Dendritic cell neurofibroma with pseudorosettes lacks mutations in exons 1-15 of the neurofibromatosis type 2 gene

American Journal of Dermatopathology

Volumn 27, Issue 4, 2005, Pages 286-289

  Kazakov, Dmitry V ^a,c   Vanecek, Tomas ^a   Sima, Radek ^a   Kutzner, Heinz ^b   Michal, Michal ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b Dermatopathologische Gemeinschaftspraxis   (Germany)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Neurofibroma; Neurofibromatosis; Neuronevus; NF2 gene; Peripheral nerve sheath tumor

Indexed keywords

MERLIN;

ADULT; ARTICLE; CLINICAL ARTICLE; DENDRITIC CELL; DENDRITIC CELL NEUROFIBROMA WITH PSEUDOROSETTES; DNA EXTRACTION; EXON; FEMALE; GENE; GENE AMPLIFICATION; GENE FUNCTION; GENE MUTATION; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; NEUROFIBROMA; NEUROFIBROMATOSIS TYPE 2 GENE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PURIFICATION; TUMOR SUPPRESSOR GENE;

ADULT; DENDRITIC CELLS; DNA MUTATIONAL ANALYSIS; EXONS; FEMALE; GENES, NEUROFIBROMATOSIS 2; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; NEUROFIBROMA; POLYMERASE CHAIN REACTION;

EID: 24144476994     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.dad.0000157462.49463.b8     Document Type: Article

References (20)

1. Michal M, Fanburg-Smith JC, Mentzel T, et al. Dendritic cell neurofibroma with pseudorosettes: a report of 18 cases of a distinct and hitherto unrecognized neurofibroma variant. Am J Surg Pathol. 2001;25: 587-594.
2. Simpson RH, Seymour MJ. Dendritic cell neurofibroma with pseudorosettes: two tumors in a patient with evidence of neurofibromatosis. Am J Surg Pathol. 2001;25:1458-1459.
3. Trofatter JA, MacCollin MM, Rutter JL, et al. A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor. Cell. 1993;72:791-800.
4. Rouleau GA, Merel P, Lutchman M, et al. Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2. Nature. 1993;363:515-521.
5. Merel P, Hoang-Xuan K, Sanson M, et al. Screening for germ-line mutations in the NF2 gene. Genes Chromosomes Cancer. 1995;12:117-127.
6. Parry DM, MacCollin MM, Kaiser-Kupfer MI, et al. Germ-line mutations in the neurofibromatosis 2 gene: correlations with disease severity and retinal abnormalities. Am J Hum Genet. 1996;59:529-539.
7. Ruttledge MH, Andermann AA, Phelan CM, et al. Type of mutation in the neurofibromatosis type 2 gene (NF2) frequently determines severity of disease. Am J Hum Genet. 1996;59:331-342.
8. Ruttledge MH, Sarrazin J, Rangaratnam S, et al. Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas. Nat Genet. 1994;6:180-184.
9. Harada T, Irving RM, Xuereb JH, et al. Molecular genetic investigation of the neurofibromatosis type 2 tumor suppressor gene in sporadic meningioma. J Neurosurg. 1996;84:847-851.
10. Wellenreuther R, Kraus JA, Lenartz D, et al. Analysis of the neurofibromatosis 2 gene reveals molecular variants of meningioma. Am J Pathol. 1995;146:827-832.
11. Sciot R, Cin PD, Hagemeijer A, et al. Cutaneous sclerosing perineurioma with cryptic NF2 gene deletion. Am J Surg Pathol. 1999;23:849-853.
12. Lasota J, Fetsch JF, Wozniak A, et al. The neurofibromatosis type 2 gene is mutated in perineurial cell tumors; a molecular genetic study of eight cases. Am J Pathol. 2001;158:1223-1229.
13. Frank D, Gunawan B, Holtrup M, et al. Cytogenetic characterization of three malignant peripheral nerve sheath tumors. Cancer Genet Cytogenet. 2003;144:18-22.
14. Michal M, Kazakov DV, Belousova I, et al. A benign neoplasm with histopathological features of both schwannoma and retiform perineurioma (benign schwannoma-perineurioma): A report of six cases of a distinctive soft tissue tumor with a predilection for the fingers. Virchows Arch. 2004; 445:347-353.
15. Kazakov D, Pitha I, Sima R, et al. Hybrid peripheral nerve sheath tumors: schwannoma-perineurioma and neurofibroma-perineurioma. A report of three cases in extradigital locations. Ann Diagn Pathol. 2005;9:16-23.
16. Kazakov DV, Mukensnabl P, Zamecnik M, et al. Intraneural dendritic cell neurofibroma with pseudorosettes. Am J Dermatopathol. 2004;26: 72-75.
17. Kluwe L, Friedrich RE, Hagel C, et al. Mutations and allelic loss of the NF2 gene in neurofibromatosis 2-associated skin tumors. J Invest Dermatol 2000;114:1017-1021.
18. Zucman-Rossi J, Legoix P, Der Sarkissian H, et al. NF2 gene in neurofibromatosis type 2 patients. Hum Mol Genet. 1998;7:2095-2101.
19. Woodruff JM, Busam KJ. Histologically benign cutaneous dendritic cell tumor with pseudorosettes. Am J Surg Pathol. 2002;26:1644-1645; author reply 1645-1648.
20. Michal M, Fanburg-Smith JC, Mentzel T, et al. Histologically benign cutaneous dendritic cell tumor with pseudorosettes. Am J Surg Pathol. 2002;26:1645-1648.