Relationship between body composition changes and changes in physical function and metabolic risk factors in aging

Current Opinion in Clinical Nutrition and Metabolic Care

Volumn 8, Issue 5, 2005, Pages 523-528

  St Onge, Marie Pierre ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b Department of Nutrition Sciences   (United States)

Author keywords

Aging; Body composition; Metabolic risk; Physical function

Indexed keywords

AGING; ANTHROPOMETRY; BODY COMPOSITION; BODY FAT; BODY MASS; DUAL ENERGY X RAY ABSORPTIOMETRY; HUMAN; LEAN BODY WEIGHT; METABOLIC CAPACITY; MUSCLE ATROPHY; MUSCLE MASS; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL ACTIVITY; REVIEW; RISK FACTOR; SKELETAL MUSCLE;

ADIPOSE TISSUE; AGED; AGING; BODY COMPOSITION; BODY FAT DISTRIBUTION; ENERGY METABOLISM; HUMANS; MUSCLE, SKELETAL; RISK FACTORS;

EID: 23944523318     PISSN: 13631950     EISSN: 15353885     Source Type: Journal    
DOI: None     Document Type: Review

References (22)

1. Zamboni M, Zoico E, Scartezzini T, et al. Body composition changes in weight-stable elderly subjects: the effect of sex. Aging Clin Exp Res 2003; 15:321-327.
2. Heymsfield SB, Nunez C, Testolin C, Gallagher D. Anthropometry and methods of body composition measurement for research and field application in the elderly. Eur J Clin Nutr 2000; 54:326-832.
3. He Q, Heo M, Heshka S, et al. Total body potassium differs by sex and race across the adult age span. Am J Clin Nutr 2003; 78:72-77.
4. Cree MG, Newcomer BR, Katsanos CS, et al. Intramuscular and liver triglycerides are increased in the elderly. J Clin Endocrinol Metab 2004; 89:3864-3871. This is the only study to date to compare intramuscular and liver triglyceride content in young and elderly individuals. This study found increased triglycerides within muscle and liver of elderly compared to younger individuals and related them to increased metabolic risk.
5. Song M-Y, Ruts E, Kim J, et al. Sarcopenia and increased adipose tissue infiltration of muscle in elderly African American women. Am J Clin Nutr 2004; 79:874-880. This is the only longitudinal study to examine intramuscular adipose tissue in elderly women.
6. Stanforth PR, Jackson AS, Green AS, et al. Generalized abdominal visceral fat prediction models for black and white adults aged 17-65 y: the HERITAGE family study. Int J Obes 2004; 28:925-932.
7. Visser M, Pahor M, Tylavsky F, et al. One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women. J Appl Physiol 2003; 94:2368-2374.
8. Hughes VA, Roubenoff R, Wood M, et al. Anthropometric assessment of 10-y changes in body composition in the elderly. Am J Clin Nutr 2004; 80:475-482. Longitudinal study of longest follow-up to date to report body composition changes in elderly individuals.
9. Hughes VA, Frontera WR, Roubenoff R, et al. Longitudinal changes in body composition in older men and women: role of body weight change and physical activity. Am J Clin Nutr 2002; 76:473-481.
10. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 2002; 50:889-896.
11. Sternfeld B, Ngo L, Satarino WA, Tager IB. Associations of body composition with physical performance and self-reported functional limitation in elderly men and women. Am J Epidemiol 2002; 156:110-121.
12. Hughes VA, Frontera WR, Wood M, et al. Longitudinal muscle strength changes in older adults: influence of muscle mass, physical activity, and health. J Gerontol A Biol Sci Med Sci 2001; 56:B209-B217.
13. Goodpaster BH, Carlson CL, Visser M, et al. Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study. J Appl Physiol 2001; 90:2157-2165.
14. Visser M, Kritchevsky SB, Goodpaster BH, et al. Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70-79: the Health, Aging and Body Composition study. J Am Geriatr Soc 2002; 50:897-904.
15. Hernandez-Ono A, Monter-Carreola G, Zamora-Gonzalez J, et al. Association of visceral fat with coronary risk factors in a population-based sample of postmenopausal women. Int J Obes 2002; 26:33-39.
16. Pi-Sunyer FX. The epidemiology of central fat distribution in relation to disease. Nutr Rev 2004; 62:8120-8126. This is an excellent review of the importance of central fat distribution as a contributor to disease risk.
17. Petersen KF, Befroy D, Dufour S, et al. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 2003; 300:1140-1142.
18. Goodpaster BH, Krishnaswami S, Resnick H, et al. Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care 2003; 26:372-379.
19. Landers KA, Hunter GR, Wetzstein CJ, et al. The interrelationship among muscle mass, strength, and the ability to perform physical tasks of daily living in younger and older women. J Gerontol A Biol Sci Med Sci 2001; 56A:B443-B448.
20. St-Onge MP, Wang J, Shen W, et al. Dual-energy X-ray absorptiometry- measured lean soft tissue mass: differing relation to body cell mass across the adult life span. J Gerontol A Biol Sci Med Sci 2004; 59:796-800. This study shows that the proportion of lean tissue as active cell mass is lower as individuals get older and proposes an explanation for increased metabolic risk and physical limitation with age.
21. Littman AJ, Kristal AR, White E. Effects of physical activity intensity, frequency, and activity type on 10-y weight change in middle-aged men and women. Int J Obes 2005; 11 January [Epub ahead of print].
22. Havenam-Nies A, de Groot LC, van Staveren WA. Dietary quality, lifestyle factors and healthy ageing in Europe: the SENECA study. Age Ageing 2003; 32:427-434.