Neural and metabolic mechanisms of excessive muscle fatigue in maintenance hemodialysis patients

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 3 58-3, 2005, Pages

  Johansen, Kirsten L ^a,b   Doyle, Julie ^c   Sakkas, Giorgos K ^b   Kent Braun, Jane A ^d  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NORTHERN CALIFORNIA INSTITUTE FOR RESEARCH AND EDUCATION   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

31P magnetic resonance spectroscopy; Central fatigue; Electromyography; Muscle activation; Oxidative phosphorylation

Indexed keywords

CREATINE PHOSPHATE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COMORBIDITY; DIALYSIS; ELECTROMYOGRAPHY; EXERCISE; FEMALE; HEMODIALYSIS; HUMAN; LEG EXERCISE; MALE; METABOLIC PARAMETERS; MUSCLE ACTION POTENTIAL; MUSCLE FATIGUE; MUSCLE FORCE; MUSCLE METABOLISM; OXIDATIVE PHOSPHORYLATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SKELETAL MUSCLE;

ANKLE; CASE-CONTROL STUDIES; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; ISOMETRIC CONTRACTION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; MUSCLE FATIGUE; MUSCLE, SKELETAL; NERVOUS SYSTEM; RENAL DIALYSIS;

EID: 23944486587     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00187.2005     Document Type: Article

References (56)

