Eradication of enteric helicobacters in Mongolian gerbils is complicated by the occurrence of Clostridium difficile enterotoxemia

Comparative Medicine

Volumn 55, Issue 3, 2005, Pages 265-268

  Bergin, Ingrid L ^a   Taylor, Nancy S ^a   Nambiar, Prashant R ^a   Fox, James G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; BISMUTH; METRONIDAZOLE; ANTIINFECTIVE AGENT;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; AUTOPSY; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; BIOCHEMISTRY; CECUM; CLOSTRIDIUM DIFFICILE; COLITIS; COLON; CONTROLLED STUDY; DIET; GERBIL; HELICOBACTER; HELICOBACTER INFECTION; HISTOPATHOLOGY; MORPHOLOGY; NONHUMAN; NUTRITION; POLYMERASE CHAIN REACTION; TOXEMIA; UNITED STATES; ANIMAL; ANIMAL DISEASE; BACTERIAL TRANSLOCATION; DRUG COMBINATION; DRUG EFFECT; INTESTINE; ISOLATION AND PURIFICATION; MICROBIOLOGY; OUTBRED STRAIN; PATHOGENICITY; PATHOLOGY; PSEUDOMEMBRANOUS COLITIS; RODENT DISEASE;

ANIMALS; ANIMALS, OUTBRED STRAINS; ANTI-BACTERIAL AGENTS; BACTERIAL TRANSLOCATION; CLOSTRIDIUM DIFFICILE; DRUG THERAPY, COMBINATION; ENTEROCOLITIS, PSEUDOMEMBRANOUS; GERBILLINAE; HELICOBACTER; HELICOBACTER INFECTIONS; INTESTINES; RODENT DISEASES;

EID: 24344437335     PISSN: 15320820     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Aldeen, W. E., M. Bingham, A. Aiderzada, J. Kucera, S. Jense, and K. C. Carroli. 2000. Comparison of the TOX A/B test to a cell culture cytotoxicity assay for the detection of Clostridium difficile in stools. Diagn. Microbiol. Infect. Dis. 36:211-213.
2. Bergin, I., N. Taylor, and J. Fox. 1999. Helicobacter pylori-induced gastritis in U.S.-bred Mongolian gerbils. Contemp. Top. Lab. Anim. Sci. 38(4):27.
3. Bergin, I. L., N. S. Taylor, and J. G. Fox. Unpublished data.
4. Foltz, C. J., J. G. Fox, L. Yan, and B. Shames. 1995. Evaluation of antibiotic therapies for eradication of Helicobacter hepaticus. Antimicrob. Agents Chemother. 39:1292-1294.
5. Foltz, C. J., J. G. Fox, L. Yan, and B. Shames. 1996. Evaluation of various oral antimicrobial formulations for eradication of Helicobacter hepaticus. Lab. Anim. Sci. 46:193-197.
6. Fox, J. G., F. E. Dewhirsi, Z. Shen, Y. Feng, N. S. Taylor, B. J. Paster, R. L. Ericson, C. N. Lau, P. Correa, J. C. Araya, and I. Roa. 1998. Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology 114:755-763.
7. Freeman, J. and M. H. Wilcox. 1999. Antibiotics and Clostridium difficile. Microbes Infect. 1:377-384.
8. Goto, K., H. Ohashi, A. Takakura, and T. Itoh. 2000. Current status of Helicobacter contamination of laboratory mice, rats, gerbils, and house musk shrews in Japan. Curr. Microbiol. 41:161-166.
9. Lowe, B. R., J. G. Fox, and J. G. Bartlett. 1980. Clostridium difficile-associated cecitis in guinea pigs exposed to penicillin. Am. J. Vet. Res. 41:1277-1279.
10. Lyerly, D. M., N. M. Sullivan, and T. D. Wilkins. 1983. Enzyme-linked immunosorbent assay for Clostridium difficile toxin A. J. Clin. Microbiol. 17:72-78.
11. Merrigan, M. M., S. P. Sambol, S. Johnson, and D. N. Gerding. 2003. Prevention of fatal Clostridium difficile-associated disease during continuous administration of clindamycin in hamsters. J. Infect. Dis. 188:1922-1927.
12. Naaber, P., R. H. Mikelsaar, S. Salminen, and M. Mikelsaar. 1998. Bacterial translocation, intestinal microflora and morphological changes of intestinal mucosa in experimental models of Clostridium difficile infection. J. Med. Microbiol. 47:591-598.
13. Nagahara, N., Y. Akiyama, M. Nakao, M. Tada, M. Kitano, and Y. Ogawa. 1998. Mucoadhesive microspheres containing amoxicillin for clearance of Helicobacter pylori. Antimicrob. Agents Chemother. 42:2492-2494.
14. Strittmatter, J. 1972. Elimination of Tyzzer's disease in the Mongolian gerbil (Meriones unguiculatus) by fostering to mice. Z. Versuchstierkd. 14:209-214. (In German.)
15. Taylor, N. S., G. M. Thorne, and J. G. Bartlett. 1981. Comparison of two toxins produced by Clostridium difficile. Infect. Immun. 34:1036-1043.
16. Whary, M. T. and J. G. Fox. 2004. Natural and experimental Helicobacter infections. Comp. Med. 54:128-158.