Slow internal release of bioactive compounds under the effect of skin enzymes

Journal of Investigative Dermatology

Volumn 125, Issue 2, 2005, Pages 270-277

  Redoulés, Daniel ^a   Perie, Jacques ^b   Viodé, Cécile ^a   Mavon, Alain ^a   Fournier, Didier ^c   Daunes, Sylvie ^a   Casas, Christiane ^a   Lougarre, Andreé ^c   De Viguerie, Nancy ^b  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

^c INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

Author keywords

Prodrugs; Recombinant glucocerebrosidase; Retinoic acid; Skin enzymes; Tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARBUTIN RETINOATE; BETA GLUCOCEREBROSIDASE; CERAMIDE; ESTERASE; GLUCOSIDASE; GLUCOSYLCERAMIDASE; GLYCEROL; GLYCOCONJUGATE; HYDROQUINONE; PRODRUG; RECOMBINANT ENZYME; RETINOIC ACID; RETINOIC ACID DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ARBUTIN;

ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME SYNTHESIS; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; HYDROLYSIS; NORMAL HUMAN; PRIORITY JOURNAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECT; EPIDERMIS; IN VITRO STUDY; KINETICS; METABOLISM; METHODOLOGY;

ALPHA-TOCOPHEROL; ANTIOXIDANTS; ARBUTIN; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; EPIDERMIS; GLUCOSYLCERAMIDASE; GLYCOCONJUGATES; HUMANS; HYDROLYSIS; KINETICS; TRETINOIN;

EID: 24344452586     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2005.23785.x     Document Type: Article

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