Hypocholesterolemic effect of physically refined rice bran oil: Studies of cholesterol metabolism and early atherosclerosis in hypercholesterolemic hamsters

Journal of Nutritional Biochemistry

Volumn 16, Issue 9, 2005, Pages 521-529

  Ausman, Lynne M ^a,b   Rong, Ni ^a,b   Nicolosi, Robert J ^c  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY   (United States)

^c UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Absorption; Bile acids; Cholesterol; Fatty streak area; HMG CoA reductase activity; Neutral sterols; Rice bran oil

Indexed keywords

BILE ACID; CHOLESTEROL; COCONUT OIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; RICE BRAN OIL; STEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; COCONUT; CONTROLLED STUDY; DIET; ENZYME ACTIVITY; HAMSTER; HYPERCHOLESTEROLEMIA; MALE; NONHUMAN; RAPESEED;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AORTA; ARTERIOSCLEROSIS; BILE ACIDS AND SALTS; BODY WEIGHT; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CRICETINAE; FECES; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYPERCHOLESTEROLEMIA; INTESTINES; LIVER; MACROPHAGES; MALE; MESOCRICETUS; PLANT OILS; STEROLS;

ANIMALIA; BRASSICA NAPUS VAR. NAPUS; COCO; CRICETINAE; PRIMATES; RODENTIA; SINAPIS ARVENSIS;

EID: 23944482463     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2005.01.012     Document Type: Article

References (65)

