Is central nitric oxide essential in hypertension?

Journal of Hypertension

Volumn 23, Issue 9, 2005, Pages 1637-1638

  Pointer, Mildred A ^a  

^a NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE;

EDITORIAL; HUMAN; HYPERTENSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASODILATATION;

EID: 24144476944     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.hjh.0000180352.99042.f3     Document Type: Editorial

References (15)

1. Li YF, Mayhan WG, Patel KP. NMDA-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide. Am J Physiol Heart Circ Physiol 2001; 281:H2328-H2336.
2. Kantzides A, Badoer E. nNOS-containing neurons in the hypothalamus and medulla project to the RVLM. Brain Res 2005; 1037:25-34.
3. Zhang K, Mayhan WG, Patel KP. Nitric oxide within the paraventricular nucleus mediates changes in renal sympathetic nerve activity. Am J Physiol 1997; 273:R864-R872.
4. MFR Ferrari, Fior-Chadi DR. Differential expression of NOS mRNA and protein in the nucleus tractus solitarii of young and aged Wistar Kyoto and spontaneously hypertensive rats. J Hypertens 2005; 23:1683-1690.
5. Sun MK, Hackett JT, Guyenet PG. Sympathoexcitatory neurons of rostral ventrolateral medulla exhibit pacemaker properties in the presence of a glutamate-receptor antagonist. Brain Res 1988; 438:23-40.
6. Guyenet PG, Haselton JR, Sun MK. Sympathoexcitatory neurons of the rostroventrolateral medulla and the origin of the sympathetic vasomotortone. Prog Brain Res 1989; 81:105-116.
7. Dampney RA, Polson JW, Potts PD, Hirooka Y, Horiuchi J. Functional organization of brain pathways subserving the baroreceptor reflex: studies in conscious animals using immediate early gene expression. Cell Mol Neurobiol 2003; 23:597-616.
8. DiCarlo SE, Zheng H, Collins HL, Rodenbaugh DW, Patel KP. Daily exercise normalizes the number of diaphorase (NOS) positive neurons in the hypothalamus of hypertensive rats. Brain Res 2002; 955:153-160.
9. Pontieri V, Venezuela MK, Scavone C, Michelini LC. Role of endogenous nitric oxide in the nucleus tratus solitarii on baroreflex control of heart rate in spontaneously hypertensive rats. J Hypertens 1998; 16:1993-1999.
10. Chan JY, Chan SH, Chang AY. Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat. Neuropharmacology 2004; 46:1184-1194.
11. Kimura Y, Hirooka Y, Sagara Y, Ito K, Kishi T, Shimokawa H, et al. Overexpression of Inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress. Circ Res 2005; 96:252-260.
12. Qadri F, Arens T, Schwarz EC, Hauser W, Dendorfer A, Dominiak P. Brain nitric oxide synthase activity in spontaneously hypertensive rats during the development of hypertension. J Hypertens 2003; 21:1687-1694.
13. Edwards MA, Arens T, Schwarz EC, Hauser W, Dendorfer A, Dominiak P. Unique levels of expression of N-methyl-D-aspartate receptor subunits and neuronal nitric oxide synthase in the rostral ventrolateral medulla of the spontaneously hypertensive rat. Brain Res Mol Brain Res 2004; 129: 33-43.
14. Chan JY, Wang LL, Chao YM, Chan SH. Downregulation of basal iNOS at the rostral ventrolateral medulla is innate in SHR. Hypertension 2003; 41:563-570.
15. Saito K, Ikeda M, Yoshioka H, Tomita T. Nitric oxide and effect of a radical scavenger N-tert-butyl-alpha-phenylnitrone on stroke in a rat model. Pharmacology 2005; 73:76-80.