Deciphering the neural and molecular mechanisms of C. elegans behavior

Current Biology

Volumn 15, Issue 17, 2005, Pages

  Schafer, William R ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL BEHAVIOR; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; METABOLISM; NERVE CELL; NERVOUS SYSTEM FUNCTION; PHYSIOLOGY; REVIEW;

ANIMALS; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; MODELS, NEUROLOGICAL; NERVOUS SYSTEM PHYSIOLOGY; NEURONS;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 24044502527     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2005.08.020     Document Type: Review

References (59)

1. W.B. Wood The nematode Caenorhabditis elegans. 1998 Cold Spring Harbor Laboratory Cold Spring Harbor, New York
2. E.M. Hedgecock, J.G. Culotti, and D.H. Hall The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis of C. elegans Neuron 4 1990 61 85
3. C. Leung-Hagesteijn, A.M. Spence, B.D. Stern, Y. Zhou, M.W. Su, E.M. Hedgecock, and J.G. Culotti UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans Cell 71 1992 289 299
4. A. Alfonso, K. Grundahl, J.S. Duerr, H.-P. Han, and J.B. Rand The Caenorhabditis elegans unc-17 gene: a putative vesicular transporter Science 261 1993 617 619
5. D.G. Moerman, G.M. Benian, and R.H. Waterston Molecular cloning of the muscle gene unc-22 in Caenorhabditis elegans by Tc1 transposon tagging Proc. Natl. Acad. Sci. USA 83 1986 2579 2583
6. P. Sengupta, J.H. Chou, and C.I. Bargmann odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl Cell 84 1996 899 909
7. D. Levitan, and I. Greenwald Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene Nature 377 1995 351 354
8. S. Rajaram, M. Sedensky, and P.G. Morgan A stomatin homologue controls sensitivity to volatile anaesthetics in C. elegans Proc. Natl. Acad. Sci. USA 95 1998 8761 8766
9. L.E. Waggoner, K.A. Dickinson, D.S. Poole, Y. Tabuse, J. Miwa, and W.R. Schafer Long-term nicotine adaptation in Caenorhabditis elegans involves PKC-dependent changes in nicotinic receptor abundance J. Neurosci. 20 2000 8802 8811
10. J. White, E. Southgate, N. Thomson, and S. Brenner The structure of the Caenorhabditis elegans nervous system Philos. Trans. R. Soc. Lond. (Biol.) 314 1986 1 340
11. M. Chalfie, J.E. Sulston, J.G. White, J.N. Southgate, J.N. Thomson, and S. Brenner The neural circuit for touch sensitivity in C. elegans J. Neurosci. 5 1985 956 964
12. I. Mori, and Y. Ohshima Neural regulation of thermotaxis in Caenorhabditis elegans Nature 376 1995 344 348
13. J.M. Gray, J.J. Hill, and C.I. Bargmann A circuit for navigation in Caenorhabditis elegans Proc. Natl. Acad. Sci. USA 102 2005 3184 3191
14. P.J. Brockie, D.M. Madsen, Y. Zheng, J. Mellem, and V.A. Maricq Differential expression of glutamate receptor subunits in the nervous system of Caenorhabditis elegans and their regulation by the homeodomain protein UNC-42 J. Neurosci. 21 2001 1510 1522
15. G. Jansen, K.L. Thijssen, P. Werner, M. van der Horst, E. Hazendonk, and R.H. Plasterk The complete family of genes encoding G proteins of Caenorhabditis elegans Nat. Genet. 21 1999 414 419
16. E.L. Tsalik, T. Niacaris, A.S. Wenick, K. Pau, L. Avery, and O. Hobert LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system Dev. Biol. 263 2003 81 102
17. D. Dupuy, Q.R. Li, B. Deplancke, M. Boxem, T. Hao, P. Lamesch, R. Sequerra, S. Bosak, L. Doucette-Stamm, and I.A. Hope A first version of the Caenorhabditis elegans promoterome Genome Res. 14 2004 2169 2175
