Detection of nanobacteria-like particles in human atherosclerotic plaques

Acta Biologica Hungarica

Volumn 56, Issue 3-4, 2005, Pages 233-245

  Puskas L G ^a   Tiszlavicz, L ^b   Razga Zs ^b   Torday, L L ^b   Krenacs T ^b   Papp, J G Y ^a,b  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Aorta; Atherosclerosis; Carotid artery; Nanobacteria like particles; Vascular plaque

Indexed keywords

ASPARTIC ACID; HYDROXYAPATITE;

ADULT; AORTA; ARTERIOSCLEROSIS; ARTICLE; BACTERIUM; CALCINOSIS; CAROTID ARTERY; CHEMISTRY; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; MICROBIOLOGY; PARTICLE SIZE; PATHOGENICITY; PATHOLOGY; ULTRASTRUCTURE;

ADULT; AORTA; ARTERIOSCLEROSIS; ASPARTIC ACID; BACTERIA; CALCINOSIS; CAROTID ARTERIES; HUMANS; HYDROXYAPATITES; IMMUNOHISTOCHEMISTRY; PARTICLE SIZE;

EID: 24144464549     PISSN: 02365383     EISSN: None     Source Type: Journal    
DOI: 10.1556/ABiol.56.2005.3-4.7     Document Type: Article

References (47)