1. The Expert Panel Report of the National Cholesterol Education Program Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults: NHLBI Arch Intern Med 148 1988 36 69
2. D.M. Hegsted, R.B. McGandy, M.L. Myers, and F.J. Stare Quantitative effects of dietary fat on serum cholesterol in man Am J Clin Nutr 17 1965 281 295
3. A. Keys, J.T. Anderson, and F. Grande Prediction of serum-cholesterol responses of man to changes in fats in the diet Lancet 2 1957 959 966
4. F.H. Mattson, and S.M. Grundy Prediction of serum-cholesterol responses of man to changes in fats in the diet J Lipid Res 26 1985 194 202
5. D.M. Dreon, K.M. Vranizan, R.M. Krauss, M.A. Austin, and P.D. Wood The effects of polyunsaturated fat vs. monounsaturated fat on plasma lipoproteins JAMA 263 1990 2462 2466
6. T.A. Kahlon, M. Saunders, F.I. Chow, M.M. Chir, and A.A. Betschart Influence of rice bran, oat bran and wheat bran on cholesterol and triglycerides in humans Cereal Chem 67 1990 439 443
7. M. Hegsted, M.M. Windhauser, F.B. Lester, and S.K. Morris Stabilized rice bran and oat bran lower cholesterol in humans FASEB J 4 1990 A368
8. R.D. Sharma, and C. Rukmini Rice bran oil and hypocholesterolemia in rats Lipids 21 1986 715 717
9. R.D. Sharma, and C. Rukmini Hypocholesterolemic activity of unsaponifiable matter of rice bran oil Indian J Med Res 85 1987 278 281
10. G.S. Seetharamaiah, and N. Chandrasekhra Studies on hypocholesterolemic activity of rice bran oil Atherosclerosis 78 1989 219 223
11. C. Raghuram, F. Brahmaji, and C. Rukmini Studies on hypolipidemic effects of dietary rice bran oil in human subjects Nutr Rep Int 39 1989 889 895
12. R.J. Nicolosi, L.M. Ausman, and D.M. Hegsted Rice bran oil lowers serum total and low density lipoprotein cholesterol and apo B levels in nonhuman primates Atherosclerosis 88 1991 133 142
13. A.H. Lichtenstein, L.M. Ausman, W. Carrasco, L.J. Gualtieri, J.L. Jenner, and J.M. Ordovas Rice bran oil consumption and plasma lipid levels in moderately hypercholesterolemic humans Arterioscler Thromb 14 1994 549 556
14. M. Sugano, and E. Tsuji Rice bran oil and cholesterol metabolism J Nutr 127 1997 521S 524S
15. R.J. Nicolosi, E.J. Rogers, L.M. Ausman, and F.T. Orthoefer Rice bran oil and its health benefits W. Marshall J. Wadsworth Rice Science and Technology 1992 Marcel Dekker Inc. New York 421 437
16. E.A.M. de Deckere, and O. Korver Minor constituents of rice bran oil as functional foods Nutr Rev 54 1996 S120 S126
17. J.B. Reeves III, and J.L. Weihrauch Composition of foods. Fats and oils. Agriculture handbook No. 8-4. 1979 United States Department of Agriculture Science and Education Administration, US Government Printing Office Washington (DC)
18. M.W. Formo, E.F. Jungermann, A. Norris, and N.O.V. Sonntag 4th ed. Bailey's Industrial Oil and Fat Products vol. 1 1979 Wiley New York (NY)
19. K. Nagao, M. Sato, M. Takenaka, M. Ando, M. Iwamoto, and K. Imaizumi Feeding unsaponifiable compounds from rice bran oil does not alter hepatic mRNA abundance for cholesterol metabolism-related proteins in hypercholesterolemic rats Biosci Biotechnol Biochem 65 2001 371 377
20. R.J. Nicolosi, L.M. Ausman, and D.M. Hegsted Lipoprotein levels in monkeys fed a diet containing rice oil Circulation 80 Suppl. 1989 II-86
21. E.J. Rogers Identification and quantitation of gamma oryzanol components and simultaneous assessment of tocols in rice bran oil J Am Oil Chem Soc 70 1993 301 307
22. M. Shinomiya, N. Morisaki, N. Matsuoka, S. Izumi, Y. Saito, and A. Kumagai Effects of γ-oryzanol on lipid metabolism in rats fed high-cholesterol diet Tohoku J Exp Med 141 1983 191 197
23. G.S. Seetharamaiah, and N. Chandrasekhara Hypocholesterolemic activity of oryzanol in rats Nutr Rep Int 38 1988 927 935
24. G.T. Yoshino, T. Kazumi, M. Amano, M. Takeiwa, T. Yamasaki, and S. Takashima Effects of gamma-oryzanol on hyperlipidemic subjects Curr Ther Res 45 1989 543 552
25. G.T. Yoshino, T. Kazumi, M. Amano, T. Makoto, T. Yamasaki, and D. Takashima Effects of gamma-oryzanol and probucol on hyperlipidemia Curr Ther Res 45 1989 975 982
26. J. Sasaki, Y. Takada, K. Handa, M. Kusuda, Y. Tanabe, and A. Matsunaga Effects of gamma-oryzanol on serum lipids and apolipoproteins in dyslipidemic schizophrenics receiving major tranquilizers Clin Ther 12 1990 263 268
27. E. Graf, and J.W. Eaton Suppression of colonic cancer by dietary phytic acid Nutr Cancer 19 1993 11 19
28. A.A. Qureshi, W.C. Burger, D.M. Peterson, and C.E. Elson The structure of an inhibitor of cholesterol biosynthesis isolated from barley J Biol Chem 261 1986 10544 10550
29. E.A. Serbinova, and L. Packer Antioxidant properties of alpha-tocopherol and alpha-tocotrienol Methods Enzymol 234 1994 354 366
30. D.K. Spady, and J.M. Dietschy Rates of cholesterol synthesis and low-density lipoprotein uptake in the adrenal glands of the rat, hamster and rabbit in vivo Biochim Biophys Acta 836 1985 167 175
31. N. Rong, L. Ausman, and R. Nicolosi Rice bran oil decreases plasma LDL cholesterol by inhibiting dietary cholesterol absorption FASEB J 8 1994 A162
32. A.H.M. Terpstra, J.C. Holmes, and R.J. Nicolosi The hypocholesterolemic effect of dietary soybean protein vs. casein hamsters fed cholesterol-free or cholesterol-enriched semipurified diet J Nutr 121 1991 944 947
33. B.R. Krause, R.F. Bousley, K.A. Kieft, and R.L. Stanfield Effect of the ACAT inhibitor CI-976 on plasma cholesterol concentrations and distribution in hamsters fed zero- and low-cholesterol diets Clin Biochem 25 1992 371 377
34. V.W. Rodwell, D.J. McNamara, and D.J. Shapiro Regulation of hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase Adv Enzymol Relat Areas Mol Biol 38 1973 373 412