1. Akiba T, Matsui N, Shinohara S, Fujiwara H, Nomura T, and Marumo F. Effects of recombinant human erythropoietin and exercise training on exercise capacity in hemodialysis patients. Artif Organs 19: 1262-1268, 1995.
2. Allman B and Rice C. Neuromuscular fatigue and aging: central and peripheral factors. Muscle Nerve 25: 785-796, 2002.
3. Bigland-Ritchie B, Dawson N, Johansson R, and Lippold O. Reflex origin for the slowing of motoneurone firing rates in fatigue of human voluntary contractions. J Physiol 379: 451-459, 1986.
4. Bigland-Ritchie B, Furbush F, and Woods J. Fatigue of intermittent submaximal voluntary contractions: central and peripheral factors. J Appl Physiol 61: 421-429, 1986.
5. Bilodeau M, Henderson T, Nolta B, Pursley P, and Sandfort G. Effect of aging on fatigue characteristics of elbow flexor muscles during sustained submaximal contraction. J Appl Physiol 91: 2654-2664, 2001.
6. Bradley J, Anderson J, Evans D, and Cowley A. Impaired nutritive skeletal muscle blood flow in patients with chronic renal failure. Clin Sci (Lond) 79: 239-245, 1990.
7. Brown T, Stoyanova R, Greenberg T, Srinivasan T, and Murphy-Boesch J. NOE enhancements and T1 relaxation times of phosphorylated metabolites in human calf muscle at 15 Tesla. Magn Reson Med 33: 417-421, 1995.
8. Cavanagh P, Mulfinger L, and Owens D. How do the elderly negotiate stairs? Muscle Nerve Suppl 5: S52-S55, 1996.
9. Chance B, Leigh J, Clark B, Maris J, Kent J, Nioka S, and Smith D. Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function. Proc Natl Acad Sci USA 82: 8384-8388, 1985.
10. Cooke R, Franks K, Luciani G, and Pate E. The inhibition of rabbit skeletal muscle contraction by hydrogen ions and phosphate. J Physiol 395: 77-97, 1988.
11. Diesel W, Knight B, Noakes T, Swanepoel C, Smit R, Kaschula R, and Sinclair-Smith C. Morphologic features of the myopathy associated with chronic renal failure. Am J Kidney Dis 22: 677-684, 1993.
12. Diesel W, Voakes T, Swanepoel C, and Lambert M. Isokinetic muscle strength predicts maximum exercise tolerance in renal patients on chronic hemodialysis. Am J Kidney Dis 16: 109-114, 1990.
13. 31P NMR spectroscopy investigation of muscle metabolism in hemodialysis patients. Kidney Int 43: 885-892, 1993.
14. Edwards R, Hill D, Jones D, and Merton P. Fatigue of long duration in human skeletal muscle after exercise. J Physiol 272: 769-778, 1977.
15. Fahal I, Ahmad R, and Edwards R. Muscle weakness in continuous ambulatory peritoneal dialysis patients. Perit Dial Int 16: S419-S423, 1996.
16. Fahal I, Bell G, Bone J, and Edwards R. Physiological abnormalities of skeletal muscle in dialysis patients. Nephrol Dial Transplant 12: 119-127, 1997.
17. Fitts R. Cellular mechanisms of muscle fatigue. Physiol Rev 74: 49-94, 1994.
18. Glatter K, Graves S, Hollenberg N, Soszynski P, Tao Q, Frem G, Williams G, and Lazarus J. Sustained volume expansion and [Na,K]-ATPase inhibition in chronic renal failure. Am J Hypertens 7: 1016-1025, 1994.
19. Grunze M, Kohlmann M, Mulligan M, Gruner I, Koeppel M, and Bommer J. Mechanisms of improved physical performance of chronic hemodialysis patients after erythropoietin treatment. Am J Nephrol 10: 15-23, 1990.
20. Hunter S and Enoka R. Sex differences in the fatigability of arm muscles depends on absolute force during isometric contractions. J Appl Physiol 91: 2686-2694, 2001.
21. Johansen K, Chertow G, Ng A, Mulligan K, Carey S, Schoenfeld P, and Kent-Braun J. Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney Int 57: 2564-2570, 2000.
22. Johansen K, Shubert T, Doyle J, Soher B, Sakkas G, and Kent-Braun J. Muscle atrophy in patients receiving hemodialysis: effects on muscle strength, muscle quality, and physical function. Kidney Int 63: 201-207, 2003.
23. Kemp G, Crowe A, Anijeet H, Gong Q, Bimson W, Frostick S, Bone J, Bell G, and Roberts J. Abnormal mitochondrial function and muscle wasting, but normal contractile efficiency, in haemodialysed patients studied non-invasively in vivo. Nephrol Dial Transplant 19: 1520-1527, 2004.
24. Kent-Braun J. Central and peripheral contributions to muscle fatigue in humans during sustained maximal effort. Eur J Appl Physiol Occup Physiol 80: 57-63, 1999.
25. Kent-Braun J and LeBlanc R. Quantitation of central activation failure during maximal voluntary contractions in humans. Muscle Nerve 19: 861-869, 1996.
26. Kent-Braun J, Miller R, and Weiner M. Human skeletal muscle metabolism in health and disease: utility of magnetic resonance spectroscopy. Exerc Sport Sci Rev 23: 305-347, 1995.
27. Kent-Braun J, Miller R, and Weiner M. Phases of metabolism during progressive exercise to fatigue in human skeletal muscle. J Appl Physiol 75: 573-580, 1993.
28. Kent-Braun J and Ng A. Specific strength and voluntary muscle activation in young and elderly women and men. J Appl Physiol 87: 22-29, 1999.
