A wide range of protein isoforms in serum and plasma uncovered by a quantitative intact protein analysis system

Proteomics

Volumn 5, Issue 13, 2005, Pages 3343-3352

  Misek, David E ^a   Kuick, Rork ^a   Wang, Hong ^a,d   Galchev, Vladimir ^a   Deng, Bin ^a,d   Zhao, Rong ^a   Tra, John ^a   Pisano, Michael R ^c   Amunugama, Ravi ^c   Allen, David ^c   Walker, Angela K ^a   Strahler, John R ^a   Andrews, Philip ^a   Omenn, Gilbert S ^b   Hanash, Samir M ^a,d  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c PRS Proteomics   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Biomarkers; Plasma; Protein isoforms; Proteome profiling; Serum

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 ANTIPLASMIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; ANGIOTENSINOGEN; ANTITHROMBIN III; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN A4; APOLIPOPROTEIN C3; BIOLOGICAL MARKER; CERULOPLASMIN; CITRIC ACID; CLUSTERIN; COMPLEMENT COMPONENT C3; EDETIC ACID; FIBRINOGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; HAPTOGLOBIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; ISOPROTEIN; KININOGEN; OROSOMUCOID; PLASMA PROTEIN; PREALBUMIN; SERUM AMYLOID P; TRANSFERRIN; UNINDEXED DRUG; VITRONECTIN;

AMINO ACID SEQUENCE; ANTICOAGULATION; ARTICLE; CAUCASIAN; CONTROLLED STUDY; HUMAN; HYDROPHOBICITY; IMAGE ANALYSIS; INTACT PROTEIN ANALYSIS SYSTEM; ISOELECTRIC FOCUSING; LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PLASMA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SERUM; TANDEM MASS SPECTROMETRY;

ANTICOAGULANTS; BIOLOGICAL MARKERS; BLOOD PROTEINS; CARBOCYANINES; CHROMATOGRAPHY; CHROMATOGRAPHY, LIQUID; EDETIC ACID; FLUORESCENT DYES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MASS SPECTROMETRY; MOLECULAR WEIGHT; PROTEIN ISOFORMS; PROTEOME; PROTEOMICS;

EID: 23944517301     PISSN: 16159853     EISSN: None     Source Type: Journal    
DOI: 10.1002/pmic.200500103     Document Type: Article

References (17)

1. Hanash, S., Nature 2003, 422, 226-232.
2. Wang, H., Hanash, S., Mass Spectrom. Rev. 2005, 24, 413-426.
3. Pedersen, S. K., Harry, J. L., Sebastian, L., Baker, J., Traini, M. D., McCarthy, J. T., Manoharan, A. et al., J. Proteome Res. 2003, 2, 303-311.
4. Zuo, X., Speicher, D. W., Proteomics 2002, 2, 58-68.
5. Washburn, M. P., Wolters, D., Yates, J. R., 3rd, Nat. Biotechnol. 2001, 19, 242-247.
6. Pieper, R., Su, Q., Gatlin, C. L., Huang, S. T., Anderson, N. L., Steiner, S., Proteomics 2003, 3, 422-432.
7. Wang, H., Clouthier, S. G., Galchev, V., Misek, D. E., Duffner, U., Min, C.-K., Zhao, R. et al., Mol. Cell. Proteomics 2005, 4, 618-625.
8. Omenn, G. S., Proteomics 2004, 4, 1235-1240.
9. de Bruijn, M. H., Fey, G. H., Proc. Natl. Acad. Sci. USA 1985, 82, 708-712.
10. Fong, K. Y., Botto, M., Walport, M. J., So, A. K., Genomics 1990, 7, 579-586.
11. Rosenberg, M. E., Silkensen, J., Int. J. Biochem. Cell. Biol. 1995, 27, 633-645.
12. Underwood, P. A., Kirkpatrick, A., Mitchell, S. M., Biochem. J. 2002, 365, 57-67.
13. Hwang, S. R., Steineckert, B., Kohn, A., Palkovits, M., Hook, V. Y., J. Biol. Chem. 1999, 274, 1821-1827.
14. Marshall, J., Kupchak, P., Zhu, W., Yantha, J., Vrees, T., Furesz, S., Jacks, K. et al., J. Proteome Res. 2003, 2, 361-372.
15. Zhang, Z., Bast, R. C., Jr., Yu, Y., Li, J., Sokoll, L. J., Rai, A. J., Rosenzweig, J. M. et al., Cancer Res. 2004, 64, 5882-5890.
16. He, Q. Y., Lau, G. K., Zhou, Y., Yuen, S. T., Lin, M. C., Kung, H. F., Chiu, J. F., Proteomics 2003, 3, 666-674.
17. Zhang, R., Barker, L., Pinchev, D., Marshall, J., Rasamoelisolo, M., Smith, C., Kupchak, P. et al., Proteomics 2004, 4, 244-256.