Extracellular calcium deficiency and ryanodine inhibit Eimeria tenella sporozoite invasion in vitro

Parasitology Research

Volumn 97, Issue 1, 2005, Pages 59-62

  Schubert, Ulrike ^a   Fuchs, Jörg ^b   Zimmermann, Jana ^a   Jahn, Doreen ^a   Zoufal, Karen ^a  

^a Novoplant GmbH   (Germany)

^b LEIBNIZ INSTITUTE OF PLANT GENETICS AND CROP PLANT RESEARCH IPK   (Germany)

Author keywords

Apicomplexa; Calcium; Eimeria tenella; Invasion; Ryanodine

Indexed keywords

CALCIUM; CALCIUM CHANNEL; RYANODINE RECEPTOR;

ARTICLE; CALCIUM BINDING; CALCIUM DEFICIENCY; CALCIUM SIGNALING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EIMERIA TENELLA; EXTRACELLULAR CALCIUM; FLUORESCENCE ANALYSIS; HOST CELL; IN VITRO STUDY; INCUBATION TIME; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; SPOROZOITE;

ANIMALS; CALCIUM; EIMERIA TENELLA; MICROSCOPY, FLUORESCENCE; MICROSCOPY, PHASE-CONTRAST; RYANODINE; SPOROZOITES; STAINING AND LABELING;

APICOMPLEXA; EIMERIA TENELLA;

EID: 24044440130     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-005-1388-5     Document Type: Article

References (15)

1. Arrizabalaga G, Boothroyd JC (2004) Role of calcium during Toxoplasma gondii invasion and egress. Int J Parasitol 34:361-368
2. Augustine PC (1980) Effect of polyions, Ca++, and enzymes on penetration of cultured cells by Eimeria meleagrimitis sporozoites. J Parasitol 66:498-505
3. Bonhomme A, Bouchot A, Pezzella N, Gomez J, Le Moal H, Pinon JM (1999) Signalling during the invasion of host cells by Toxoplasma gondii. FEMS Microbiol Rev 23:551-561
4. Buck E, Zimanyi I, Abramson JJ, Pessah IN (1992) Ryanodine stabilizes multiple conformational states of the skeletal muscle calcium release channel. J Biol Chem 267:23560-23567
5. Carruthers VB, Sibley LD (1999) Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii. Mol Microbiol 31:421-428
6. Chapman HD (1998) Evaluation of the efficacy of anticoccidial drugs against Eimeria species in the fowl. Int J Parasitol 28:1141-1144
7. Hoff EF, Carruthers VB (2002) Is Toxoplasma egress the first step in invasion? Trends Parasitol 18:251-255
8. Hupe DJ, Pfefferkorn ER, Behrens ND, Peters K (1991) L-651,582 inhibition of intracellular parasitic protozoal growth correlates with host-cell directed effects. J Pharmacol Exp Ther 256:462-467
9. Lovett JL, Sibley LD (2003) Intracellular calcium stores in Toxoplasma gondii govern invasion of host cells. J Cell Sci 116:3009-3016
10. 2+ -dependence of conoid extrusion in Toxoplasma gondii tachyzoites. J Eukaryot Microbiol 43:120-127
11. Sutko JL, Airey JA, Welch W, Ruest L (1997) The pharmacology of ryanodine and related compounds. Pharmacol Rev 49:53-98
12. Vieira MC, Moreno SN (2000) Mobilization of intracellular calcium upon attachment of Toxoplasma gondii tachyzoites to human fibroblasts is required for invasion. Mol Biochem Parasitol 106:157-162
13. Wiersma HI, Galuska SE, Tomley FM, Sibley LD, Liberator PA, Donald RG (2004) A role for coccidian cGMP-dependent protein kinase in motility and invasion. Int J Parasitol 34:369-380
14. Williams RB (1994) Safety of the attenuated anticoccidial vaccine 'Paracox' in broiler chickens isolated from extraneous coccidial infection. Vet Res Commun 18:189-198
15. + channel/ryanodine receptor: modulation by endogenous effectors, drugs and disease states. Pharmacol Rev 49:1-51