1. Sifil, A., Cavdar, C., Uretmen, P., Yavuzsen, T., Nazli, C., Camsari, T. (2000) Atherosclerotic heart disease in dialysis patients. Nephron 86, 387-388.
2. Kiechl, S., Egger, G., Mayr, M., Wiedermann, C. J., Bonora, E., Oberhollenzer, F., Muggeo, M., Xu, Q., Wick, G., Poewe, W., Willeit, J. (2001) Chronic infections and the risk of carotid atherosclerosis: Prospective results from a large population study. Circulation 103, 1064-1070.
3. Kessler, M. Atherosclerosis and hemodialysis. Nephrologie 21, 349-350.
4. Zoccali, C., Benedetto, F. A., Mallamaci, F., Tripepi, G., Fermo, I., Foca, A., Paroni, R., Malatoni, L. S. (2000) Inflammation is associated with carotid atherosclerosis in dialysis patients. Creed Investigators. Cardiovascular Risk Extended Evaluation in Dialysis Patients. J. Hypertens. 18, 1207-1213.
5. Lonnenmann, G. (2000) Chronic inflammation in hemodialysis: the role of contaminated dialysate. Blood Purif. 18, 214-223.
6. Zimmermann, J., Herrlinger, S., Pruy, A., Metzger, T., Wanner, C. (1999) Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 55, 648-658.
7. Lopes-Virella, M. F., Virella, G. (1985) Immunological and microbiological factors in the pathogenesis of atherosclerosis. Clin. Immunol. Immunopathol. 37, 377-386.
8. Bachmaier, K., Le, J., Penninger, J. M. (2000) Catching heart disease: antigenic mimicry and bacterial infections. Nat. Med 6, 841-842.
9. Burian, K., Kis, Z., Virok, D., Endresz, V., Prohaszka, Z., Duba, J., Berencsi, K., Boda, K., Horvath, L., Romics, L., Fust, G., Gonczol, E. (2001) Independent and joint effects of antibodies to human heat-shock protein 60 and Chlamydia pneumoniae infection in the development of coronary atherosclerosis. Circulation 103, 1503-1508.
10. Chiu, B. (1999) Multiple infections in carotid atherosclerotic plaques. Am. Heart. J. 138, S534-536.
11. Leionen, M., Saikku, P. (2000) Infections and atherosclerosis. Scand. Cardiovasc. J. 34, 12-20.
12. Ellis, R. W. (1997) Infection and coronary heart disease. J. Med. Microbiol. 46, 535-539.
13. Markus, H. S., Sitzer, M., Carrington, D., Mendall, M. A., Steinmetz, H. (1999) Chlamydia pneumoniae infection and early asymptomatic carotid atherosclerosis. Circulation 100, 832-837.
14. Stenvinkel, P., Heimburger, O., Jogestrand, T., Karnell, A., Samuelsson, A. (1999) Does persistent infection with Chlamydia pneumoniae increase the risk of atherosclerosis in chronic renal failure? Kidney Int. 55, 2531-2532.
15. Coles, K. A., Plant, A. J., Riley, T. V., Smith, D. W., McQuillan, B. M., Thompson, P. L. (1999) Lack of association between seropositivity to Chlamydia pneumoniae and carotid atherosclerosis. Am. J. Cardiol. 84, 825-828.
16. Gasbarrini, A., Cremonini, F., Armuzzi, A., Ojetti, V., Candelli, M., Di Campli, C., Sanz-Torre, E., Pola, R., Gasbarrini, G., Pola, P. (1999) The role of Helicobacter pylori in cardiovascular and cerebrovascular diseases. J. Physiol. Pharmacol. 50, 735-742.
17. Adam, E. (1987) High levels of cytomegalovirus antibody in patients requiring vascular surgery for atherosclerosis. Lancet 2, 291-293.
18. Horvath, R., Cerny, J., Benedik, J. Jr, Hokl, J., Jelinkova, I., Benedik, J. (2000) The possible role of human cytomegalovirus (HCMV) in the origin of atherosclerosis. J. Clin. Virol. 16, 17-24.
19. Chiu, B., Viira, E., Tucker, W., Fong, I. W. (1997) Chlamydia pneumoniae, cytomegalovirus, and herpes simplex virus in atherosclerosis of the carotid artery. Circulation 96, 2144-2148.
20. Mininck, C. R., Fabricant, C. G., Fabricant, J., Litrenta, M. M. (1979) Atheroarteriosclerosis induced by infection with a herpesvirus. Am. J. Pathol. 96, 673-706.
21. Wainwright, M. (1999) Nanobacteria and associated 'elementary bodies' in human disease and cancer. Microbiology 145, 2623-2624.
22. Wilson, P. W. F., Kauppila, L. I., O'Donnell, C. J., Kiel, D. P., Hannan, M., Polak, J. M., Cupples, A. (2001) Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortality. Circulation 103, 1529-1534.
23. Huang, H., Virmani, R., Younis, H., Burke, A. P., Kamm, R. D., Lee, R. T. (2001) The impact of calcification on the biomechanical stability of atherosclerotic plaques. Circulation 103, 1051-1056.
24. Shioi, A., Mori, K., Jono, S., Wakikawa, T., Hiura, Y., Koyama, H., Okuno, Y., Nishizawa, Y., Morii, H. (2000) Mechanism of atherosclerotic calcification. Z. Kardiol. 89 Suppl. 2, 75-79.
