Aciclovir induced posterior leucoencephalopathy [5]

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 76, Issue 9, 2005, Pages 1308-1309

  Mahad, Don ^a   Jarvis, J ^a   Chinnery, P F ^a   Mitra, D ^a   Gholkar, A ^a   Hellden A ^b  

^a NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; METHYLPREDNISOLONE; NEUROTOXIN;

ADULT; ANAMNESIS; CASE REPORT; CEREBROSPINAL FLUID; CLINICAL FEATURE; DRUG EFFICACY; ELECTROENCEPHALOGRAM; FEMALE; HERPES SIMPLEX ENCEPHALITIS; HERPES ZOSTER; HUMAN; KIDNEY FAILURE; LABORATORY TEST; LETTER; LEUKOENCEPHALOPATHY; NEUROTOXICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; OPHTHALMOSCOPY; PERITONEAL DIALYSIS; PRIORITY JOURNAL;

EID: 23944507723     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.2004.059824     Document Type: Letter

References (5)

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2. Rashiq S, Briewa L, Mooney M, et al. Distinguishing acyclovir neurotoxicity from encephalomyelitis. J Intern Med 1993;234:507-11.
3. Braun JS, Apel I, Schaffer S, et al. Delirium during oral therapy of herpes zoster with acyclovir: case report and brief review of central nervous system side-effects of acyclovir. Nervenarzt 1998;69:1015-18.
4. Hellden A, Odar-Cederlof I, Diener P, et al. High serum concentrations of the acyclovir main metabolite 9-carboxymethoxymethylguanine in renal failure patients with acyclovir-related neuropsychiatric side effects: an observational study. Nephrol Dial Transplant 2003;18:1135-41.
5. Cohen SM, Minkove JA, Zebley JW, et al. Severe but reversible neurotoxicity from acyclovir. Ann Intern Med 1984;100:920.