Non-invasive measurement and imaging of tissue iron oxide nanoparticle concentrations in vivo using proton relaxometry

Journal of Physics: Conference Series

Volumn 17, Issue 1, 2005, Pages 122-126

  St Pierre, T G ^a   Clark, P R ^a   Chua Anusorn, W ^a   Fleming, A ^a   Pardoe, H ^a   Jeffrey, G P ^b   Olynyk, J K ^b   Pootrakul, P ^c   Jones, S ^d   Moroz, P ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c MAHIDOL UNIVERSITY   (Thailand)

^d Sirtex Medical Limited   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 23944469909     PISSN: 17426588     EISSN: 17426596     Source Type: Conference Proceeding    
DOI: 10.1088/1742-6596/17/1/018     Document Type: Conference Paper

References (12)

1. Safarik I and Safarikova M 2002 Magnetic nanoparticles and biosciences Monatshefte furChemie 133 737-59
2. Oppelt A and Grandke T 1993 Magnetic resonance imaging Superconductor Sci. Technology 6 381-95
3. Jensen J H and Chandra R 2002 Theory of nonexponential NMR signal decay in liver with iron overload or superparamagnetic iron oxide particles Magn. Reson. Med. 47 1131-8
4. Gossuin Y, Roch A, Muller R N, Gillis P and Lo Bue F 2002 Anomalous nuclear magnetic relaxation of aqueous solutions of ferritin: An unprecedented first-order mechanism Magn. Reson. Med. 48 959-64
5. St Pierre T G, Clark P R and Chua-anusorn W 2004 Single spin-echo proton transverse relaxometry of iron loaded liver NMR Biomedicine 17 446-58
6. St Pierre T G, Clark P R, Chua-anusorn W, Fleming A J, Jeffrey G P, Olynyk J K, Pootrakul P, Robins E and Lindeman R 2005 Noninvasive measurement and imaging of liver iron concentrations using proton magnetic resonance Blood 105 855-61
7. Clark P R, Chua-anusorn W and St Pierre T G 2003 Proton transverse relaxation rate (R2) images of iron-loaded liver tissue: Mapping local tissue iron concentrations with MRI Magn. Reson. Med. 49 572-5
8. Pardoe H, Clark P R, St Pierre T G, Moroz P and Jones S K 2003 A magnetic resonance imaging based method for measurement of tissue iron concentration in liver arterially embolized with ferrimagnetic particles designed for magnetic hyperthermia treatment of tumors Magn. Reson. Imaging 21 483-8
9. Moroz P, Pardoe H, Jones S K, St Pierre T G, Song S and Gray B N 2002 Arterial embolization hyperthermia: hepatic iron particle distribution and its potential determination by magnetic resonance imaging Phys. Med. Biol. 47 1591-602
10. Pardoe H, Chua-anusorn W, St Pierre T G and Dobson J 2003 Detection limits for ferrimagnetic particle concentrations using magnetic resonance imaging based proton transverse relaxation rate measurements Phys. Med. Biol. 48 N89-N96
11. Kirschvink J L, Kobayashi-Kirschvink A and Woodford B J 1992 Magnetite biomineralization in the human brain Proc. Nat. Acad. Sci. 89 7683-7
12. Dobson J 2002 Investigation of age-related variations in biogenic magnetite levels in the human hippocampus Exp. Brain Res. 144 122-6