Direct separation of the enantiomers of (±)-metoprolol tartrate on impregnated TLC plates with D-(-)-tartaric acid as a chiral selector

Journal of Planar Chromatography - Modern TLC

Volumn 18, Issue 104, 2005, Pages 294-299

  Lučić, Branka ^a   Radulović, Dušanka ^a   Vujić, Zorica ^a   Agbaba, Danica ^a  

^a Faculty of Pharmacy   (Serbia)

Author keywords

Chiral separation; D ( ) tartaric acid; Metoprolol tartrate; TLC

Indexed keywords

ADDITIVES; IMPREGNATION; ORGANIC ACIDS; SEPARATION; SILICA GEL;

CHIRAL MOBILE PHASE ADDITIVE; ENANTIOMERS; METOPROLOL TARTRATE;

THIN LAYER CHROMATOGRAPHY;

ALCOHOL; METOPROLOL TARTRATE; PRESOLOL; TARTARIC ACID; WATER;

ARTICLE; CHIRALITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENSITOMETRY; DRUG QUALITY; DRUG STRUCTURE; ENANTIOMER; QUALITATIVE ANALYSIS; SEPARATION TECHNIQUE; SPECTRAL SENSITIVITY; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

EID: 24344454332     PISSN: 09334173     EISSN: None     Source Type: Journal    
DOI: 10.1556/JPC.18.2005.4.8     Document Type: Article

References (26)

1. B. Koppenhoefer, X. Yhu, A. Jakob, S. Wuerthner, and B. Lin, J. Chromatogr. A 875 (2000) 135-161.
2. D. Burger and J. Abraham (Eds) Medicinal Chemistry and Drug Discovery, John Wiley and Sons, Hoboken, New Jersey, 2003.
3. W.O. Foye, D.A. Williams, and T.L. Lemke (Eds) Foye's Principles of Medicinal Chemistry, 5th edn, Lippincott, Williams and Wilkins, 2002.
4. X. Zhang, J. Ouyang, W.R.G. Baeyens, S. Zhai, Y. Yang, and G. Huang, J. Pharm. Biomed. Anal. 31 (2003) 1047-1057.
5. N.M. Maier and G. Uray, J. Chromatogr. A 740 (1996) 11-19.
6. P. Franco, C. Minguillon, and L. Oliveros, J. Chromatogr. A 791 (1997) 37-44.
7. X. Yang, T. Fukushima, T. Santa, H. Homma, and K. Imai, Analyst 11 (1997) 1365-1369.
8. H.Y. Aboul-Enein, L.I. Abou-Basha, and S.A. Bakr, Chirality 8 (1996) 153-156.
9. M.W. Matchett, S.K. Branch, and T.M. Jefferies, Chirality 8 (1996) 126-130.
10. B. Awadallah, P.C. Schmidt, U. Holzgrabe, and M.A. Wahl, Electrophoresis 24 (2003) 2627-2632.
11. G. Gübitz and M.G. Schmid, J. Chromatogr. A 792 (1997) 179-225.
12. S.L. Tamisier-Karolak, M.A. Stenger, and A. Bommart, Electrophoresis 20 (1999) 2656-2663.
13. A.M. Tivert and A. Backman, J. Planar. Chromatogr. 2 (1989) 472-473.
14. A.M. Tivert and A. Backman, J. Planar. Chromatogr. 6 (1993) 216-219.
15. R. Bhushan and M. Arora, Biomed. Chromatogr. 17 (2003) 226-230.
16. H.Y. Aboul-Enein, M.I. El-Awady, and C.M. Heard, Pharmazie 57 (2002) 169-171.
17. R. Bhushan and G.T. Thiongo, J. Chromatogr. B 708 (1998) 330-334.
18. R. Suedee, C. Songkram, A. Petmoreekul, S. Sangkunakup, S. Sankasa, and N. Kongyarit, J. Pharm. Biomed. Anal. 19 (1999) 519-527.
19. G. Pflugmann, H. Spahn, and E. Mutschler, J. Chromatogr. B 421 (1987) 161-164.
20. M. Ahnoff, S. Chen, A. Green, and I. Grundevik, J. Chromatogr. A 506 (1990) 593-599.
21. G. Pflugmann, H. Spahn, and E. Mutschler, J. Chromatogr. B 416 (1987) 331-339.
22. O. Gyllenhaal and A. Karlssom, J. Biochem. Biophys. Methods 54 (2002) 169-185.
23. R. Bhushan, J. Martens, and M. Arora, Biomed. Chromatogr. 15 (2001) 151-154.
24. R. Bhushan and M. Arora, Biomed. Chromatogr. 15 (2001) 433-436.
25. R. Bhushan and G.T. Thiongo, J. Planar Chromatogr. 13 (2000) 33-36.
26. R. Bhushan and G.T. Thiongo, Biomed. Chromatogr. 13 (1999) 276-278.