18. Y. Minakuchi, M. Ito, and Y. Kohara SPI: a tool for incorporating gene expression data into a four-dimensional database of Caenorhabditis elegans embryogenesis Bioinformatics 20 2004 1097 1109
19. Y. Zhang, C. Ma, T. Delohery, B. Nasipak, B. Foat, A. Bounoutas, H. Bussemaker, S. Kim, and M. Chalfie Identification of genes expressed in C. elegans touch receptor neurons Nature 418 2002 331 335
20. M. Colosimo, A. Brown, S. Mukhopadhyay, C. Gabel, A. Lanjuin, A. Samuel, and P. Sengupta Identification of thermosensory and olfactory neuron-specific genes via expression profiling of single neuron types Curr. Biol. 14 2004 2245 2251
21. H. Cinar, S. Keles, and Y. Jin Expression profiling of GABAergic motor neurons in Caenorhabditis elegans Curr. Biol. 15 2005 340 346
22. R.M. Fox, S.E. Von Stetina, S.J. Barlow, C. Shaffer, K.L. Olszewski, J.H. Moore, D. Dupuy, M. Vidal, and D.M. Miller A gene expression fingerprint of C. elegans embryonic motor neurons BMC Genomics 6 2005 42
23. H. Kunitomo, H. Uesugi, Y. Kohara, and Y. Iino Identification of ciliated sensory neuron-expressed genes in Caenorhabditis elegans using targeted pull-down of poly(A) tails Genome Biol. 6 2005 R17
24. M.B. Goodman, D.H. Hall, L. Avery, and S.R. Lockery Active currents regulate sensitivity and dynamic range in C. elegans neurons Neuron 20 1998 763 772
25. J.E. Mellem, P.J. Brockie, Y. Zheng, D.M. Madsen, and A.V. Maricq Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans Neuron 36 2002 933 944
26. R. O'Hagan, M. Chalfie, and M.B. Goodman The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals Nat. Neurosci. 8 2005 43 50
27. J.E. Richmond, and E.M. Jorgensen One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction Nat. Neurosci. 2 1999 1 7
28. C.M. Rogers, C.J. Franks, R.J. Walker, J.F. Burke, and L. Holden-Dye Regulation of the pharynx of Caenorhabditis elegans by 5-HT, octopamine, and FMRFamide-like neuropeptides J. Neurobiol. 49 2001 235 244
29. A. Miyawaki, J. Llopis, R. Heim, J.M. McCaffery, J.A. Adams, M. Ikura, and R.Y. Tsien Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin Nature 388 1997 882 887
30. J. Nakai, M. Ohkura, and K. Imoto A high signal-to-noise Ca(2+) probe composed of a single green fluorescent protein Nat. Biotechnol. 19 2001 137 141
31. R. Kerr, V. Lev-Ram, G. Baird, P. Vincent, R.Y. Tsien, and W.R. Schafer Optical imaging of calcium transients in C. elegans neurons and pharyngeal muscle Neuron 26 2000 583 594
32. H. Suzuki, R. Kerr, L. Bianchi, C. Frokjaer-Jensen, D. Slone, J. Xue, B. Gerstbrein, M. Driscoll, and W.R. Schafer In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation Neuron 39 2003 1005 1017
33. S.I. Shyn, R. Kerr, and W.R. Schafer Serotonin and Go modulate functional states of neurons and muscles controlling C. elegans egg-laying behavior Curr. Biol. 13 2003 1910 1915
34. M.A. Hilliard, A.J. Apicella, R. Kerr, H. Suzuki, P. Bazzicalupo, and W.R. Schafer In vivo imaging of C. elegans ASH neurons: cellular response and adaptation to chemical repellents EMBO J. 24 2005 1489
35. A.H. Kahn-Kirby, J.L. Dantzker, A.J. Apicella, W.R. Schafer, J. Browse, C.I. Bargmann, and J.L. Watts Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo Cell 119 2004 889 900
36. H.S. Fukuto, D.M. Ferkey, A.J. Apicella, H. Lans, T. Sharmeen, W. Chen, R.J. Lefkowitz, G. Jansen, W.R. Schafer, and A.C. Hart G protein-coupled receptor kinase function is essential for chemosensation in C. elegans Neuron 42 2004 581 593
37. K.D. Kimura, A. Miyawaki, K. Matsumoto, and I. Mori The C. elegans thermosensory neuron AFD responds to warming Curr. Biol. 14 2004 1291 1295
