82.
75. Read G. Radiotherapy: effective treatment at low cost. Clin Oncol. 1995;7:275-6.