Survival, graft atherosclerosis, and rejection incidence in heart transplant recipients treated with statins: 5-Year follow-up

Journal of Heart and Lung Transplantation

Volumn 24, Issue 9, 2005, Pages 1235-1238

  Stojanovic, Ivan ^a   Vrtovec, Bojan ^a   Radovancevic, Branislav ^a,b   Radovancevic, Rajko ^a   Yazdanbakhsh, Aria P ^a   Thomas, Cynthia D ^a   Frazier, O H ^a  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b TEXAS HEART INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN; PREDNISONE;

ADULT; ARTICLE; CARDIAC GRAFT REJECTION; CAUSE OF DEATH; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; FEMALE; FOLLOW UP; HEART TRANSPLANTATION; HEMODYNAMICS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SURVIVAL RATE; SURVIVAL TIME; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; ATHEROSCLEROSIS; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; PRAVASTATIN; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 24344446890     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2004.08.014     Document Type: Article

References (18)

1. J. Kreuzer, J. Bader, L. Jahn, M. Hautmann, W. Kubler, E. Von Hodenberg Chemotaxis of the monocyte cell line U937 dependence on cholesterol and early mevalonate pathway products Atherosclerosis 90 1991 203 209
2. S. Katznelson, X.M. Wang, D. Chia The inhibitory effects of pravastatin on natural killer cell activity in vitro and cytotoxic T lymphocyte activity in vitro J Heart Lung Transplant 17 1998 335 340
3. J.L. Kakkis, B. Ke, S. Dawson Pravastatin increases survival and inhibits natural killer cell enhancement in liver transplanted rats J Surg Res 69 1997 393 398
4. R. McPherson, C. Tsoukas, M.G. Baines Effects of lovastatin on natural killer cell function and other immunological parameters in man J Clin Immunol 13 1993 439 444
5. J.L. Cutts, A.D. Bankhurst Reversal of lovastatin-mediated inhibition of natural killer cell cytotoxicity by interleukin 2 J Cell Physiol 145 1990 244 252
6. S. Katznelson, A. Ramirez, R. Perez, R. Weiss Pravastatin and cyclosporine inhibit platelet-derived growth factor-stimulated vascular smooth muscle cell mitogenesis an investigation of mechanism Transplant Proc 30 1998 998 999
7. K. Wenke, B. Meiser, J. Thiery Simvastatin reduces graft vessel disease and mortality after heart transplantation a four-year randomized trial Circulation 96 1997 1398 1402
8. F. Akhlaghi, J. Ashley, A. Keogh, K. Brown Cyclosporine plasma unbound fraction in heart and lung transplantation recipients Ther Drug Monit 21 1999 8 16
9. D. Capone, P. Stanziale, A. Gentile, P. Imperatore, T. Pellegrino, V. Basile Effects of simvastatin and pravastatin on hyperlipidemia and cyclosporine blood levels in renal transplant recipients Am J Nephrol 19 1999 411 415
10. J.A. Kobashigawa, S. Katznelson, H. Laks Effect of pravastatin on outcomes after cardiac transplantation N Engl J Med 333 1995 621 627
11. A. Keogh, P. Macdonald, A. Kaan, C. Aboyoun, P. Spratt, J. Mundy Efficacy and safety of pravastatin vs. simvastatin after cardiac transplantation J Heart Lung Transplant 19 2000 529-7
12. G. Magnani, V. Carinci, C. Magelli, L. Potena, L.B. Reggiani, A. Branzi Role of statins in the management of dyslipidemia after cardiac transplant randomized controlled trial comparing the efficacy and the safety of atrovastatin with pravastatin J Heart Lung Transplant 19 2000 710 715
13. L.W. Miller, R.C. Schlant, J. Kobashigawa, S. Kubo, D.G. Renlund 24th Bethesda Conference: Cardiac transplantation. Task Force 5: complications J Am Coll Cardiol 22 1993 41 54
14. A.M. Keogh, H.A. Valantine, S.A. Hunt Impact of proximal or midvessel discrete coronary artery stenoses on survival after heart transplantation J Heart Lung Transplant 11 1992 892 901
15. D. Eich, J.A. Thompson, D.J. Ko Hypercholesterolemia in long-term survivors of heart transplantation an early marker of accelerated coronary artery disease J Heart Lung Transplant 10 1991 45 49
16. S.Z. Gao, J.S. Schroeder, S. Hunt, S.B. Stinson Retransplantation for severe accelerated coronary artery disease in heart transplant recipients Am J Cardiol 62 1988 876 881
17. B.M. Meiser, K. Wenke, J. Thiery Simvastatin decreases accelerated graft vessel disease after heart transplantation in an animal model Transplant Proc 25 1993 2077 2079
18. S. Katznelson, J.A. Kobashigawa Dual roles of HMG-CoA reductase inhibitors in solid organ transplantation lipid lowering and immunosuppression Kidney Int 52 Suppl 1995 S112 S115