38. A.D. Samuel, R.A. Silva, and V.N. Murthy Synaptic activity of the AFD neuron in Caenorhabditis elegans correlates with thermotactic memory J. Neurosci. 23 2003 373 376
39. J.E. Sulston, and J.G. White Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans Dev. Biol. 78 1980 577 597
40. Y. Zheng, P.J. Brockie, J.E. Mellem, D.M. Madsen, and A.V. Maricq Neuronal control of locomotion in C. elegans is modified by a dominant mutation in the GLR-1 ionotropic glutamate receptor Neuron 24 1999 347 361
41. D. Weinshenker, A. Wei, L. Salkoff, and J.H. Thomas Block of an ether-a-go-go-like K(+) channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans J. Neurosci. 19 1999 9831 9840
42. J.C. Coates, and M. de Bono Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans Nature 419 2002 925 929
43. D. Tobin, D. Madsen, A. Kahn-Kirby, E. Peckol, G. Moulder, R. Barstead, A. Maricq, and C. Bargmann Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons Neuron 35 2002 307 318
44. J.T. Pierce-Shimomura, T.M. Morse, and S.R. Lockery The fundamental role of pirouettes in Caenorhabditis elegans chemotaxis J. Neurosci. 19 1999 9557 9569
45. E.L. Tsalik, and O. Hobert Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans J. Neurobiol. 56 2003 178 197
46. T. Wakabayashi, I. Kitagawa, and R. Shingai Neurons regulating the duration of forward locomotion in Caenorhabditis elegans Neurosci. Res. 50 2004 103 111
47. L. Waggoner, G.T. Zhou, R.W. Schafer, and W.R. Schafer Control of behavioral states by serotonin in Caenorhabditis elegans Neuron 21 1998 203 214
48. L.A. Hardaker, E. Singer, R. Kerr, G.-T. Zhou, and W.R. Schafer Serotonin modulates locomotory behavior and coordinates egg-laying and movement in Caenorhabditis elegans J. Neurobiol. 49 2001 304 311
49. T. Hills, P.J. Brockie, and A.V. Maricq Dopamine and glutamate control area-restricted search behavior in Caenorhabditis elegans J. Neurosci. 24 2004 1217 1225
50. M. de Bono, and C.I. Bargmann Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans Cell 94 2000 679 689
51. C.H. Rankin, C. Chiba, and C. Beck Caenorhabditis elegans: a new model system for the study of learning and memory Behav. Brain Res. 37 1990 89 92
52. S.R. Wicks, and C.H. Rankin Integration of mechanosensory stimuli in Caenorhabditis elegans J. Neurosci. 15 1995 2434 2444
53. A.C. Miller, T.R. Thiele, S. Faumont, M.L. Moravec, and S.R. Lockery Step-response analysis of chemotaxis in Caenorhabditis elegans J. Neurosci. 25 2005 3369 3378
54. H.A. Zariwala, A.C. Miller, S. Faumont, and S.R. Lockery Step response analysis of thermotaxis in Caenorhabditis elegans J. Neurosci. 23 2003 4369 4377
55. W.S. Ryu, and A.D. Samuel Thermotaxis in Caenorhabditis elegans analyzed by measuring responses to defined Thermal stimuli J. Neurosci. 22 2002 5727 5733
56. Z. Feng, C.J. Cronin, J.H. Wittig Jr., P.W. Sternberg, and W.R. Schafer An imaging system for standardized quantitative analysis of C. elegans behavior BMC Bioinformatics 5 2004 115
57. C.J. Cronin, J.E. Mendel, S. Mukhtar, Y.M. Kim, R.C. Stirbl, J. Bruck, and P.W. Sternberg An automated system for measuring parameters of nematode sinusoidal movement BMC Genet. 6 2005 5
58. W. Geng, P. Cosman, C.C. Berry, Z. Feng, and W.R. Schafer Automatic tracking, feature extraction and classification of C. elegans phenotypes IEEE Trans. Biomed. Eng. 51 2004 1811 1820
59. W. Geng, P. Cosman, J.H. Baek, C.C. Berry, and W.R. Schafer Quantitative classification and natural clustering of Caenorhabditis elegans behavioral phenotypes Genetics 165 2003 1117 1126