29. Kent-Braun J, Ng A, Doyle J, and Towse T. Human skeletal muscle responses vary with age and gender during fatigue due to incremental isometric exercise. J Appl Physiol 93: 1813-1823, 2002.
30. Kent-Braun J, Sharma K, Weiner M, and Miller R. Effects of exercise on muscle activation and metabolism in multiple sclerosis. Muscle Nerve 17: 1162-1169, 1994.
31. Kouidi E, Albani M, Natsis K, Megalopoulos A, Gigis P, Guiba-Tziampiri O, Tourkantonis A, and Deligiannis A. The effects of exercise training on muscle atrophy in haemodialysis patients. Nephrol Dial Transplant 13; 685-699, 1998.
32. Lundin A, Stein R, Brown C, LaBelle P, Kaiman F, Delano B, Heneghan W, Lazarus N, Krasnow N, and Friedman E. Fatigue, acid-base and electrolyte changes with exhaustive treadmill exercise in hemodialysis patients. Nephron 46: 57-62, 1987.
33. MacDougall I, Lewis N, Saunders M, Cochlin D, Davies M, Hutton R, Fox K, Coles G, and Williams J. Long-term cardiorespiratory effects of amelioration of renal anaemia by erythropoietin. Lancet 335: 489-493, 1990.
34. Mancini D, Walter G, Reichek N, Lenkinski R, McCully K, Mullen J, and Wilson J. Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation 85: 1364-1373, 1992.
35. Marrades R, Alonso J, Roca J, Gonzalez de Suso J, Campistol J, Barbera J, Diaz O, Torregrosa J, Mascians J, Rodriguez-Roisin R, and Wagner P. Cellular bioenergetics after erythropoietin therapy in chronic renal failure. J Clin Invest 97: 2101-2110, 1996.
36. 2 transport during exercise in patients with chronic renal failure. J Clin Invest 97: 2092-2100, 1996.
37. McDermott M, Greenland P, Liu K, Guralnik J, Criqui M, Dolan N, Chan C, Celic L, Pearce W, Schneider J, Sharma L, Clark E, Gibson D, and Martin G. Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment. JAMA 286: 1599-1606, 2001.
38. McDermott M, Kerwin D, Liu K, Martin G, O'Brien E, Kaplan H, and Greenland P. Prevalence and significance of unrecognized lower extremity peripheral arterial disease in general medicine practice. J Gen Intern Med 16: 384-390, 2001.
39. 31P-Magnetic resonance spectroscopy assessment of subnormal oxidative metabolism in skeletal muscle of renal failure patients. J Clin Invest 91: 420-424, 1993.
40. Moore G, Parsons D, Stray-Gundersen J, Painter P, Brinker K, and Mitchell J. Uremic myopathy limits aerobic capacity in hemodialysis patients. Am J Kidney Dis 22: 277-287, 1993.
41. Narici M, Bordini M, and Cerretelli P. Effect of aging on human adductor pollicis muscle function. J Appl Physiol 71: 1277-1281, 1991.
42. National Kidney Foundation Kidney Disease Outcomes Quality Initiative Advisory Board. NKF-K/DOQI Clinical Practice Guidelines for anemia of chronic kidney disease: update 2000. Am J Kidney Dis 37: S182-S238, 2001.
43. National Kidney Foundation Kidney Disease Outcomes Quality Initiative Advisory Board. NKF-K/DOQ1 Clinical Practice Guidelines for hemodialysis adequacy: update 2000. Am J Kidney Dis 37: S7-S64, 2001.
44. Nosek T, Fender K, and Godt R. It is diprotonated inorganic phosphate that depresses force in skinned skeletal muscle fibers. Science 236: 191-193, 1987.
45. Robertson H, Haley N, Guthrie M, Cardenas D, Eschbach J, and Adamson J. Recombinant erythropoietin improves exercise capacity in anemic hemodialysis patients. Am J Kidney Dis 15: 325-332, 1990.
46. Russ D and Kent-Braun J. Sex differences in human skeletal muscle fatigue are eliminated under ischemic conditions. J Appl Physiol 94: 2414-2422, 2003.
47. Sakkas G, Ball D, Mercer T, Sargeant A, Tolfrey K, and Naish P. Atrophy of non-locomotor muscle in patients with end-stage renal failure. Nephrol Dial Transplant 18: 2074-2081, 2003.
48. + regulation contributes to exercise limitation in end-stage renal failure. Kidney Int 63: 283-290, 2003.
49. Sharma K, Kent-Braun J, Majumdar S, Huang Y, Mynhier M, Weiner M, and Miller R. Physiology of fatigue in amyotrophic lateral sclerosis. Neurology 45: 733-740, 1995.
50. Sharma K, Kent-Braun J, Mynhier M, Weiner M, and Miller R. Excessive muscular fatigue in the postpoliomyelitis syndrome. Neurology 44: 642-646, 1994.
51. +-ATPaSe inhibitor which circulates in renal failure but not in essential hypertension. Prog Biochem Pharmacol 23: 46-54, 1988.
52. Taylor D, Styles P, Matthews P, Arnold D, Gadian D, Bore P, and Radda G. Energetics of human muscle: exercise-induced ATP depletion. Magn Reson Med 3: 44-54, 1986.
53. Thompson C, Kemp G, Barnes P, Rajagopalan B, Styles P, Taylor D, and Radda G. Uraemic muscle metabolism at rest and during exercise. Nephrol Dial Transplant 9: 1600-1605, 1994.
54. Thompson C, Kemp G, Taylor D, Ledingham J, Radda G, and Rajagopalan B. Effect of chronic uraemia on skeletal muscle metabolism in man. Nephrol Dial Transplant 8: 218-222, 1993.
55. 31P-NMR study. J Appl Physiol 64: 2333-2339, 1988.
56. Wolfson L, Judge J, Whipple R, and King M. Strength is a major factor in balance, gait, and the occurrence of falls. J Gerontol A Biol Sci Med Sci 50: 64-67, 1995.