Internalization of trichosanthin via different endocytic mechanisms

Tsinghua Science and Technology

Volumn 10, Issue 4, 2005, Pages 430-434

  Zhang, Fan ^a   Sui, Senfang ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Cholesterol dependent endocytosis; Clathrin dependent endocytosis; Trichosanthin

Indexed keywords

BIOCHEMISTRY; CHOLESTEROL; HEALTH CARE; PLANTS (BOTANY);

CHOLESTEROL-DEPENDENT ENDOCYTOSIS; CLATHRIN-DEPENDENT ENDOCYTOSIS; TRICHOSANTHIN (TCS);

PROTEINS;

EID: 24044472739     PISSN: 10070214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1007-0214(05)70095-X     Document Type: Article

References (19)

1. Maraganore J M, Joseph M, Bailey M C. Purification and characterization of trichosanthin: Homology to the ricin A chain and implications as to mechanism of abortifacient activity. J. Biol. Chem., 1987, 262(24): 11628-11633.
2. Barbieri L, Battelli M G, Stirpe F. Ribosome-inactivating proteins from plants. Biochim. Biophys. Acta, 1993, 1154(3-4): 237-282.
3. Zhang X J, Wang J H. Homology of trichosanthin and ricin A chain. Nature, 1986, 321(6069): 477-478.
4. Collins E J, Robertus J D, LoPresti M, Stone K L, Williams K R, Wu P, Hwang K, Piatak M. Primary amino acid sequence of alpha-trichosanthin and molecular models for abrin A-chain and alpha-trichosanthin. J. Biol. Chem., 1990, 265(15): 8665-8669.
5. Shaw P C, Chan W L, Yeung H W, Ng T B. Minireview: Trichosanthin - a protein with multiple pharmacological properties. Life Sci., 1994, 55(4): 253-262.
6. Tsao S W, Yan K T, Yeung H W. Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii. Toxicon, 1986, 24(8): 831-840.
7. McGrath M S, Hwang K M, Caldwell S E, Gaston I, Luk K C, Wu P, Ng V L, Crowe S, Daniels J, Marsh J. GLQ223: An inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage. Proc. Natl. Acad. Sci. USA, 1989, 86(8): 2844-2848.
8. Chan W L, Shaw P C, Tam S C, Jacobsen C, Gliemann J, Nielsen M S. Trichosanthin interacts with and enters cells via LDL receptor family members. Biochem. Biophys. Res. Commun., 2000, 270(2): 453-457.
9. Xia X F, Sui S F. The membrane insertion of trichosanthin is membrane-surface-pH dependent. Biochem. J., 2000, 349(Pt 3): 835-841.
10. Larkin J M, Brown M S, Goldstein J L, Anderson R G. Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts. Cell, 1983, 33(1): 273-285.
11. Moya M, Dautry-Varsat A, Goud B, Louvard D, Boquet P. Inhibition of coated pit formation in Hep2 cells blocks the cytotoxicity of diphtheria toxin but not that of ricin toxin. J. Cell Biol., 1985, 101(2): 548-559.
12. Hansen S H, Sandvig K, van Deurs B. Clathrin and HA2 adaptors: Effects of potassium depletion, hypertonic medium, and cytosol acidification. J. Cell Biol., 1993, 121(1): 61-72.
13. Rothberg K G, Ying Y S, Kamen B A, Anderson R G. Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate. J. Cell Biol., 1990, 111(6): 2931-2938.
14. Rothberg K G, Heuser J E, Donzell W C, Ying Y S, Glenney J R, Anderson R G. Caveolin, a protein component of caveolae membrane coats. Cell, 1992, 68(4): 673-682.
15. Schnitzer J E, Oh P, Pinney E, Allard J. Filipin-sensitive caveolae-mediated transport in endothelium: Reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J. Cell Biol, 1994, 127(5): 1217-1232.
16. Subtil A, Dautry-Varsat A. Microtubule depolymerization inhibits clathrin coated-pit internalization in non-adherent cell lines while interleukin 2 endocytosis is not affected. J. Cell Sci., 1997, 110(Pt 19): 2441-2447.
17. Van Leuven F, Cassiman J J, Van Den Berghe H. Primary amines inhibit recycling of alpha 2M receptors in fibroblasts. Cell, 1980, 20(1): 37-43.
18. Axline S G, Reaven E P. Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. Role of subplasmalemmal micro-filaments. J. Cell Biol., 1974, 62(3): 647-659.
19. Painter R G, Whisenand I, McIntosh A T. Effects of cytochalasin B on actin and myosin association with particle binding sites in mouse macrophages: Implications with regard to the mechanism of action of the cytochalasins. J. Cell Biol., 1981, 91(2): 373-384.