2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT 6 receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 19, 2005, Pages 4230-4234

  Mattsson, Cecilia ^a   Sonesson, Clas ^a   Sandahl, Anna ^a   Greiner, Hartmut E ^b   Gassen, Michael ^b   Plaschke, Jörg ^b   Leibrock, Joachim ^b   Böttcher, Henning ^b  

^a Carlsson Research AB   (Sweden)

^b MERCK KGAA   (Germany)

Author keywords

3 (1,2,3,6 Tetrahydropyridin 4 yl) 1H indole; 5 HT6; 5 Hydroxytryptamine6 agonist

Indexed keywords

5 CHLORO 2 METHYL 3 (1,2,3,6 TETRAHYDROPYRIDIN 4 YL) 1H INDOLE; 5 METHOXY 3 (1,2,3,6 TETRAHYDRO 4 PYRIDYL) 1H INDOLE; CYCLIC AMP; INDOLE DERIVATIVE; LYSERGIDE; SEROTONIN 6 RECEPTOR; SEROTONIN AGONIST; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; IC 50; STRUCTURE ACTIVITY RELATION;

CELL LINE; CYCLIC AMP; HUMANS; INDOLES; RADIOLIGAND ASSAY; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 23944514825     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.06.067     Document Type: Article

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