The DBH -1021 C/T polymorphism is not associated with alcoholism but possibly with patients' exposure to life events

Journal of Neural Transmission

Volumn 112, Issue 9, 2005, Pages 1269-1274

  Freire, M T M V ^a   Hutz, M H ^a   Bau, C H D ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Alcoholism; Genetics; Hyperactivity; Life change

Indexed keywords

DOPAMINE BETA MONOOXYGENASE;

ALCOHOLISM; ALLELE; ARTICLE; BRAZIL; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; EUROPE; GENOTYPE; HETEROZYGOTE; HUMAN; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; PERSONALITY; PRIORITY JOURNAL; PROGENY;

ALCOHOLISM; BRAZIL; DOPAMINE BETA-HYDROXYLASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENOTYPE; HUMANS; LIFE CHANGE EVENTS; LINKAGE DISEQUILIBRIUM; PERSONALITY; POLYMORPHISM, GENETIC;

EID: 24044452899     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-005-0339-8     Document Type: Article

References (23)

1. American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders, 3rd edn. American Psychiatric Association, Washington, DC
2. J Biederman TE Wilens E Mick SV Faraone T Spencer 1998 Does attention-deficit hyperactive disorder impact the developmental course of drug and alcohol abuse and dependence? Biol Psychiatry 44 269 273
3. KK Bucholz R Cadoret CR Cloninger SH Dinwiddie VM Hesselbrock JI Nurnberger Jr T Reich I Schmidt MA Schuckit 1994 A new, semistructured psychiatric interview for use in genetic linkage studies: a report of the reliability of SSAGA. J Stud Alcohol 55 149 158
4. CR Cloninger 1987 A systematic method for clinical description and classification of personality variants. A proposal. Arch Gen Psychiatry 44 573 588
5. SP Craig VJ Buckle A Lamouroux J Mallet IW Craig 1988 Localization of the human dopamine beta hydroxylase (DBH) gene to chromosome 9q34. Cytogenet Cell Genet 48 48 50
6. JF Cubells DP van Kammen ME Kelley GM Anderson DT O'Connor LH Price R Malison PA Rao K Kobayashi T Nagatsu J Gelernter 1998 Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation. Hum Genet 102 533 540
7. JF Cubells HR Kranzler E McCance-Katz GM Anderson RT Malison LH Price J Gelernter 2000 A haplotype at the DBH locus, associated with low plasma dopamine β-hydroxylase ctivity, also associates with cocaine-induced paranoia. Mol Psychiatry 5 56 63
8. JF Cubells LH Price BS Meyers GM Anderson CP Zabetian GS Alexopoulos JC Nelson G Sanacora P Kirwin L Carpenter RT Malison J Gelernter 2002 Genotipe-controlled analysis of plasma dopamine β-hydroxylase activity in psychotic unipolar major depression. Biol Psychiatry 51 358 364
9. G Daly Z Hawi M Fitzgerald M Gill 1999 Mapping susceptibility loci in attention deficit hyperactivity disorder: preferential transmission of parental alleles at DAT1, DBH and DRD5 to affected children. Mol Psychiatry 4 192 196
10. JA Ewing 1984 Detecting alcoholism: the CAGE questionnaire. JAMA 252 1905 1907
11. KS Kendler M Neale R Kessler A Heath L Eaves 1993 A twin study of recent life events and difficulties. Arch Gen Psychiatry 50 789 796
12. KS Kendler RC Kessler EE Walters C MacLean MC Neale AC Heath LJ Eaves 1995 Stressful life events, genetic liability, and onset of episode of major depression in women. Am J Psychiatry 152 833 842
13. MD Kohnke CP Zabetian GM Anderson W Kolb I Gaertner G Buchkremer R Vonthein S Schick U Lutz AM Kohnke JF Cubells 2002 A genotype-controlled analysis of plasma dopamine β-hydroxylase in healthy and alcoholic subjects: evidence for alcohol-related differences in noradrenergic function. Biol Psychiatry 52 1151 1158
14. DK Lahiri JI Nurnberger 1991 A rapid non-enzimatic method for the preparation of HMW DNA from blood for RFLP studies. Nucl Acids Res 19 5444
15. GA Rogeness JW Maas MA Javors CA Macedo C Fischer WR Harris 1989 Attention deficit disorder symptoms and urine catecholamines. Psychiatry Res 27 241 251
16. T Roman M Schmitz GV Polanczyk M Eizirik LA Rohde MH Hutz 2002 Further evidence for the association between attention-deficit/hyperactivity disorder and the dopamine β-hydroxylase gene. Am J Med Genet 114 154 158
17. IG Sarason JH Johnson JM Siegel 1978 Assessing the impact of life changes: development of the Life Experiences Survey. J Consult Clin Psychol 46 932 946
18. R Tillman B Geller MJ Nickelsburg K Bolhofner JL Craney MP DelBello W Wigh 2003 Life events in a prepubertal and early adolescent bipolar disorder phenotype compared to attention-deficit hyperactive and normal controls. J Child Adolesc Psycopharmacol 13 243 251
19. J Wei H Xu CN Ramchand GP Hemmings 1997 Is the polymorphic microsatellite repeat of the dopamine β-hydroxylase gene associated with biochemical variability of the catecholamine pathway in schizophrenia? Biol Psychiatry 41 762 767
20. J Wei CN Ramchand GP Hemmings 1998 Taq I polymorphic sites at the human dopamine β-hydroxylase gene possibly associated with biochemical alterations of the cathecolamine pathway in schizophrenia. Psychiatr Genet 8 19 24
21. CP Zabetian GM Anderson SG Buxbaum RC Elston H Ichinose T Nagatsu KS Kim CH Kim RT Malison J Gelernter JF Cubells 2001 A quantitative-trait analysis of plasma-dopamine β-hydroxylase activity: evidence for a major functional polymorphism at the DBH Locus. Am J Hum Genet 68 515 522
22. HB Zhang YF Wang J Li B Wang L Yang 2004 Association of dopamine beta-hydroxylase polymorphism with attention deficit hyperactivity disorder in children. Beijing Da Xue Xue Bao 36 290 293
23. HB Zhang YF Wang J Li B Wang L Yang 2005 Association between dopamine beta hydroxylase gene and attention deficit hyperactivity disorder complicated with disruptive behavior disorder. Zhonghua Er Ke Za Zhi 43 26 30