AT1 receptor in paraventricular nucleus mediates the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure

Autonomic Neuroscience: Basic and Clinical

Volumn 121, Issue 1-2, 2005, Pages 56-63

  Wang, Han Jun ^a   Zhang, Feng ^a   Zhang, Ying ^a   Gao, Xing Ya ^a   Wang, Wei ^b   Zhu, Guo Qing ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Angiotensin II; AT1 receptor; Cardiac sympathetic afferent reflex; Chronic heart failure; Paraventricular nucleus; Sympathetic nerve activity

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BRADYKININ; CAPTOPRIL; CHLORALOSE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LOSARTAN; URETHAN; ANTIHYPERTENSIVE AGENT; MESSENGER RNA;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DENERVATION; EPICARDIUM; HEART FAILURE; HEART RATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYMPATHETIC FUNCTION; THALAMUS MIDLINE NUCLEUS; VAGOTOMY; ANIMAL; ANTERIOR HYPOTHALAMUS; BIOSYNTHESIS; BLOOD PRESSURE; CHRONIC DISEASE; CONGESTIVE HEART FAILURE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; HEMODYNAMICS; MALE; METABOLISM; METHODOLOGY; NORTHERN BLOTTING; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REFLEX; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BLOTTING, NORTHERN; BLOTTING, WESTERN; BRADYKININ; CAPTOPRIL; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART FAILURE, CONGESTIVE; HEART RATE; HEMODYNAMIC PROCESSES; MALE; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ANGIOTENSIN, TYPE 1; REFLEX; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYMPATHETIC NERVOUS SYSTEM;

EID: 24344434546     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2005.07.003     Document Type: Article

References (35)