25. Shanahan, C. M., Proudfoot, D., Tyson, K. L., Cary, N. R., Edmonds, M., Weissberg, P. L. (2000) Expression of mineralisation-regulating proteins in association with human vascular calcification. Z. Kardiol. 89 Suppl. 2, 63-68.
26. Jeziorska, M., McCollum, C., Woolley, D. E. (1998) Calcification in atherosclerotic plaque of human carotid arteries: associations with mast cells and macrophages. J. Pathol. 185, 10-17.
27. Hsu, H. H., Tawfik, O., Sun, F. (2000) Effects of lectins on calcification by vesicles isolated from aortas of cholesterol-fed rabbits. Biochim. Biophys. Acta 1464, 262-272.
28. Kajander, E. O., Ciftcioglu, N. (1998) Nanobacteria: an alternative mechanism for pathogenic intra-and extracellular calcification and stone formation. Proc. Natl. Acad. Sci. USA 95, 8274-8279.
29. Kajander, E. O., Kuronen, I., Åkerman, K., Pelttari, A., Ciftcioglu, N. (1997) Nanobacteria from blood, the smallest culturable autonomously replicating agent on Earth. Proc. SPIE Int. Soc. Opt. Eng. 3111, 420-428.
30. Ciftcioglu, N., Bjorklund, M., Kuorikoski, K., Bergstrom, K., Kajander, E. O. (1999) Nanobacteria: an infectious cause for kidney stone formation. Kidney Int. 56, 1893-1898.
31. Hjelle, J. T., Miller-Hjelle, M. A., Poxton, I. R., Kajander, E. O., Ciftcioglu, N., Jones, M. L., Caughey, R. C., Brown, R., Millikin, P. D., Darras, F. S. (2000) Endotoxin and nanobacteria in polycystic kidney. Kidney Int. 57, 2360-2374.
32. Kajander, E. O., Ciftcioglu, N., Miller-Hjelle, M. A., Hjelle, J. T. (2001) Nanobacteria: controversial pathogens in nephrolithiasis and polycystic kidney disease. Curr. Opin. Nephrol. Hypertens. 10, 445-452.
33. Franklin, R. M., Martin, M. T. (1980) Staining and histochemistry of undecalcified bone embedded in a water-miscible plastic. Stain Technol. 55, 313-321.
34. Cisar, J. O., Xu, D. Q., Thompson, J., Swaim, W., Hu, L., Kopecko, D. J. (2000) An alternative interpretation of nanobacteria-induced biomineralization. Proc. Natl. Acad. Sci. USA 97, 11511-11515.
35. Ciftcioglu, N., Kajander, E. O. (1998) Interaction of nanobacteria with cultured mammalian cells. Pathophysiology 4, 259-270.
36. Ciftcioglu, N., Miller-Hjelle, M. A., Hjelle, J. T., Kajander, E. O. (2002) Inhibition of nanobacteria by antimicrobial drugs as measured by a modified microdilution method. Antimicrob. Agents Chemother. 46, 2077-2086.
37. Barr, S. C., Linke, R. A., Janssen, D., Guard, C. L., Smith, M. C., Daugherty, C. S., Scarlett, J. M. (2003) Detection of biofilm formation and nanobacteria under long-term cell culture conditions in serum samples of cattle, goats, cats, and dogs. Am. J. Vet. Res. 64, 176-182.
38. Kajander, E. O., Ciftcioglu, N., Aho, K., Garcia-Cuerpo, E. (2003) Characteristics of nanobacteria and their possible role in stone formation. Urol. Res. 31, 47-54.
39. Conte, V. A., Grases, F. F., Costa-Bauza, A., Piza, R. P. (2001) Microinfections and kidney lithiasis. Arch. Esp. Urol. 54, 855-860.
40. Li, Y., Wen, Y., Yang, Z., Wei, H., Liu, W., Tan, A., Wu, X., Wang, Q., Huang, S., Kajander, E. O., Ciftcioglu, N. (2002) Culture and identification of nanobacteria in bile. Zhonghua Yi Xue Za Zhi. 82, 1557-1560.
41. Morgan, M. B. (2002) Nanobacteria and calcinosis cutis. J. Cutan Pathol. 29, 173-175.
42. Drancourt, M., Jacomo, V., Lepidi, H., Lechevallier, E., Grisoni, V., Coulange, C., Ragni, E., Alasia, C., Dussol, B., Berland, Y., Raoult, D. (2003) Attempted isolation of Nanobacterium sp. microorganisms from upper urinary tract stones. J. Clin. Microbiol. 41, 368-372.
43. Price, P. A., Thomas, G. R., Pardini, A. W., Figueira, W. F., Caputo, J. M., Williamson, M. K. (2002) Discovery of a high molecular weight complex of calcium, phosphate, fetuin, and matrix gamma-carboxyglutamic acid protein in the serum of etidronate-treated rats. J. Biol. Chem. 277, 3926-3934.
44. Price, P. A., Lim, J. E. (2003) The inhibition of calcium phosphate precipitation by fetuin is accompanied by the formation of a fetuin-mineral complex. J. Biol. Chem. 278, 22144-22152.
45. Khullar, M., Sharma, S. K., Singh, S. K., Bajwa, P., Sheikh, F. A., Relan, V., Sharma, M. (2004) Morphological and immunological characteristics of nanobacteria from human renal stones of a north Indian population. Urol. Res. 32, 190-195.
46. Ciftcioglu, N., McKay, D. S., Kajander, E. O. (2003) Association between nanobacteria and periodontal disease. Circulation 108, 58-59.
47. Sedivy, R., Battistutti, W. B. (2003) Nanobacteria promote crystallization of psammoma bodies in ovarian cancer. APMIS 111, 951-4.