35. N. Rong, L.M. Ausman, and R.J. Nicolosi Oryzanol decreases cholesterol absorption and aortic fatty streaks in hamsters Lipids 32 1997 303 309
36. D.B. Zilversmit A single blood sample dual isotope method for the measurement of cholesterol absorption in rats Proc Soc Exp Biol Med 140 1972 862 865
37. D.B. Zilversmit, and B. Hughes Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in fats J Lipid Res 15 1974 465 473
38. J. Balmer, and D.B. Zilversmit Effects of dietary roughage on cholesterol absorption cholesterol turnover and steroid excretion in the rat J Nutr 104 1974 1319 1328
39. P.J.H. Jones, L.M. Ausman, D.H. Croll, J.Y. Feng, E.A. Schaefer, and A.H. Lichtenstein Validation of deuterium incorporation against sterol balance for measurement of human cholesterol biosynthesis J Lipid Res 39 1998 1111 1117
40. L.M. Ausman, J.A. Johnson, C. Guidry, and P.P. Nair Fecal bile acids and neutral sterols in the cotton-top tamarin (Saguinus oedipus) Comp Biochem Physiol 105B 1993 655 663
41. K.D.R. Setchell, A.M. Lawson, N. Tanida, and J. Sjovall General methods for the analysis of metabolic profiles of bile acids and related compounds in feces J Lipid Res 24 1983 1085 1100
42. H.J. Harwood Jr., M. Schneider, and P.W. Stacpoole Measurement of human leukocyte microsomal HMG-CoA reductase activity J Lipid Res 25 1984 967 978
43. H.J. Harwood Jr., C.E. Chandler, L.D. Pellarin, F.W. Bangerter, R.W. Wilkins, and C.A. Long Pharmacologic consequences of cholesterol absorption inhibition: Alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin β-tigogenin cellobioside (CP-88818; tiqueside) J Lipid Res 34 1993 377 395
44. M.C. Kowala, and R.J. Nicolosi Effect of doxazosin on plasma lipids and atherogenesis: A preliminary report J Cardiovasc Pharmacol 13 Suppl. 2 1989 S45 S49
45. T.L. Foxall, G.T. Shwaery, A.F. Stucchi, R.J. Nicolosi, and S.S. Wong Dose-related effects of doxazosin on plasma lipids and aortic fatty streak formation in the hypercholesterolemic hamster model Am J Pathol 140 1992 1357 1363
46. M.C. Kowala, C.E. Mazzucco, K.S. Hartl, S.M. Seiler, G.A. Warr, and S. Abid Prostacyclin agonists reduce early atherosclerosis in hyperlipidemic hamsters. Octimibate and BMY 42393 suppress monocyte chemotaxis, macrophage cholesteryl ester accumulation, scavenger receptor activity, and tumor necrosis factor production Arterioscler Thromb 13 1993 435 444
47. SAS Institute, Inc. SAS-STAT guide for personal computer, Version 6 edition 1985 SAS Institute Incorporated Cary (NC)
48. D.W. Peterson Effect of soybean sterols in the diet on plasma and liver cholesterol in chicks Proc Soc Exp Biol Med 78 1951 143 147
49. O.J. Pollak Reduction of blood cholesterol in man Circulation 7 1953 702 706
50. J.M.R. Beveridge, W.F. Connell, G.A. Mayer, and H.L. Haust Plant sterols, degree of unsaturation, and hypocholesterolemic action of certain fats Can J Biochem 36 1958 895 911
51. H. Fisher, H.S. Weiss, and P. Griminger Influence of fatty acids and sterols on atherosclerosis in the avian abdominal aorta Proc Soc Exp Biol Med 106 1961 61 63
52. B.C. O'Brien, C.L. Skutches, G.R. Henderson, and R. Reiser Interrelated effects of food lipids on steroid metabolism in rats J Nutr 107 1977 1444 1454
53. M.T.R. Subbiah Dietary plant sterols: Current status in human and animal sterol metabolism Am J Clin Nutr 26 1973 219 225
54. B.J. Kudchodkar, L. Horlick, and H.S. Sodhi Effects of plant sterols on cholesterol metabolism in man Atherosclerosis 23 1976 29 248
55. G.C. Chiu Mode of action of cholesterol-lowering agents Arch Intern Med 108 1961 717 732
56. M.K. Kiribuchi, S. Miura, S. Tokuda, and T. Kaneda Hypocholesterolemic effect of triterpene alcohols with soysterol on plasma cholesterol in rats J Nutr Sci Vitaminol 29 1983 35 43
57. I. Ikeda, K. Nakashima-Yoshida, and M. Sugano Effects of cycloartenol on absorption and serum levels of cholesterol in rats J Nutr Sci Vitaminol 31 1985 375 384
58. L.B. Nguyen, S. Shefer, G. Salen, G.S. Tint, F. Ruiz, and J. Bullock Mechanisms for cholesterol homeostasis in rat jejunal mucosa: Effects of cholesterol, sitosterol, and lovastatin J Lipid Res 42 2001 195 200
59. C. Rukmini, and U.C. Raghuram Nutritional and biochemical aspects of the hypolipidemic action of rice bran oil: A review J Am Coll Nutr 10 1991 593 601
60. E.A. Trautwein, C. Schulz, D. Rieckhoff, A. Kunath-Rau, H.F. Erbersdobler, and W.A. de Groot Effect of esterified 4-desmethylsterols and -stanols or 4,4′-dimethylsterols on cholesterol and bile acid metabolism in hamsters Br J Nutr 87 2002 227 237
61. B. Cohen, N. Ayyad, T. Mikami, Y. Mikami, and E.H. Mosbach Effects of dietary fat and fatty acids on sterol balance in hamsters Lipids 29 1994 503 508
62. S.D. Turley, B.P. Daggy, and J.M. Dietschy Effect of feeding psyllium and cholestyramine in combination on low density lipoprotein metabolism and fecal bile acid excretion in hamsters with dietary-induced hypercholesterolemia J Cardiovasc Pharmacol 27 1996 71 79
63. M.L. Fernandez, L.R. Ruiz, A.K. Conde, D.-M. Sun, S.K. Erickson, and D.J. McNamara Psyllium reduces plasma LDL in guinea pigs by altering hepatic cholesterol homeostasis J Lipid Res 36 1995 1128 1138
64. R.A. Parker, T. Sabrah, M. Cap, and B.T. Gill Relation of vascular oxidative stress, α-tocopherol, and hypercholesterolemia to early atherosclerosis in hamsters Arterioscler Thromb Vasc Biol 15 1995 349 358
65. A.A. Qureshi, W.A. Salser, R. Parmar, and E.E. Emeson Novel tocotrienols of rice bran inhibit atherosclerotic lesions in C57BL/6 Apo-E deficient mice J Nutr 131 2001 2606 2618