1. M. Bader, and D. Ganten It's renin in the brain: transgenic animals elucidate the brain renin angiotensin system Circ. Res. 90 2002 8
2. E. Badoer Hypothalamic paraventricular nucleus and cardiovascular regulation Clin. Exp. Pharmacol. Physiol. 28 2001 95
3. J.S. Bains, A. Potyok, and A.V. Ferguson Angiotensin II actions in paraventricular nucleus: functional evidence for neurotransmitter role in efferents originating in subfornical organ Brain Res. 599 1992 223
4. M.J. Cato, and G.M. Toney Angiotensin II excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: an in vitro patch-clamp study in brain slices J. Neurophysiol. 93 2005 403
5. J.N. Cohn, T.B. Levine, M.T. Olivari, V. Garberg, D. Lura, G.S. Francis, A.B. Simon, and T. Rector Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure N. Engl. J. Med. 311 1984 819
6. J.H. Coote Cardiovascular function of the paraventricular nucleus of the hypothalamus Biol. Signals 4 1995 142
7. J.H. Coote, Z. Yang, S. Pyner, and J. Deering Control of sympathetic outflows by the hypothalamic paraventricular nucleus Clin. Exp. Pharmacol. Physiol. 25 1998 461
8. D.W. Ferguson, W.J. Berg, and J.S. Sanders Clinical and hemodynamic correlates of sympathetic nerve activity in normal humans and patients with heart failure: evidence from direct microneurographic recordings J. Am. Coll. Cardiol. 16 1990 1125
9. Z.L. Guo, and A.R. Moazzami Involvement of nuclei in the hypothalamus in cardiac sympathoexcitatory reflexes in cats Brain Res. 1006 2004 36
10. N. Iwai, Y. Yamano, S. Chaki, F. Konishi, S. Bardhan, C. Tibbetts, K. Sasaki, M. Hasegawa, Y. Matsuda, and T. Inagami Rat angiotensin II receptor: cDNA sequence and regulation of the gene expression Biochem. Biophys. Res. Commun. 177 1991 299
11. D.P. Li, and H.L. Pan Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons J. Pharmacol. Exp. Ther. 2005
12. Y.F. Li, K.G. Cornish, and K.P. Patel Alteration of NMDA NR1 receptors within the paraventricular nucleus of hypothalamus in rats with heart failure Circ. Res. 93 2003 990
13. R. Ma, I.H. Zucker, and W. Wang Central gain of the cardiac sympathetic afferent reflex in dogs with heart failure Am. J. Physiol. 273 1997 H2664
14. R. Ma, H.D. Schultz, and W. Wang Chronic central infusion of Ang II potentiates cardiac sympathetic afferent reflex in dogs Am. J. Physiol. 277 1999 H15
15. R. Ma, G.Q. Zhu, and W. Wang Interaction of central Ang II and NO on the cardiac sympathetic afferent reflex in dogs Auton. Neurosci. 118 2005 51
16. A. Malliani, and M. Pagani The role of the sympathetic nervous system in congestive heart failure Eur. Heart J. 4 Suppl A 1983 49
17. M.J. McKinley, A.L. Albiston, A.M. Allen, M.L. Mathai, C.N. May, R.M. McAllen, B.J. Oldfield, F.A. Mendelsohn, and S.Y. Chai The brain renin-angiotensin system: location and physiological roles Int. J. Biochem. Cell Biol. 35 2003 901
18. G. Paxinos, and C. Watson The Rat Brain In Stereotaxic Coordinates Second Ed. 1986 Academic Press Inc Orlando
19. W. Wang, and R. Ma Cardiac sympathetic afferent reflexes in heart failure Heart Fail. Rev. 5 2000 57
20. W. Wang, and I.H. Zucker Cardiac sympathetic afferent reflex in dogs with congestive heart failure Am. J. Physiol., Regul. Integr. Comp. Physiol. 271 1996 R751
21. W. Wang, H.D. Schultz, and R. Ma Cardiac sympathetic afferent sensitivity is enhanced in heart failure Am. J. Physiol. 277 1999 H812
22. W. Wang, G.Q. Zhu, H.D. Schultz, and I.H. Zucker nNOS inhibition potentiates the central effects of angiotensin II on the cardiac sympathetic afferent reflex Circulation 102 2000 II-350
23. W. Wang, G.Q. Zhu, and I.H. Zucker Modulation of the cardiac sympathetic afferent reflex by nitric oxide in the paraventricular nucleus of dogs with chronic heart failure Circulation 104 2001 II739
24. A.M. Watson, R. Mogulkoc, R.M. McAllen, and C.N. May Stimulation of cardiac sympathetic nerve activity by central angiotensinergic mechanisms in conscious sheep Am. J. Physiol., Regul. Integr. Comp. Physiol. 286 2004 R1051
25. J.W. Wright, and J.W. Harding Brain angiotensin receptor subtypes in the control of physiological and behavioral responses Neurosci. Biobehav. Rev. 18 1994 21
26. M.R. Zahner, and H.L. Pan Role of paraventricular nucleus in the cardiogenic sympathetic reflex in rats Am. J. Physiol., Regul. Integr. Comp. Physiol. 288 2005 R420
27. G.Q. Zhu, K.P. Patel, I.H. Zucker, and W. Wang Microinjection of ANG II into paraventricular nucleus enhances cardiac sympathetic afferent reflex in rats Am. J. Physiol.: Heart Circ. Physiol. 282 2002 H2039
28. 1 receptors are involved in the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure Basic Res. Cardiol. 97 2002 320
29. 1 receptor mRNA antisense normalizes enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure Am. J. Physiol.: Heart Circ. Physiol. 287 2004 H1828
30. G.Q. Zhu, L. Gao, K.P. Patel, I.H. Zucker, and W. Wang Ang II in the paraventricular nucleus potentiates the cardiac sympathetic afferent reflex in rats with heart failure J. Appl. Physiol. 97 2004 1746
31. G.Q. Zhu, X.Y. Gao, F. Zhang, and W. Wang Reduced nitric oxide in the rostral ventrolateral medulla enhances cardiac sympathetic afferent reflex in rats with chronic heart failure Shengli XueBao 56 2004 47
32. I.H. Zucker Neural control of the circulation in heart failure and coronary ischaemia: introduction Clin. Exp. Pharmacol. Physiol. 23 1996 685
33. I.H. Zucker, and R.U. Pliquett Novel mechanisms of sympatho-excitation in chronic heart failure Heart Fail. Monit. 3 2002 2
34. I.H. Zucker, W. Wang, R.U. Pliquett, J.L. Liu, and K.P. Patel The regulation of sympathetic outflow in heart failure. The roles of angiotensin II, nitric oxide, and exercise training Ann. N. Y. Acad. Sci. 940 2001 431
35. I.H. Zucker, H.D. Schultz, Y.F. Li, Y. Wang, W. Wang, and K.P. Patel The origin of sympathetic outflow in heart failure: the roles of angiotensin II and nitric oxide Prog. Biophys. Mol. Biol. 84 2004 217